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John Oldham redefines the landscape of personality disorders

In a comprehensive Genomic Press Interview published today in Brain Medicine, John M. Oldham, MD, MS, one of psychiatry's most influential architects of personality disorder theory, traces his remarkable journey from frontier medicine roots in Oklahoma to revolutionizing how mental health professionals understand and diagnose personality pathology.

11 Jun 2025

Patient-derived xenograft models may become an indispensable tool in precision oncology

Cancer remains one of the most pressing global health challenges, with millions of new diagnoses each year. While precision medicine and targeted therapies have transformed treatment strategies, many patients still face drug resistance and disease recurrence.

10 Jun 2025

Energy drain from antibiotics spurs bacteria to resist treatment faster

Antibiotics are supposed to wipe out bacteria, yet the drugs can sometimes hand microbes an unexpected advantage.

9 Jun 2025

New technique creates multimeric aptamers for precision virus targeting

We have all heard of antibodies – proteins produced by our bodies to bind to viruses or bacteria, marking them for elimination by the immune system.

6 Jun 2025

Maternal exposure to metals rewires infants’ gut and resistance genes

Prenatal exposure to trace elements like selenium, copper, and arsenic can significantly alter the infant gut microbiome, metabolism, and antibiotic resistance gene patterns. These changes appear as early as three months and evolve during the first year of life.

5 Jun 2025

Artificial intelligence and neuroscience reveal hidden functions of brain's reward center

By crossing AI and neuroscience, a team from UNIGE, Harvard and McGill has revealed the computational potential of a brain area at the heart of motivation.

5 Jun 2025

Early gut bacteria may help protect babies from respiratory infections

A baby's makeup of gut bacteria - their microbiome - which starts to form as soon as they are born, could help protect against viral infections later in childhood, a new study suggests.

5 Jun 2025

Mass treatment with the antibiotic azithromycin may lead to increased drug resistance

Efforts to reduce child mortality in Africa via mass treatment with the antibiotic azithromycin (AZM) may lead to increased drug resistance in bacteria that frequently cause pneumonia and meningitis, highlighting the need for careful monitoring, finds a new study led by UCL.

4 Jun 2025

Experts review how 12-hour biological cycles operate in mice, with clues in humans

Researchers uncover how 12-hour biological rhythms operate in mammals, exploring their unique mechanisms and potential evolutionary ties to ancient tidal cycles. These rhythms could play a critical role in metabolism, stress response, and disease risk.

4 Jun 2025

Study traces longstanding presence of African swine fever in Europe

A new study in Genome Biology and Evolution, published by Oxford University Press, finds that the African Swine Fever virus, currently circulating in Europe, is not the result of a recent introduction.

4 Jun 2025

Individual immune variation shapes the evolution of influenza strains

A new study has shown that person-to-person variation in antibody immunity plays a key role in shaping which influenza (flu) strains dominate in a population.

3 Jun 2025

Carotid plaques may quietly become more dangerous over time

Using data from the Rotterdam Study in the Netherlands, researchers have uncovered that carotid artery plaques can undergo potentially dangerous changes over time in patients without symptoms, according to a study was published today in Radiology, a journal of the Radiological Society of North America.

3 Jun 2025

Fujifilm rebrands Life Sciences Companies to strengthen position as strategic partners for life, offering end-to-end solutions

FUJIFILM Corporation's Life Sciences Group companies, a portfolio of businesses offering products, services and comprehensive solutions that span all stages of therapeutic development from discovery through to commercialization, today announced new names and identities as part of a strategic positioning effort.

3 Jun 2025

Genome doubling identified as common event in metastatic cancer evolution

When cancer spreads from a primary tumor to new sites throughout the body, it undergoes changes that increase its genetic complexity.

2 Jun 2025

Experts chart path to bring microbiome science into routine clinical care

Despite rapid advances in sequencing and bioinformatics, translating microbiome science into clinical practice presents significant challenges, including the lack of standardized protocols, limited clinical evidence, and logistical barriers. This Cell perspective outlines key actions, standardization, robust trial design, and clinician education to move microbiome diagnostics and therapeutics from bench to bedside.

2 Jun 2025

Microfluidic contact lenses emerge as next generation tools for eye care

The tear film coating the eye offers a window into a person's systemic and ocular health, carrying biomarkers such as glucose, electrolytes, and proteins.

31 May 2025

New trial offers hope for men with aggressive prostate cancer

Many men with aggressive prostate cancer can experience a high rate of recurrence despite treatment.

30 May 2025

Genetic evolution of plague bacterium may have prolonged historic pandemics

Scientists at the Institut Pasteur and McMaster University have discovered that the evolution of a gene in the bacterium that causes bubonic plague, Yersinia pestis, may have prolonged the duration of two major pandemics.

29 May 2025

Non-permanent wireless forehead e-tattoo measures mental strain

Researchers gave participants face tattoos that can track when their brain is working too hard. Published May 29 in the Cell Press journal Device, the study introduces a non-permanent wireless forehead e-tattoo that decodes brainwaves to measure mental strain without bulky headgear.

29 May 2025

Wilms tumor found to contain millions of genetic changes

Researchers have uncovered that some childhood cancers have a substantially higher number of DNA changes than previously thought, changing the way we view children's tumours and possibly opening up new or repurposed treatment options.

29 May 2025