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Researchers to use three-dimensional liver mimic for toxicity study on human body

The liver is the primary organ in the human body that metabolizes foreign compounds such as drugs, alcohol, cigarette smoke, and environmental chemicals. Using the liver as an alarm system, researchers are starting to better understand the different levels of toxicity from these compounds and their effects on the human body.

7 Jun 2011

ImaginAb, Oxford BioMedicaplc enter research deal to develop in vivo diagnostic imaging agent

Oxford BioMedicaplc, a leading gene therapy company, today announces that it has signed a research collaboration agreement with ImaginAb, Inc., a biotechnology company specialising in the development of engineered antibody fragments for diagnostic imaging and novel therapeutic applications, to engineer an in vivo diagnostic imaging agent using an antibody targeting the Company's proprietary 5T4 tumour antigen.

7 Jun 2011

ITI receives FDA clearance for new Q fever assay kit

This week the U.S. Food and Drug Administration cleared the first nucleic acid amplification In vitro diagnostic (IVD) test that detects Coxiella burnetii, the bacteria that causes Q fever.

7 Jun 2011

Genesis Biopharma expands clinical focus to develop Contego for Stage IV metastatic melanoma

Genesis Biopharma, Inc., a biotechnology company developing targeted cancer therapies, today announced an expanded clinical focus to include an autologous cell therapy product candidate, Contego™, for the treatment of Stage IV metastatic melanoma.

6 Jun 2011

Azellon receives MHRA approval to initiate stem cell bandage clinical trial in torn meniscal cartilage

Millions of people with knee injuries could benefit from a new type of stem cell bandage treatment if clinical trials are successful. The world's first clinical trial for the treatment of patients with torn meniscal cartilage has received approval from the UK regulatory agency, the MHRA1, to commence.

6 Jun 2011

Researcher finds thyroid cancer gene inhibits spread of malignant cells

A mutant gene long thought to accelerate tumor growth in thyroid cancer patients actually inhibits the spread of malignant cells, showing promise for novel cancer therapies, a Mayo Clinic study has found.

6 Jun 2011

Anti-Mullerian hormone test can indicate reproductive function in young women with cancer

A test that shows how many eggs a woman has in her ovaries may help young women with breast cancer know what their reproductive function will be after chemotherapy, a new study finds. The results will be presented Sunday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

Additional data supporting utility of PAM50 gene signature for breast cancer to be presented at ASCO 2011

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and developer of molecular diagnostics, today announced that researchers will present additional evidence for the potential utility of profiling breast cancer based on the PAM50 gene signature at the 2011 American Society of Clinical Oncology annual meeting taking place in Chicago, Illinois from June 3-7.

4 Jun 2011

Scientists discover new compound that inhibits bitterness

Although bitterness can sometimes be desirable - such as in the taste of coffee or chocolate - more often bitter taste causes rejection that can interfere with food selection, nutrition and therapeutic compliance. This is especially true for children. Now, scientists from the Monell Center and Integral Molecular describe the discovery of a compound that inhibits bitterness by acting directly on a subset of bitter taste receptors.

3 Jun 2011

Clovis Oncology, Roche partner to develop in vitro PCR-based diagnostic test for NSCLC

Clovis Oncology, Inc. and Roche, announced today that they have entered into an agreement to develop an in vitro PCR based companion diagnostic test.

2 Jun 2011

Investigators to examine how Ephb2 gene causes ependymoma in children

Armed with new grant support, investigators at Nationwide Children's Hospital plan to examine how a common gene of the nervous system leads to the development of a devastating brain tumor, ependymoma.

2 Jun 2011

Niiki Pharma to present NKP-1339 Phase I trial against metastatic cancer at ASCO 2011

Niiki Pharma announced today that it will present interim data from the ongoing Phase I clinical study for its lead product, NKP-1339, at the 2011 American Society for Clinical Oncology meeting in Chicago, IL.

2 Jun 2011

Pacific Reproductive Center celebrates Annual Baby Reunion in Torrance

When April Gooding was born 19 years ago in Torrance, infants like her were called "test tube babies" and in vitro fertilization was still considered experimental. Nearly two decades later, almost 4 million IVF babies have been born, including several hundred who will join April and the fertility expert who helped create her as one of his first successes.

1 Jun 2011

New ways to replicate what happens to stents tucked inside blood vessels

If by chance you should have a stent inserted in a clogged coronary artery, you can probably count on it staying around for a very long time. So it's important to know what will happen to it.

27 May 2011

Phadia ImmunoCAP Specific IgE blood test used in largest cross-sectional allergy study

Phadia, the worldwide leader of in vitro allergy diagnostics, is pleased to contribute to the largest cross-sectional allergy study ever conducted through the use of its ImmunoCAP Specific IgE blood test, the market leading in vitro allergy diagnostic test.

27 May 2011

Quest Diagnostics announces results of largest ImmunoCAP cross-sectional allergy study

ImmunoCAP, the worldwide leader of in vitro allergy diagnostics, is pleased to present the results of the largest cross-sectional allergy study ever conducted. The landmark study, announced today by Quest Diagnostics Incorporated, the world's leading provider of diagnostic testing, information, and services, includes test results from over 2 million patients.

From Quest Diagnostics 27 May 2011

Research provides new understanding of how heroin affects the brain

New research from the Norwegian Institute of Public Health suggests that our understanding of how heroin affects the brain should be changed. A new report shows that heroin is metabolised to 6-MAM which then crosses the blood-brain barrier to cause the intoxicating effects that arise shortly after heroin administration.

27 May 2011

PolyMedix presents new pre-clinical data on antimicrobial compounds at two scientific meetings

PolyMedix, Inc., an emerging biotechnology company focused on developing new therapeutic drugs to treat life-threatening infectious diseases and acute cardiovascular disorders, announced today that new pre-clinical data for its novel, defensin-mimetic antimicrobial compounds was recently presented at two prestigious scientific meetings, including the American Society of Microbiology.

25 May 2011

Researchers devise new genetic technique for IVF embryos

Researchers at the Johns Hopkins University School of Medicine have devised a new technique, which helps couples that are affected by or are carriers of genetic diseases have in vitro fertilized babies free of both the disease in question and other chromosomal abnormalities. The results were reported in the April issue of Fertility and Sterility.

24 May 2011

Scientific evidence supports benefits of sunscreen usage to prevent skin cancer

The American Academy of Dermatology today reiterated the safety and effectiveness of sunscreens to protect against the damaging effects from exposure to ultraviolet (UV) radiation. As one component of a daily sun-protection strategy, sunscreen is an important tool in the fight against skin cancer, including melanoma, the deadliest form of skin cancer.

24 May 2011

in vitro News and Research

Researchers to use three-dimensional liver mimic for toxicity study on human body

ImaginAb, Oxford BioMedicaplc enter research deal to develop in vivo diagnostic imaging agent

ITI receives FDA clearance for new Q fever assay kit

Genesis Biopharma expands clinical focus to develop Contego for Stage IV metastatic melanoma

Azellon receives MHRA approval to initiate stem cell bandage clinical trial in torn meniscal cartilage

Researcher finds thyroid cancer gene inhibits spread of malignant cells

Anti-Mullerian hormone test can indicate reproductive function in young women with cancer

Additional data supporting utility of PAM50 gene signature for breast cancer to be presented at ASCO 2011

Scientists discover new compound that inhibits bitterness

Clovis Oncology, Roche partner to develop in vitro PCR-based diagnostic test for NSCLC

Investigators to examine how Ephb2 gene causes ependymoma in children

Niiki Pharma to present NKP-1339 Phase I trial against metastatic cancer at ASCO 2011

Pacific Reproductive Center celebrates Annual Baby Reunion in Torrance

New ways to replicate what happens to stents tucked inside blood vessels

Phadia ImmunoCAP Specific IgE blood test used in largest cross-sectional allergy study

Quest Diagnostics announces results of largest ImmunoCAP cross-sectional allergy study

Research provides new understanding of how heroin affects the brain

PolyMedix presents new pre-clinical data on antimicrobial compounds at two scientific meetings

Researchers devise new genetic technique for IVF embryos

Scientific evidence supports benefits of sunscreen usage to prevent skin cancer

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