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ASH report urges federal agencies to invest in 7 distinct areas of research

The American Society of Hematology (ASH), the world's largest professional society committed to the study and treatment of blood disorders, today issued a report urging federal agencies to coordinate hematology research funding around seven specific high-need areas that would produce the greatest impact and translate into improvements in patient care in the United States.

25 Apr 2012

Amgen announces agreement to acquire Mustafa Nevzat

Amgen, the world's largest biotechnology company, and Mustafa Nevzat Pharmaceuticals (MN) today announced an agreement under which Amgen will acquire 95.6 percent of shares in MN, a privately held Turkish pharmaceutical company, for an amount that values MN at US $700 million.

25 Apr 2012

Magnet hospitals can save lives of very low birth weight infants

Choosing the right hospital may make the difference between life and death for very low birth weight infants, according to research led by the University of Pennsylvania School of Nursing and released today in JAMA The Journal of the American Medical Association.

25 Apr 2012

NCH opens first suburban ambulatory surgery center

Nationwide Children's Hospital has opened its first suburban ambulatory surgery center. Located in Westerville, Ohio, the center is an extension of the current surgical services on the main campus, one that gives families an option for convenient access to a full spectrum of pediatric outpatient surgical services.

25 Apr 2012

CML and B-ALL arise from the long-term haematopoietic stem cells

Although people generally talk about "cancer", it is clear that the disease occurs in a bewildering variety of forms. Even single groups of cancers, such as those of the white blood cells, may show widely differing properties. How do the various cancers arise and what factors determine their progression? Clues to these two issues, at least for leukaemias, have now been provided by Boris Kovacic and colleagues at the University of Veterinary Medicine, Vienna.

25 Apr 2012

Severe fibrosis increases early atherosclerosis risk in patients with chronic HCV-1 infection

Italian researchers report that severe fibrosis increases the early atherosclerosis risk in patients with genotype 1 chronic hepatitis C virus (HCV) infection. A second study found that fatty liver disease also increases risk of developing atherosclerosis at an earlier period. Both studies appear in the May issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.

25 Apr 2012

Clinical trial to evaluate IGF-1 in children with SHANK3 deficiency

In an important test of one of the first drugs to target core symptoms of autism, researchers at Mount Sinai School of Medicine are undertaking a pilot clinical trial to evaluate insulin-like growth factor (IGF-1) in children who have SHANK3 deficiency (also known as 22q13 Deletion Syndrome or Phelan-McDermid Syndrome), a known cause of autism spectrum disorder (ASD).

25 Apr 2012

LCP molecules can treat prion diseases

Toxic prions in the brain can be detected with self-illuminating polymers. The originators, at Linköping University in Sweden, has now shown that the same molecules can also render the prions harmless, and potentially cure fatal nerve-destroying illnesses.

25 Apr 2012

Eating disorders can be triggered by lack of support following traumatic events

Eating disorders can be triggered by lack of support following traumatic events such as bereavement, relationship problems, abuse and sexual assault, according to research published in the May issue of the Journal of Clinical Nursing. Even changing school or moving home can prove too much for some young people and lead to conditions such as anorexia or bulimia.

25 Apr 2012

CU School of Medicine researcher devises new exercise for BPPV

A CU School of Medicine researcher who suffers from benign paroxysmal positional vertigo (BPPV) and had to "fix it" before she could go to work one day was using a maneuver to treat herself that only made her sicker. "So I sat down and thought about it and figured out an alternate way to do it. Then I fixed myself and went in to work" and discovered a new treatment for this type of vertigo.

24 Apr 2012

Neuron-killing pathology of AD requires presence of a-beta and elevated p-tau levels

According to a new study, the neuron-killing pathology of Alzheimer's disease (AD), which begins before clinical symptoms appear, requires the presence of both amyloid-beta (a-beta) plaque deposits and elevated levels of an altered protein called p-tau.

24 Apr 2012

Study finds better outcomes in VLBW infants born at RNE hospitals

In a study that included more than 72,000 very low-birth-weight infants, among those born in hospitals with recognition for nursing excellence (RNE), compared with non-RNE hospitals, there was a significantly lower rate of hospital infection, death at 7-days and severe intraventricular hemorrhage but not lower rates of death at 28-days or hospital stay mortality, according to a study in the April 25 issue of JAMA.

24 Apr 2012

State roundup: Mo. bill would outlaw federal health law; Texas docs got unwarranted Medicare bonuses

The Missouri House thinks the dreaded federal health care reform law is a crime. Or at least a misdemeanor. Going even further than other state legislatures fighting the law, the Missouri state House has passed a bill declaring the Affordable Care Act unconstitutional and therefore "altogether void and of no force." Any federal worker who tries to implement it would be committing a misdemeanor.

24 Apr 2012

Study finds increase in use of emergency CT in pediatric patients with abdominal pain

Computed tomography (CT) utilization in pediatric patients with non-traumatic abdominal pain increased in emergency departments each year between 1999 and 2007, according to a new study published online in the journal Radiology. The study authors found no corresponding increase in ultrasound use during the same period, despite research supporting it as an important diagnostic tool for assessing pediatric abdominal pain.

24 Apr 2012

Viewpoints: Myths about women voters; Stopping fake drugs; Medicaid innovation not easy; The war over women

Women vote based on "women's issues," such as abortion rights and contraception. A recent poll of voters in swing states showed that women's top priorities are health care, gas prices, unemployment and the deficit -- in that order -- with "government policies toward contraception" coming in last

24 Apr 2012

Women & Infants named lead center in 14-site study of cytomegalovirus

Women & Infants Hospital of Rhode Island, through its participation in the Maternal-Fetal Medicine Units Network, has been named the lead center in a 14-site, $25 million study of cytomegalovirus (CMV), the most common infection during pregnancy.

24 Apr 2012

Robot-assisted surgery more common and successful in treating prostate cancer

Robot-assisted surgery is now both more common and far more successful than radical "open" surgery to treat prostate cancer in the United States, according to a new Henry Ford Hospital study published in the current issue of the medical journal European Urology.

24 Apr 2012

Twins born to brain dead mother on a respirator for a month

Christine Bolden – a 26 year old woman was already brain dead from aneurysms, but doctors at a western Michigan hospital kept her on a respirator for a month to allow for the development of babies who were born prematurely at 25 weeks.

24 Apr 2012

Study: hUC-MSCs reduce inflammation that causes colitis

When laboratory mice were modeled with colitis and treated with human umbilical cord-derived mesenchymal cells, the cells homed in on the inflamed colon and effectively ameliorated colitis, reported a study published in a recent issue of Cell Transplantation.

24 Apr 2012

TopBP1 protein prevents early brain cells from DNA damage

St. Jude Children's Research Hospital scientists have rewritten the job description of the protein TopBP1 after demonstrating that it guards early brain cells from DNA damage. Such damage might foreshadow later problems, including cancer.

24 Apr 2012