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TMC receives NIH grant to evaluate pepducin in heart disease patients

Tufts Medical Center researchers are developing a first-of-its-kind drug to prevent deadly blood clots in heart disease patients, without the risk of serious bleeding associated with current medications. The National Heart, Lung, and Blood Institute of the National Institutes of Health has just awarded the team led by Athan Kuliopulos, MD, PhD, a $10 million grant to start testing a drug based on this novel technology.

4 Jul 2012

Study shows higher levels of phenolic compounds in organic tomatoes

Study conducted at the University of Barcelona shows that organic tomatoes contain higher levels of phenolic compounds than conventional tomatoes. Phenolic compounds are organic molecules found in many vegetables with proven human health benefits.

4 Jul 2012

Former President Bush in Zambia, Botswana to promote Pink Ribbon Red Ribbon initiative to fight cervical cancer

Former President George W. Bush and former first lady Laura Bush are traveling in Zambia and Botswana this week to promote "the Pink Ribbon Red Ribbon initiative spearheaded by his foundation that seeks to expand cervical and breast cancer screening and treatment in sub-Saharan Africa," CNN reports.

4 Jul 2012

Track-related injuries on the rise among U.S. children and adolescents

With the 2012 summer Olympic games about to take place in London, children everywhere are looking forward to watching their sports idols and role models take center stage. While the Olympics may inspire some to try a new sport, such as track, parents should be aware that this participation does not come without risk of injury.

4 Jul 2012

BCVI introduces comprehensive program for patients with BAV

Bicuspid aortic valve (BAV) disease is the most common congenital heart defect, occurring in approximately one to two percent of the population. The condition is present when the aortic valve, the valve that connects the heart to the main artery that distributes blood to the body, contains two leaflets instead of three, which open and close to regulate blood flow. As a result, the valve does not function properly, which can cause strain on the heart over time and may lead to serious health complications.

4 Jul 2012

Obesity epidemic requires new focus on controlling energy balance and preventing weight gain

As the United States confronts the growing epidemic of obesity among children and adults, a team of University of Colorado School of Medicine obesity researchers concludes that what the nation needs is a new battle plan - one that replaces the emphasis on widespread food restriction and weight loss with an emphasis on helping people achieve "energy balance" at a healthy body weight.

4 Jul 2012

High coffee consumption appears to reduce clinical pregnancy rate by 50%

Women who drink five or more cups of coffee a day severely reduce their chance of success from IVF treatment. Indeed, Danish investigators who followed up almost 4000 IVF and ICSI patients described the adverse impact as "comparable to the detrimental effect of smoking".

4 Jul 2012

Study to investigate costs and benefits of home-based HIV testing in Malawi

HIV remains a huge killer in Sub-Saharan Africa; especially in Malawi where up to 18% of the population is HIV positive. Early detection of the virus coupled with appropriate treatment can enormously improve both quality and length of life after diagnosis, which is why researchers at Warwick Medical School are embarking on a study to investigate the costs and benefits of home-based HIV testing in Malawi.

4 Jul 2012

CHS commences cash tender offer and consent solicitation for 8⅞% Senior Notes due 2015

Community Health Systems, Inc. today announced that its wholly-owned subsidiary, CHS/Community Health Systems, Inc., has commenced a cash tender offer for any and all of its approximately $934 million outstanding principal amount of 8⅞% Senior Notes due 2015.

4 Jul 2012

Nicotine addiction: An interview with Dr. Crystal

Cigarette smoking and nicotine addiction are widespread problems throughout the world. Many people continue to smoke despite high taxes and the available public information on the dangers of smoking.

3 Jul 2012

Prostate cancer patients with CVD are 52% more likely to regret their treatment choices

Prostate cancer patients with cardiovascular disease were 52 per cent more likely to regret their treatment choices than men without problems with their heart or veins, according to a study published in the July issue of the urology journal BJUI International.

3 Jul 2012

WSU researcher looks for clues on link between H1N1 flu and obesity

The recent H1N1 flu pandemic was found to be particularly dangerous to obese people, and a Wayne State University researcher is looking for clues as to why.

3 Jul 2012

Researchers use mouse model of autism to treat CTD

Using a mouse model of autism, researchers at the University of Cincinnati (UC) and Cincinnati Children's Hospital Medical Center have successfully treated an autism spectrum disorder characterized by severe cognitive impairment.

3 Jul 2012

NOTCH1 signaling promotes T-cell acute lymphoblastic leukemia-initiating cell regeneration

Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease.

3 Jul 2012

Researchers identify new gene target for leukemia therapy

Researchers at the University of Cincinnati (UC) Hoxworth Blood Center have discovered a new gene target for leukemia therapy.

3 Jul 2012

Study shows link between changing rates of antibiotic consumption and resistance

A new study published in Clinical Infectious Diseases and available online shows how seasonal changes in outpatient antibiotic use - retail sales of antibiotics typically get a boost during the winter - can significantly alter seasonal patterns of drug resistance. The findings suggest that hospital campaigns to reduce inappropriate antibiotic use should be coordinated with efforts in the broader community if they are to be most effective.

3 Jul 2012

GRP78 plays an important role in breast cancers that respond to anti-estrogen therapy

Researchers at Georgetown Lombardi Comprehensive Cancer Center have uncovered a single molecule they say is a major determinant of resistance to anti-estrogen therapy used to treat or prevent breast cancer in high-risk women.

3 Jul 2012

First Edition: July 3, 2012

Today's headlines include reports that continue to delve into the policy-oriented and political repercussions of last week's high court decision on the health law.

3 Jul 2012

Study identifies possible new approach to defeat bacterial infections

Research led by St. Jude Children's Research Hospital scientists has identified a possible new approach to defeating bacterial infections by targeting an innate immune system component in a bid to invigorate the immune response.

3 Jul 2012

Botulinum toxin may help prevent arm tremor in people with MS

Botulinum toxin may help prevent shaking or tremor in the arms and hands of people with multiple sclerosis (MS), according to new research published in the July 3, 2012, print issue of Neurology, the medical journal of the American Academy of Neurology.

3 Jul 2012