SARS CoV 2 News and Research

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Mix-and-match of COVID-19 vaccine boosters found to be safe and effective

In adults who had previously received a full regimen of a COVID-19 vaccine approved or authorized by the Food and Drug Administration (FDA), an additional dose of any of these COVID-19 vaccines was safe and prompted an immune response, according to study findings published Jan. 26 in The New England Journal of Medicine.

28 Jan 2022

Studying the effect of COVID-19 mRNA vaccine on human lung carcinoma epithelial cells using Raman spectroscopy and imaging

Researchers from the Lodz University of Technology have been investigating the effects of the mRNA COVID-19 vaccines on human lung carcinoma cells.

28 Jan 2022

Novel “prime and spike” vaccine strategy leverages existing immunity generated by primary COVID-19 vaccination

Scientists from Yale University, USA, have recently developed an intranasal spike boosting vaccine that induces robust mucosal immunity in the respiratory tract,

28 Jan 2022

Immuno-proteomic profiling suggests aberrant immune cell regulation associated with post-COVD-19 infection

A new study investigates the association between the immune system and respiratory complications post-COVID-19 infection.

28 Jan 2022

Study explores vaccine effectiveness against the SARS-CoV-2 Omicron variant in patients receiving hemodialysis

A new study studied the clinical impact of SARS-CoV-2 Omicron infection, and vaccine effectiveness, in patients undergoing in-center hemodialysis (IC-HD).

28 Jan 2022

A synthesis of evidence sheds light on major immune components and mechanisms involved in COVID-19

New research highlights principal host factors that may explain the immune responses to SARS-CoV-2 and its variants in the context of infection susceptibility, disease severity, and previous immunity.

28 Jan 2022

Evidence on intra-host recombination of SARS-CoV-2 during superinfection by Alpha and Epsilon variants in USA

A new study captured an instance of SARS-CoV-2 superinfection in an individual, simultaneously infected by two SARS-CoV-2 variants, Alpha and Epsilon during the second COVID-19 wave in New York City in early 2021.

28 Jan 2022

Reduced neutralization against Omicron variant in fully immunized adolescents with BNT162b2 vaccine

Researchers compare the humoral immune response in adolescents and adults after being completely immunized with the Pfizer BNT162b2 vaccine.

28 Jan 2022

γ’ fibrinogen as a disease progression marker for COVID-19

Levels of the inflammatory biomarker gamma prime fibrinogen (γ' Fbg) varies according to severity in COVID-19 patients.

28 Jan 2022

Impact of the Omicron variant on disease severity and healthcare utilization

Researchers compare trends in disease and hospital utilization during Omicron circulation to the previous SARS-CoV-2 variants in the U.S.

28 Jan 2022

Impact of DNA clearance on mortality in patients with severe COVID-19 infections

In a new study, researchers conducted activity-based proteomic profiling of patients who had severe SARS-CoV-2 infections to understand the impact of DNA clearance on mortality.

28 Jan 2022

Potential therapy candidates for patients infected with the SARS-CoV-2 Omicron variant

Researcher discusses several promising therapeutic candidates that have been proposed for the treatment of patients infected with the Omicron variant.

28 Jan 2022

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

This study showed inhalable Covid-19 mimetic particle carriers as potential, versatile, aerosolizable COVID-19 vaccine candidates if worked on with continued optimization and refinement.

28 Jan 2022

Magnetic nanoparticles for SARS-CoV-2 and other virus detection systems

Researchers discuss the contributions that have been provided by magnetic nanoparticles for the molecular diagnosis of human viruses.

28 Jan 2022

Exploring receptor-blocking conserved non-neutralizing antibodies for SARS-CoV-2 therapy

In a new study, researchers hypothesized and developed broad-spectrum SARS-CoV-2 inhibitors, ReconnAbs, by modifying the existing non-neutralizing antibodies targeted towards the highly conserved epitopes of the SARS-CoV-2 spike (S) protein combined with a receptor-blocking component.

28 Jan 2022

E406W mutation on SARS-CoV-2 RBD escapes monoclonal antibody cocktail-mediated neutralization

Researchers look to better understand the molecular basis of E406W-mediated escape from the REGEN-COV cocktail and cilgavimab.

28 Jan 2022

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

Researchers investigate the possible efficacy of IFN-λ in the context of SARS-CoV-2 infection in mice.

28 Jan 2022

Airborne SARS-CoV-2 transmission beyond home isolation rooms may pose infection risk to others

A Rutgers study has detected tiny airborne particles containing RNA from the SARS-CoV-2 that causes COVID-19, both inside and outside of the rooms in which infected people were self-isolating at home. This finding suggests that airborne transmission beyond the isolation rooms in homes may pose a risk of infection to other home occupants.

28 Jan 2022

New simulation model shows how likely the SARS-CoV-2 virus spreads in different school settings

A year ago, the whole world discussed: is it irresponsible to send children to school during a pandemic, or do measures exist that can prevent corona clusters so efficiently that schools can stay open (or reopen)?

28 Jan 2022

New trial tests the effectiveness of hyperimmune immunoglobulin for hospitalized COVID-19 patients

This scanning electron microscope image shows SARS-CoV-2 (round gold particles) emerging from the surface of a cell cultured in the lab. SARS-CoV-2, also known as 2019-nCoV, is the virus that causes COVID-19.NIAID

28 Jan 2022

SARS CoV 2 News and Research

Mix-and-match of COVID-19 vaccine boosters found to be safe and effective

Studying the effect of COVID-19 mRNA vaccine on human lung carcinoma epithelial cells using Raman spectroscopy and imaging

Novel “prime and spike” vaccine strategy leverages existing immunity generated by primary COVID-19 vaccination

Immuno-proteomic profiling suggests aberrant immune cell regulation associated with post-COVD-19 infection

Study explores vaccine effectiveness against the SARS-CoV-2 Omicron variant in patients receiving hemodialysis

A synthesis of evidence sheds light on major immune components and mechanisms involved in COVID-19

Evidence on intra-host recombination of SARS-CoV-2 during superinfection by Alpha and Epsilon variants in USA

Reduced neutralization against Omicron variant in fully immunized adolescents with BNT162b2 vaccine

γ’ fibrinogen as a disease progression marker for COVID-19

Impact of the Omicron variant on disease severity and healthcare utilization

Impact of DNA clearance on mortality in patients with severe COVID-19 infections

Potential therapy candidates for patients infected with the SARS-CoV-2 Omicron variant

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

Magnetic nanoparticles for SARS-CoV-2 and other virus detection systems

Exploring receptor-blocking conserved non-neutralizing antibodies for SARS-CoV-2 therapy

E406W mutation on SARS-CoV-2 RBD escapes monoclonal antibody cocktail-mediated neutralization

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

Airborne SARS-CoV-2 transmission beyond home isolation rooms may pose infection risk to others

New simulation model shows how likely the SARS-CoV-2 virus spreads in different school settings

New trial tests the effectiveness of hyperimmune immunoglobulin for hospitalized COVID-19 patients

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