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Researchers investigate the role of a key component of the circadian clock in heart disease

Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition.

17 Jan 2022

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

A team of researchers assessed the immune response after administering a SARS-COV-2 vaccine in immuno-compromised subjects who are potentially at an increased risk to experience severe COVID-19 and inadequate response to SARS-CoV2 vaccination.

17 Jan 2022

Mental health of intensive care unit staff adversely impacted during COVID-19 pandemic

In a new study, a team of researchers surveyed the prevalence of mental health disorders in intensive care unit workers from England during the COVID-19 pandemic.

17 Jan 2022

Study finds evidence to strongly implicate OAS1 as an effector gene influencing COVID-19 severity

Researchers demonstrated that this splice variant is likely to be the single nucleotide polymorphism responsible for the association at this locus.

17 Jan 2022

Framework for understanding cross-country spread of COVID-19 in the context of the globally interconnected economy

A study published in Scientific Reports uses a three-dimensional conceptual model to examine COVID-19's global spatiotemporal dissemination.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

A new paper discusses the appearance of quasi-species in a single host with prolonged infection, with different rates of infectivity and sensitivity to neutralization by antibodies elicited by the Pfizer vaccine or those present in convalescent plasma.

17 Jan 2022

Study reveals aerosol transmission of SARS-CoV-2 via floor drains

A new study investigated COVID-19 cases in an apartment complex in South Korea and explored the possibility of aerosol transmission without direct contact between infected individuals with the help of molecular phylogenetic analysis and epidemiological surveillance.

17 Jan 2022

Study investigates whether immune responses to BNT162b2 vaccine differ in subjects with and without prior SARS-CoV-2 infection

A new paper published in the journal JCI Insight reports on the differential levels of immunity achieved in those with and without a history of prior infection with the virus following one and two doses of the earliest vaccines to be approved for emergency use.

17 Jan 2022

Study identifies cellular receptors for alphaviruses shared across mosquitoes, humans, and animals

A new study led by researchers at Harvard Medical School has identified a set of cellular receptors for at least three related alphaviruses shared across mosquitoes, humans, and animals that host the virus.

17 Jan 2022

New data fusion method classifies skin lesions more precisely than prior algorithms

Dermatologists typically classify skin lesions based on multiple data sources. Algorithms that fuse the information together can support this classification. An international research team has now developed an algorithm that classifies skin lesions more accurately than previous algorithms by using an improved data fusion process.

17 Jan 2022

Rapid antigen tests for SARS-CoV-2 have low overall rate of false-positive results

A timely new study investigated the incidence of false-positive results in a large sample of rapid antigen tests used to serially screen asymptomatic workers throughout Canada.

17 Jan 2022

Research provides a comprehensive map of exercise-induced signaling molecules present in the tissues

It is well established that exercise improves health, and recent research has shown that exercise benefits the body in different ways, depending on the time of day. But scientists still do not know why the timing of exercise produces these different effects.

17 Jan 2022

Pathogens turn off mitochondrial defense by hijacking a normal cellular response to stress

Mitochondria are known as energy suppliers for our cells, but they also play an important role in the defense against pathogens. They can initiate immune responses, and deprive pathogens of the nutrients they need to grow.

17 Jan 2022

New model to identify biological markers in patients with COVID-19 and other illnesses

Investigators who recently developed a mathematical model that indicated why treatment responses vary widely among individuals with COVID-19 have now used the model to identify biological markers related to these different responses.

17 Jan 2022

Study analyzes the impact of global trust in government due to the COVID-19 pandemic

In a week when the UK Prime Minister Boris Johnson has admitted to breaking Covid-19 lockdown rules, a new study has found that impartial, transparent and truthful government communications are fundamental for achieving and maintaining government trust during public health emergencies.

17 Jan 2022

Protein biomarkers in urine could be used to diagnose concussion and monitor recovery

Concussion can be frustratingly hard to diagnose and track. The injury doesn't show up on routine brain scans, and there is no definitive diagnostic test. It's usually diagnosed based on symptoms, and, in athletes, comparison with baseline testing if it was done. But concussion symptoms are non-specific, unreliable, and easily influenced by emotions.

17 Jan 2022

Discovery opens up the possibility of pursuing new therapies for FOP

Fibrodysplasia ossificans progressiva (FOP) is a rare disease characterized by extensive bone growth outside of the normal skeleton that pre-empts the body's normal responses to even minor injuries. It results in what some term a "second skeleton," which locks up joint movement and could make it hard to breathe.

16 Jan 2022

Pregnant women who contracted COVID-19 more likely to have poor birth outcomes

People who contracted COVID-19 while pregnant were more likely to have poor birth outcomes including preterm birth, small for gestational age, low birth weight, and stillbirth.

16 Jan 2022

New pioneering test helps predict the spread of deadly skin cancer

A pioneering test which reliably predicts the spread or return of the most deadly form of skin cancer has been developed by a team of Newcastle scientists and clinicians.

16 Jan 2022

Research News and Research

Researchers investigate the role of a key component of the circadian clock in heart disease

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

Mental health of intensive care unit staff adversely impacted during COVID-19 pandemic

Study finds evidence to strongly implicate OAS1 as an effector gene influencing COVID-19 severity

Framework for understanding cross-country spread of COVID-19 in the context of the globally interconnected economy

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

Study reveals aerosol transmission of SARS-CoV-2 via floor drains

Study investigates whether immune responses to BNT162b2 vaccine differ in subjects with and without prior SARS-CoV-2 infection

Study identifies cellular receptors for alphaviruses shared across mosquitoes, humans, and animals

New data fusion method classifies skin lesions more precisely than prior algorithms

Rapid antigen tests for SARS-CoV-2 have low overall rate of false-positive results

Research provides a comprehensive map of exercise-induced signaling molecules present in the tissues

Pathogens turn off mitochondrial defense by hijacking a normal cellular response to stress

New model to identify biological markers in patients with COVID-19 and other illnesses

Study analyzes the impact of global trust in government due to the COVID-19 pandemic

Protein biomarkers in urine could be used to diagnose concussion and monitor recovery

Discovery opens up the possibility of pursuing new therapies for FOP

Pregnant women who contracted COVID-19 more likely to have poor birth outcomes

New pioneering test helps predict the spread of deadly skin cancer

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