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Antigenic map of SARS-CoV-2 variants reveals amino acid substitutions that govern immune escape and immunodominance

Researchers use antigenic cartography to analyze cross-reactivity patterns of eight groups of human sera on a panel of SARS-CoV-2 variants.

2 Feb 2022

Analysis of SARS-CoV-2 Omicron variant-associated travel restrictions worldwide

Researchers evaluate the travel restrictions placed by nations worldwide following the emergence of the SARS-CoV-2 Omicron variant.

2 Feb 2022

Omicron variant's 'milder' outcomes may be due to more population immunity

The SARS-CoV-2 Omicron variant's "milder" outcomes are likely due to more population immunity compared to earlier waves of the pandemic rather than the virus's properties, according to a paper by William Hanage, associate professor of epidemiology and co-director of the Center for Communicable Disease Dynamics at Harvard T.H. Chan School of Public Health, and Roby Bhattacharyya, assistant professor at Massachusetts General Hospital and Harvard Medical School and associate member at the Broad Institute of MIT and Harvard.

2 Feb 2022

Booster dose of Covaxin vaccine candidate neutralizes Omicron and Delta variants

Researchers evaluate the neutralization potential of sera samples from subjects boosted with the Covaxin against the SARS-CoV-2 Omicron variant.

2 Feb 2022

New evidence that positive framing could improve COVID vaccine uptake globally

Researchers applied message framing techniques to the side effects associated with the AstraZeneca, Pfizer, and Moderna COVID-19 vaccines.

2 Feb 2022

UK's world-leading human challenge study provides new insights into mild SARS-CoV-2 infections

Findings from the UK's world-leading human challenge study provide new insights into mild infections with SARS-CoV-2 in healthy young adults.

2 Feb 2022

NIAID's new pandemic preparedness efforts aim to characterize prototype and priority pathogens

As the global COVID-19 pandemic continues into its third year, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, is focusing on preparing for a range of other viral threats that could cause a public health emergency.

2 Feb 2022

Combined treatment strategy essential to minimize lung sequelae in COVID-19 patients

A combined treatment strategy targeting SARS-CoV-2 symptoms and severe lung tissue injury is essential to minimize lung sequelae- chronic complications resulting from COVID-19 infection, according to a review published this week in Clinical Microbiology Reviews, a journal of the American Society for Microbiology.

2 Feb 2022

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

Exposure to SARS-CoV-2 by infection or vaccination generates immune cells that provide long-term immunity. These long-lived memory T cells play a key role in preventing severe cases of Covid-19. Researchers at the University of Zurich have now discovered how these memory T cells form.

2 Feb 2022

Researchers discover mechanism behind loss of smell in people with COVID-19

Researchers have discovered a mechanism that may explain why people with COVID-19 lose their sense of smell.

2 Feb 2022

Exploring protection via a 4th dose of BNT162b2 against SARS-CoV-2 Omicron variant in Israel

In a new study, researchers from Israel assessed the effectiveness of a fourth dose of BNT162b2 vaccine (Pfizer-BioNTech) against confirmed infection and severe illness due to COVID-19.

2 Feb 2022

SARS-CoV-2 omicron variant shown to replicate less efficiently in human lungs

A new study revealed that the omicron variant replicates more effectively in the human bronchus than other SARS-CoV-2 variants, yet this new variant has lower replication competence in the lungs.

2 Feb 2022

Researchers explore SARS-CoV-2 seroprevalence in a school community in Switzerland

In a new study, researchers evaluated SARS-CoV-2 seroprevalence in children, parents, and school personnel of cantonal districts of Zurich, Switzerland, between June 2020 and April 2021.

2 Feb 2022

Rapid antigen test for SARS-CoV-2 shows lower sensitivity

In a new study, researchers assessed a rapid antigen (Ag) test for SARS-CoV-2.

2 Feb 2022

Safety and immunogenicity of high-dose quadrivalent influenza vaccine and mRNA-1273 vaccine booster in older adults

A new study has determined the safety and immunogenicity after concomitant administration of QIV-HD and a third dose of the mRNA-1273 vaccine among older adults in the USA

2 Feb 2022

N gene target failure method effectively detects SARS-CoV-2 Omicron in clinical samples

In a new study, researchers demonstrated that a commercial real-time polymerase chain reaction (RT-PCR) assay rapidly detects the SARS-CoV-2 Omicron variant.

2 Feb 2022

The ability of individuals to cross-recognize the Omicron spike protein following vaccination or prior infection

Scientists studied the ability of T cells to react with the Omicron spike.

2 Feb 2022

Quantitative framework to investigate the dynamic mechanism of host immune response confronting SARS-CoV-2 infection

The authors highlight that they have created a quantitative framework that allows the dynamic mechanism of the immune response to SARS-CoV-2 to be properly investigated.

2 Feb 2022

Determining the limit of detection for SARS-CoV-2 Omicron variant using rapid antigen tests

In a new study, researchers examined the analytical sensitivity of three widely used rapid antigen tests used in the USA to detect the SARS-CoV-2 Omicron variant, compared with the WA1 strain.

2 Feb 2022

Impact of equitable access to COVID-19 vaccines for all countries

In a new study, a team of researchers proposed a metapopulation model to assess the different SARS-CoV-2 vaccine allocation strategies adopted globally.

2 Feb 2022

SARS News and Research

Antigenic map of SARS-CoV-2 variants reveals amino acid substitutions that govern immune escape and immunodominance

Analysis of SARS-CoV-2 Omicron variant-associated travel restrictions worldwide

Omicron variant's 'milder' outcomes may be due to more population immunity

Booster dose of Covaxin vaccine candidate neutralizes Omicron and Delta variants

New evidence that positive framing could improve COVID vaccine uptake globally

UK's world-leading human challenge study provides new insights into mild SARS-CoV-2 infections

NIAID's new pandemic preparedness efforts aim to characterize prototype and priority pathogens

Combined treatment strategy essential to minimize lung sequelae in COVID-19 patients

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

Researchers discover mechanism behind loss of smell in people with COVID-19

Exploring protection via a 4th dose of BNT162b2 against SARS-CoV-2 Omicron variant in Israel

SARS-CoV-2 omicron variant shown to replicate less efficiently in human lungs

Researchers explore SARS-CoV-2 seroprevalence in a school community in Switzerland

Rapid antigen test for SARS-CoV-2 shows lower sensitivity

Safety and immunogenicity of high-dose quadrivalent influenza vaccine and mRNA-1273 vaccine booster in older adults

N gene target failure method effectively detects SARS-CoV-2 Omicron in clinical samples

The ability of individuals to cross-recognize the Omicron spike protein following vaccination or prior infection

Quantitative framework to investigate the dynamic mechanism of host immune response confronting SARS-CoV-2 infection

Determining the limit of detection for SARS-CoV-2 Omicron variant using rapid antigen tests

Impact of equitable access to COVID-19 vaccines for all countries

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