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Bacterial ‘fight club’ approach effective for finding new drugs from natural sources

Creating bacterial "fight clubs" is an effective way to find new drugs from natural sources. That is the conclusion of a team of Vanderbilt chemists who have been exploring ways to get bacteria to produce biologically active chemicals that they normally hold in reserve. These compounds are called secondary metabolites.

30 Jun 2015

Exhausted army of immune cells may damage the very body they are supposed to protect

An 'exhausted' army of immune cells may not be able to fight off infection, but if its soldiers fight too hard they risk damaging the very body they are meant to be protecting, suggests new research from the University of Cambridge.

30 Jun 2015

Tiny aquatic flatworms could replace existing animal models used in neurotoxicity tests

Laboratories that test chemicals for neurological toxicity could reduce their use of laboratory mice and rats by replacing these animal models with tiny aquatic flatworms known as freshwater planarians.

29 Jun 2015

Two physician-scientists in search for better Alzheimer's disease treatment

Two of the nation's leading physician-scientists in the search to better understand and treat Alzheimer's disease - William Mobley, MD, PhD, and Michael Rafii, MD, PhD - have been named interim co-directors of the Alzheimer's Disease Cooperative Study (ADCS), a major initiative formed in 1991 as a cooperative agreement between the National Institute on Aging (NIA) and the University of California, San Diego.

27 Jun 2015

SeraCare Life Sciences inks CRADA with NCI to create positive controls for cancer assays

SeraCare Life Sciences, a leading partner to global in vitro diagnostics manufacturers, today announced that it has signed a Cooperative Research and Development Agreement (CRADA) with the National Cancer Institute, part of the National Institutes of Health, to create reference materials and positive controls for cancer assays.

26 Jun 2015

IDT’s fully licensed MGB Eclipse qPCR probes available for online ordering

Integrated DNA Technologies (IDT), has become the only company to add fully licensed Minor Groove Binder (MGB) Eclipse GMP probes to its online service, enabling quick and efficient ordering.

From Integrated DNA Technologies 25 Jun 2015

Novogen’s chemotherapy drug Anisina proves as effective anti-cancer agent in animals

US-Australian drug discovery company, Novogen Limited announced today that its candidate cytotoxic chemotherapy drug, Anisina, has proved an effective anti-cancer agent in animals, the result of which it now has been fast-tracked by the Company to come into the clinic.

24 Jun 2015

Hiroshima University researchers study promising biomarker for severity of ARWMCs, endothelial function

A promising biomarker for the severity of age-related white matter changes (ARWMCs) and endothelial function was evaluated at Hiroshima University, Japan. The relationship between this biomarker, the telomeric 3'-overhang (G-tail) length, and cardiovascular risk in humans is unclear so far.

23 Jun 2015

Roche unveils series of new diagnostic technologies at EuroMedLab

Today at the 21st annual meeting of the IFCC-EFLM European Congress of Clinical Chemistry and Laboratory Medicines in Paris, France, Roche unveiled a series of new diagnostic technologies.

23 Jun 2015

Benitec, ReNeuron collaborate to launch new exploratory cellular therapy program

Benitec Biopharma is pleased to announce the launch of a new exploratory cellular therapy program including exosome-based delivery utilising the Company's proprietary ddRNAi technology. Entry into these areas have been facilitated by the commencement of a collaboration with UK-based stem cell therapeutics company, ReNeuron.

22 Jun 2015

Hitachi High-Technologies, QIAGEN form new strategic partnership to advance molecular testing

Hitachi High-Technologies Corporation and QIAGEN N.V. have entered into a long-term strategic collaboration involving initiatives to deliver important advances in molecular testing.

From QIAGEN Manchester Limited 18 Jun 2015

New DARPA grant supports Wyss Institute project that aims to fight gastrointestinal illness

For decades, American travelers to international destinations have been plagued by acute gastrointestinal illnesses that can arise from travel to other countries. The Center for Disease Control warns that depending on the destination, between 30 to 70 percent of travelers can expect to experience gastrointestinal distress from ingesting foreign or pathogenic bacteria that can be present in poorly sanitized water or food.

17 Jun 2015

Researchers create cell lines to study gene expression in precursor brown fat and white fat cells

Since the 2009 discovery that energy-burning brown fat can be active in adults, research has raced ahead to understand this tissue and exploit it to treat the epidemic of obesity. Active brown fat also may assist in directly easing the burden of diabetes and related metabolic diseases by lowering the levels of glucose and fatty acids in the bloodstream. But progress in studying human brown fat often has been slowed by difficulties in obtaining and studying samples of the human cells that develop into brown fat.

17 Jun 2015

Women who underwent uterine transplantation adjust to sudden restoration of fertility

In October last year the Gothenburg, Sweden, group of Mats Bra?nnstro?m announced the world's first live birth following the transplantation of a donated uterus.

17 Jun 2015

Study highlights medical, health care challenges faced by African American lesbian or bisexual women

More than one third of African American lesbian or bisexual women reported a negative experience with a heathcare provider and many of those women did not seek medical care the next time they were ill, according to a study published in LGBT Health, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

16 Jun 2015

Researchers develop hPSC-based system for producing connections between neurons in the brain

Human stem cells can be differentiated to produce other cell types, such as organ cells, skin cells, or brain cells. While organ cells, for example, can function in isolation, brain cells require synapses, or connectors, between cells and between regions of the brain. In a new study published in Restorative Neurology and Neuroscience, researchers report successfully growing multiple brain structures and forming connections between them in vitro, in a single culture vessel, for the first time.

16 Jun 2015

Supporting Innovation in Life Sciences

In this interview, News-Medical speaks to Ger Brophy about the importance of supporting technological innovation in the life sciences.

15 Jun 2015

Catalan researchers first to use liposomes to fight against diabetes

For the first time liposomes that imitate cells in the process of natural death have been used to treat Diabetes. Researchers at Germans Trias Research Institute (at UAB-Campus of International Excellence Sphere) generated liposomes in collaboration with professionals from the ICN2. PLOS ONE Journal publishes the work.

10 Jun 2015

Researchers investigate how ingested nanoparticles may influence metabolic processes

Researchers at Binghamton University believe understanding nano particles' ability to influence our metabolic processing may be integral to mediating metabolic disorders and obesity, both of which are on the rise and have been linked to processed foods.

10 Jun 2015

Ampio reports effects of Ampion in treating chronic pain caused by osteoarthritis of the knee

Ampio Pharmaceuticals, Inc. today announced three peer-review publications that report the multifaceted and synergistic effects of Ampion in the treatment of osteoarthritis in the knee.

9 Jun 2015

in vitro News and Research

Bacterial ‘fight club’ approach effective for finding new drugs from natural sources

Exhausted army of immune cells may damage the very body they are supposed to protect

Tiny aquatic flatworms could replace existing animal models used in neurotoxicity tests

Two physician-scientists in search for better Alzheimer's disease treatment

SeraCare Life Sciences inks CRADA with NCI to create positive controls for cancer assays

IDT’s fully licensed MGB Eclipse qPCR probes available for online ordering

Novogen’s chemotherapy drug Anisina proves as effective anti-cancer agent in animals

Hiroshima University researchers study promising biomarker for severity of ARWMCs, endothelial function

Roche unveils series of new diagnostic technologies at EuroMedLab

Benitec, ReNeuron collaborate to launch new exploratory cellular therapy program

Hitachi High-Technologies, QIAGEN form new strategic partnership to advance molecular testing

New DARPA grant supports Wyss Institute project that aims to fight gastrointestinal illness

Researchers create cell lines to study gene expression in precursor brown fat and white fat cells

Women who underwent uterine transplantation adjust to sudden restoration of fertility

Study highlights medical, health care challenges faced by African American lesbian or bisexual women

Researchers develop hPSC-based system for producing connections between neurons in the brain

Supporting Innovation in Life Sciences

Catalan researchers first to use liposomes to fight against diabetes

Researchers investigate how ingested nanoparticles may influence metabolic processes

Ampio reports effects of Ampion in treating chronic pain caused by osteoarthritis of the knee

Driving innovation in drug discovery with in vitro biology solutions eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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