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Characteristics of initial hospitalization and readmissions among pediatric patients with COVID-19 in the US

Researchers from various institutions describe the characteristics, costs, and healthcare resource use associated with pediatric COVID-19 patients.

7 Jan 2022

Association of obstructive sleep apnea with hospitalization due to COVID-19

Researchers report that OSA is an independent risk factor for severe COVID-19.

7 Jan 2022

Study reveals the diverse ways that amphibians care for their young

Research led by Queen’s University Belfast has revealed the diverse ways that amphibians care for their young determine how many eggs they lay.

7 Jan 2022

New research may help better understand the causes of human diseases

New University of Gloucestershire research aims to increase our understanding of the causes of human diseases, potentially leading to the design of better treatments in the future.

7 Jan 2022

Exercise interventions could improve symptoms and quality of life for people with asthma

Interventions aimed at promoting physical activity in people with asthma could improve their symptoms and quality of life – according to new research from the University of East Anglia.

7 Jan 2022

Moderna announces initiation of Phase 1 study of its mRNA-1189 EBV vaccine candidate

Moderna, Inc., a biotechnology company pioneering messenger RNA therapeutics and vaccines, today announced the first participant has been dosed in the Phase 1 study of mRNA-1189, the Company's Epstein-Barr Virus vaccine candidate.

7 Jan 2022

RCSI study highlights the impact of pandemic on patients having emergency surgery

Patients undergoing emergency abdominal surgery spent less time in hospital during COVID-19, without any negative impact on outcomes, according to a new study from RCSI National Clinical Programme in Surgery and the Health Outcomes Research Centre at RCSI.

7 Jan 2022

FIND trial: Higher vitamin D intake does not affect mortality or cardiovascular disease, cancer risk

A trial by the University of Eastern Finland found that taking a much higher dose of vitamin D than recommended for five years did not affect total mortality or the incidence of cardiovascular disease or cancer in older men and women.

7 Jan 2022

Bacterial biofilms use a developmental patterning mechanism seen in plants and animals

Over the past several years, research from University of California San Diego biologist Gürol Süel's laboratory has uncovered a series of remarkable features exhibited by clusters of bacteria that live together in communities known as biofilms.

7 Jan 2022

Grouping tumors by 'immune archetypes' points the way to personalized immunotherapies

The UCSF researchers, led by first co-authors Alexis Combes, PhD, and Bushra Samad, MS, and senior author, Max Krummel, PhD, obtained tumor specimens from 78 UCSF clinicians, and surveyed 364 tumors biopsies from patients and categorized them into groups based on their immune microenvironment.

7 Jan 2022

Curia unveils comprehensive mRNA solution

Curia, formerly AMRI, a leading contract research, development and manufacturing organization, today unveiled its messenger RNA solution, which includes discovery, process development and mRNA drug substance production, through large-scale lipid manufacturing, lipid nanoparticle formulation and development for full-scale sterile fill-finish services.

From Curia Global, Inc. 7 Jan 2022

SARS-CoV-2 Omicron less pathogenic in hamsters

A new research paper posted as a preprint to the bioRxiv* server attempts to throw some light on this question by studying viral pathogenicity in golden hamsters, a valuable model for severe COVID-19 due to the development of reproducible weight loss and pneumonia after infection with the virus.

6 Jan 2022

Research uncovers how a mouse brain understands sensory information

The brain is the most complex organ in our body – constantly absorbing and interpreting our surroundings, and guiding our movement, thoughts, behaviors and emotions.

6 Jan 2022

In vivo generation of engineered CAR T cells can reduce fibrosis and restore cardiac function after heart injury

A novel immunotherapy strategy using in vivo generation of transient engineered chimeric antigen receptor (CAR) T cells, through the delivery of modified mRNA, can reduce fibrosis and restore cardiac function in a mouse model of heart failure, researchers report.

6 Jan 2022

Researchers explore consequences of eroding norms over release of self-spreading viruses

Decades of research by generations of virologists have generally established that the use laboratory-modified self-spreading viruses is too unpredictable to be applied safely outside of contained facilities.

6 Jan 2022

Ocean living microbes make oxygen in the dark

There is more going on in the deep, dark ocean waters than you may think: Uncountable numbers of invisible microorganisms go about their daily lives in the water columns, and now researchers have discovered that some of them produce oxygen in an unexpected way.

6 Jan 2022

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

An experimental immunotherapy can temporarily reprogram patients' immune cells to attack a specific target via only a single injection of messenger RNA (mRNA), similar to the mRNA-based COVID-19 vaccines, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

6 Jan 2022

Research News and Research

Characteristics of initial hospitalization and readmissions among pediatric patients with COVID-19 in the US

Association of obstructive sleep apnea with hospitalization due to COVID-19

Study reveals the diverse ways that amphibians care for their young

New research may help better understand the causes of human diseases

Exercise interventions could improve symptoms and quality of life for people with asthma

Moderna announces initiation of Phase 1 study of its mRNA-1189 EBV vaccine candidate

RCSI study highlights the impact of pandemic on patients having emergency surgery

FIND trial: Higher vitamin D intake does not affect mortality or cardiovascular disease, cancer risk

Bacterial biofilms use a developmental patterning mechanism seen in plants and animals

Grouping tumors by 'immune archetypes' points the way to personalized immunotherapies

Curia unveils comprehensive mRNA solution

SARS-CoV-2 Omicron less pathogenic in hamsters

Research uncovers how a mouse brain understands sensory information

In vivo generation of engineered CAR T cells can reduce fibrosis and restore cardiac function after heart injury

Researchers explore consequences of eroding norms over release of self-spreading viruses

Ocean living microbes make oxygen in the dark

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

Researchers study immune cell invasion process in living fruit fly embryos

More trusting societies achieve a faster decline in coronavirus infections and deaths

Study estimates the global prevalence of dementia in 2050

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