Triglyceride News and Research

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Triglycerides are a type of fat in the bloodstream and fat tissue. Too much of this type of fat can contribute to the hardening and narrowing of your arteries. This puts you at risk of having a heart attack or stroke. Diseases such as diabetes, obesity, kidney failure or alcoholism can cause high triglycerides. Often, high triglycerides occur along with high levels of cholesterol, another type of fat. Triglycerides are measured along with cholesterol as part of a blood test. Normal triglyceride levels are below 150. Levels above 200 are high.

Short-term intensive weight management program effective alternative to bariatric surgery

A study by a team of clinicians and researchers at the Joslin Diabetes Center in Boston has shown for the first time that patients with diabetes who enrolled in a short-term intensive weight management program were able to lose weight and keep it off on their own for four years.

13 Jun 2012

People with fatty livers need to lose weight

Exercising moderately for 150 to 300 minutes a week does not improve lipoprotein metabolism in obese people with nonalcoholic fatty lipid disease, show findings from a US study.

31 May 2012

Obese patients with fatty liver disease show only small benefit on lipoprotein levels with moderate exercise

New research found that moderate exercise does not improve lipoprotein concentrations in obese patients with non alcoholic fatty liver disease (NAFLD). Results published in the June issue of Hepatology, a journal of the American Association for the Study of Liver Diseases, report that moderate physical activity produces only a small decrease in triglyceride and alanine transaminase (ALT) levels.

24 May 2012

BMP8B plays a key role in regulating thermogenesis in brown adipose tissue

Bone morphogenetic protein 8B (BMP8B) plays a key role in regulating thermogenesis in brown adipose tissue, according to the findings of a research work published in Cell, the journal with the most impact on the field of biomedicine and molecular biology.

23 May 2012

Solazyme first quarter total revenue increases to $13.6 million

Solazyme, Inc., a renewable oil and bioproducts company, announced today financial results for the first quarter ended March 31, 2012 and recent key corporate highlights.

8 May 2012

Isis commences ISIS-APOCIIIRx Phase 2 study in hypertriglyceridemia

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 2 study evaluating ISIS-APOCIIIRx in patients with hypertriglyceridemia.

5 May 2012

Study affirms necessity of heart rehabilitation programs for cardiac patients

University of Granada researchers affirm that it is "essential" that heart rehabilitation programs aimed at patients with any heart disease are established and provided to cardiac patients. The study included a sample of 200 patients suffering from heart disease.

4 May 2012

Symposium at EuroPRevent 2012 highlights benefits of oily fish consumption

Most people, whether healthy or having cardiovascular disease (CVD), would benefit from regular consumption of oily fish, concluded speakers at the EuroPRevent 2012 meeting. While eating whole fish undoubtedly offers the optimum approach for increasing omega-3 intakes in both primary and secondary prevention, delegates heard, supplements have a major role to play in increasing omega-3 intakes for people who do not like fish.

3 May 2012

Clinical trial to evaluate IGF-1 in children with SHANK3 deficiency

In an important test of one of the first drugs to target core symptoms of autism, researchers at Mount Sinai School of Medicine are undertaking a pilot clinical trial to evaluate insulin-like growth factor (IGF-1) in children who have SHANK3 deficiency (also known as 22q13 Deletion Syndrome or Phelan-McDermid Syndrome), a known cause of autism spectrum disorder (ASD).

25 Apr 2012

Study contains warning for obese expectant mother

A new University of Illinois study contains a warning for obese women who are planning pregnancies. Even if they eat a healthy diet when they are pregnant, their babies will develop in an unhealthy environment that places the infants at risk for future health problems.

16 Apr 2012

Researchers understand TG paradox in people of African descent

In most people, high blood levels of the fat known as triglycerides are an early warning sign of type 2 diabetes and metabolic syndrome, but in people of African descent these dangerous health conditions may go undiagnosed because triglyceride levels are not at the level used to diagnose metabolic syndrome (>150 mg/dL). This is known as the "TG (or lipid) paradox."

6 Apr 2012

Gene therapy improves chylomicron metabolism in LPLD patients

Amsterdam Molecular Therapeutics, a leader in the field of human gene therapy, announced today data demonstrating that one-time administration of the gene therapy Glybera (alipogene tiparvovec) is able to markedly improve chylomicron (fat particles in the blood) metabolism following consumption of a low fat meal.

29 Mar 2012

Study sheds light on the impact that zero-calorie beverages may have on health

Are diet sodas good or bad for you? The jury is still out, but a new study sheds light on the impact that zero-calorie beverages may have on health, especially in the context of a person's overall dietary habits.

29 Mar 2012

Obesity in later life linked to decreased mental faculties

The study found said out of 250 test subjects involving people over 59 years old, people between 60 and 70 who had the highest BMIs also had the lowest cognitive function. There was also a connection between visceral fat -- otherwise known as the belly fat around the torso - and poor mental abilities. The study, which was published in the British journal Age and Aging, measured the subjects fat-related measures including BMI, waist circumference and the amount of visceral - which could be close to organs - and subcutaneous -under the skin - fat using a abdominal CT scan. Cognitive ability was determined by a test called a Mini-Mental State Examination.

25 Mar 2012

Obese children with PNPLA3 and GCKR genetic variants more susceptible to fatty liver disease

New research found the genetic variant Patatin-like phospholipase domain containing protein-3 (PNPLA3) acting in conjunction with the glucokinase regulatory protein (GCKR) is associated with increased susceptibility to fatty liver disease in obese children.

23 Mar 2012

Metformin drug appears to prevent growth of atherosclerosis in patients with HIV

Treatment with the common diabetes drug metformin appears to prevent progression of coronary atherosclerosis in patients infected with HIV.

8 Mar 2012

New genetic resource to accelerate development of novel treatments for diseases

A new genetic resource from an international research consortium is expected to accelerate the development of new cures and treatments for a wide range of human diseases. This project, called the mouse "Collaborative Cross" (CC) resource, will increase the likelihood that experiments conducted in mice will advance our understanding of human biology.

17 Feb 2012

Pioglitazone can prevent long term effects of maternal obesity on offspring

In a study to be presented today at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting -, in Dallas, Texas, researchers will report findings that show that short therapy with the anti-diabetic medication Pioglitazone can prevent the long term effects of maternal obesity on offspring.

13 Feb 2012

Postmenopausal women at higher risk of stroke than they think

A new study by researchers at NYU Langone Medical Center and colleagues found that traditional risk factors for stroke - such as high cholesterol - are not as accurate at predicting risk in postmenopausal women as previously thought. Instead, researchers say doctors should refocus their attention on triglyceride levels to determine which women are at highest risk of suffering a devastating and potentially fatal cardiovascular event.

3 Feb 2012

Strong link between triglyceride levels and ischemic stroke in older women

In a surprising finding with significant implications for older women, researchers at Albert Einstein College of Medicine of Yeshiva University and NYU School of Medicine have found that high levels of triglycerides (blood fats) are the strongest risk factor for the most common type of stroke in older women – more of a risk factor than elevated levels of total cholesterol or of low-density lipoprotein (LDL) cholesterol.

3 Feb 2012