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Scientists use unified analysis approach for diagnosing diseases with multiple genetic causes

Scientists at Baylor College of Medicine, Baylor Genetics, the University of Texas Health Science Center at Houston and Texas Children's Hospital are combining descriptions of patients' clinical features with their complex genetic information in a unified analysis to obtain more precise diagnoses of complex diseases, particularly those that involve more than one gene causing the condition.

8 Dec 2016

New approach uses silicon-based photonic probe to deliver light deep within brain tissues

The ability to stimulate neural circuits with very high precision light to control cells -- optogenetics -- is key to exciting advances in the study and mapping of the living brain.

8 Dec 2016

Ground-breaking study to explore effectiveness of using pre-hospital blood products

University of Warwick is collaborating with researchers at the NIHR Surgical Reconstruction and Microbiology Research Centre to support a ground-breaking new study to investigate the effectiveness of giving patients blood products immediately after a major injury or trauma - before they reach hospital.

8 Dec 2016

New stem cell research project to replicate brain's neural networks using 3D nanoprinting

Aston University has launched MESO-BRAIN, a major stem cell research project which it hopes will develop three-dimensional (3D) nanoprinting techniques that can be used to replicate the brain's neural networks.

8 Dec 2016

High adolescent BMI could impact cognitive function in midlife

Scientists at the Hebrew University of Jerusalem have found that higher Body Mass Index (BMI), if it begins in adolescence, can affect cognitive function in midlife. However, the effect appears to be restricted to adults who had lower socioeconomic position as children.

8 Dec 2016

Study explores men's perceptions of new HIV prevention treatment

The first study to explore United Kingdom men's perceptions of PrEP - a new HIV prevention treatment - has found that their opinions are negatively influenced by social stigma.

8 Dec 2016

Doctors need to replace sympathy and compassion with broader skill of empathy

Developing a broader skill of empathy is a more realistic goal for medical students and doctors than urging them to be more compassionate.

8 Dec 2016

New mathematical model suggests how AD may progress to become chronic

Successive flare-ups of the most common form of eczema may trigger an immune system overreaction, causing it to become a long-term condition in people.

8 Dec 2016

Many U.S. children do not receive evidence-based care for obesity despite USPSTF recommendations

Six years following the U.S. Preventive Services Task Force recommendation that clinicians screen and treat (or refer) children age six and older for obesity, most U.S. children still do not receive evidence-based care for obesity.

8 Dec 2016

Synthetic sgRNA for CRISPR genome editing

Chemically synthesized single guide RNA is the best way to do CRISPR genome editing. It is more pure than biological methods of creating guide RNAs, like in vitro transcription or plasmids. As a result, sgRNA leads to more consistency and higher quality.

8 Dec 2016

Stem cell-based risk scoring tool could predict AML patient’s response to standard treatment

Leukemia researchers at Princess Margaret Cancer Centre have developed a 17-gene signature derived from leukemia stem cells that can predict at diagnosis if patients with acute myeloid leukemia (AML) will respond to standard treatment.

8 Dec 2016

Researchers developing model to predict breast cancer patient’s response to chemotherapy

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators are working to predict, before treatment, whether an aggressive type of breast cancer will respond to chemotherapy.

8 Dec 2016

High levels of copeptin could increase risk of kidney, heart disease in Type 1 diabetes patients

Type 1 diabetes patients with elevated albumin in their urine had three times the risk of life-threatening kidney and cardiac disease as those with normal levels, according to researchers at the University of Colorado Anschutz Medical Campus.

8 Dec 2016

Researchers discover biological pathway that plays vital role in tumor development

An international team led by researchers from the Technion-Israel Institute of Technology's Rappaport Faculty of Medicine and the Technion Integrated Cancer Center has discovered a biological pathway that plays an important role in tumor development.

7 Dec 2016

Older women with metastatic breast cancer more likely to have genetic alterations in tumors

A University of North Carolina Lineberger Comprehensive Cancer Center-led analysis has found that women who are 65 years or older with metastatic breast cancer were more likely to have a cancer-linked genetic alterations in their tumors, and had a larger total number of genetic alterations, than younger patients overall.

7 Dec 2016

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of research findings today in the journal Science Translational Medicine.

7 Dec 2016

Preventing C. difficile infections could save thousands of lives and millions of health care dollars

The constant fear of having an embarrassing bathroom accident paralyzed Judy Post. Mental, physical and emotional stress consumed her. She wondered if her life would ever return to normal.

7 Dec 2016

Brain metastasis persists in women with HER2-positive breast cancer despite new targeted therapies

While new targeted treatments developed across the past two decades have led to dramatic survival improvements for women with HER2-positive metastatic breast cancer, University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators report that rates of breast cancer brain metastasis for women with this disease have not substantially declined.

7 Dec 2016

Brain activity of healthy older adults could help predict risk of falling

Falls are the leading cause of fatal and non-fatal injuries among older Americans and all too often lead to physical decline and loss of independence.

7 Dec 2016

Researchers developing opioid vaccines to help prevent overdose fatalities

In 2014, the number of deaths from opioid overdoses in the U.S. jumped to its highest level on record. The spike brought national attention to the epidemic and the awareness that new interventions are needed.

7 Dec 2016

Medicine News and Research

Scientists use unified analysis approach for diagnosing diseases with multiple genetic causes

New approach uses silicon-based photonic probe to deliver light deep within brain tissues

Ground-breaking study to explore effectiveness of using pre-hospital blood products

New stem cell research project to replicate brain's neural networks using 3D nanoprinting

High adolescent BMI could impact cognitive function in midlife

Study explores men's perceptions of new HIV prevention treatment

Doctors need to replace sympathy and compassion with broader skill of empathy

New mathematical model suggests how AD may progress to become chronic

Many U.S. children do not receive evidence-based care for obesity despite USPSTF recommendations

Synthetic sgRNA for CRISPR genome editing

Stem cell-based risk scoring tool could predict AML patient’s response to standard treatment

Researchers developing model to predict breast cancer patient’s response to chemotherapy

High levels of copeptin could increase risk of kidney, heart disease in Type 1 diabetes patients

Researchers discover biological pathway that plays vital role in tumor development

Older women with metastatic breast cancer more likely to have genetic alterations in tumors

Investigational diabetes drug that impedes Parkinson's progression getting ready for human trials

Preventing C. difficile infections could save thousands of lives and millions of health care dollars

Brain metastasis persists in women with HER2-positive breast cancer despite new targeted therapies

Brain activity of healthy older adults could help predict risk of falling

Researchers developing opioid vaccines to help prevent overdose fatalities

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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