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Anti-IL-3 monoclonal antibodies to treat early stage Rheumatoid Arthritis in development

SuppreMol GmbH, an autoimmune disease specialist, today announced a licensing agreement with the University Hospital of Regensburg to develop SM401, a humanized anti-IL-3 monoclonal antibody for early diagnosis and treatment of Rheumatoid Arthritis (RA). SuppreMol will advance preclinical development of SM401 for treatment of RA. Simultaneously, the Company will further validate a highly sensitive human IL-3 diagnostic assay for patient stratification.

24 Jul 2012

Study represents new use of bone marrow transplantation

Researchers at Fred Hutchinson Cancer Research Center have opened a clinical trial to test the theory that giving a patient a new immune system can cure severe cases of Crohn's disease, a chronic inflammatory condition of the gastrointestinal tract.

24 Jul 2012

Aspirin use appears to reduce risk of Barrett's esophagus

Aspirin use appears to reduce the risk of Barrett's esophagus (BE), the largest known risk factor for esophageal cancer, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

24 Jul 2012

Ocular Therapeutix announces results from sustained release OTX-TP1 study on glaucoma

Ocular Therapeutix, Inc. announced today initial results of their sustained release travoprost-loaded punctum plug feasibility study for the treatment of glaucoma. This travoprost punctum plug (OTX-TP1) was evaluated for the reduction of elevated intraocular pressure in subjects with open-angle glaucoma or ocular hypertension over a 30 day period.

24 Jul 2012

NYU Langone's CMC offers tips to avoid injuries during summer

The summer is officially here and more people are playing sports and exercising outdoors. Experts from NYU Langone's Center for Musculoskeletal Care (CMC) offer tips to avoid injuries during these warmer months.

24 Jul 2012

Roundup: Plan for new Md. hospital advances; Outsourcing of prison health care gets scrutiny; Alaska Native medical center seen as model

Maryland officials are preparing to unveil this week a detailed plan for a $600 million regional hospital to replace the ailing Prince George's Hospital Center and establish a new health-care network throughout Prince George's County. The plans are part of a broad effort to improve health care in a county where an estimated 150,000 residents lack health insurance or have insufficient coverage and often rely on hospital emergency rooms for primary care.

24 Jul 2012

Once-daily Gralise significantly reduces pain intensity in PHN patients

Depomed, Inc. today announced that a report of Phase 3 data published online this month, ahead of the print edition, in the Clinical Journal of Pain showed that once-daily Gralise (gabapentin) tablets (1,800 mg) formulation significantly reduces intensity of pain in patients with postherpetic neuralgia (PHN).

23 Jul 2012

Positive results from BrainStorm's interim NurOwn stem cell therapy clinical trial for ALS

BrainStorm Cell Therapeutics announced today that it has completed the planned interim safety review of its Phase I/II ALS (Amyotrophic Lateral Sclerosis) clinical trial, indicating that autologous transplantation of the Company's cell therapy was well-tolerated, appears to be safe for use, and did not present any undue risks to the study participants.

23 Jul 2012

Why it's hard for medicine to fix its mistakes

ProPublica offers an examination of the challenges hospitals face in adopting procedures to address medical errors.

23 Jul 2012

New health professional roles emerge within the marketplace

This pair of stories from Kaiser Health News reports on new kinds of health professionals and the role they have within the health care continuum.

23 Jul 2012

Cerulean commences dosing in CRLX101 Phase 2 study for ovarian cancer

Cerulean Pharma Inc., a leader in developing dynamically tumor-targeted nanopharmaceuticals, today announced that the first patient has been dosed in a Phase 2 study of its lead candidate, CRLX101, in platinum-resistant ovarian cancer patients.

23 Jul 2012

CHD risk needs separating by glycemic status

People with diabetes not only have a higher incidence of coronary heart disease events compared with people without diabetes, but they differ in the type of risk factors they have for such events, report US researchers.

23 Jul 2012

Gout independent risk factor for myocardial infarction

Gout is a significant and independent risk factor for the development of myocardial infarction, even in younger patients and those with no other cardiovascular risk factors, researchers report in Rheumatology.

23 Jul 2012

AF deaths more likely on the weekend

In-hospital mortality rates for patients who have atrial fibrillation are significantly higher on the weekend than on weekdays, show US study results.

23 Jul 2012

Endovascular stroke therapy may prove beneficial in octogenarians

Use of intra-arterial therapy in octogenarian patients with stroke does not appear to increase their risk for dying in hospital above that seen with use of intravenous recombinant tissue plasminogen activator, a large study suggests.

23 Jul 2012

Pneumococcal revaccination needed in kidney transplant patients

Kidney transplant patients vaccinated against Streptococcus pneumoniae appear to be protected against pneumococcal infection for at least 15 months, research shows.

23 Jul 2012

Research finds new gene involved in epilepsy

New research conducted by neuroscientists from the Royal College of Surgeons in Ireland (RCSI) published in Nature Medicine has identified a new gene involved in epilepsy and could potentially provide a new treatment option for patients with epilepsy.

23 Jul 2012

First Edition: July 23, 2012

In this Kaiser Health News video, Greg Millett, a senior policy advisor in the Office of National AIDS Policy, tells Joanne Silberner that the president's National HIV/AIDS Strategy has improved coordination among federal agencies and that the 2010 health law will improve access to care for those living with HIV/AIDS.

23 Jul 2012

Noted philanthropist to launch mobile eye clinic in North India

Noted entrepreneur and philanthropist, Tej Kohli is all set to launch Drishti Rath, a complete eye clinic on wheels. After the successful launch of the corneal blindness eradication programme in 2010, which enabled hundreds of poverty stricken corneal blind to get vision and which is still running successfully across NCR and neighbouring rural areas, Tej is set to launch this first-of-its-kind initiative in North India.

23 Jul 2012

Study: Fewer Americans control their HIV infections

Tens of thousands of Americans taking potent antiretroviral therapies, or ART, to keep their HIV disease in check may not have as much control over the viral infection as previous estimates have suggested, according to results of a study by AIDS experts at Johns Hopkins and the University of Pennsylvania.

23 Jul 2012