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Study reveals two enzymes help immune cells deploy pathogen-killing traps

A new study reveals that two enzymes help immune cells deploy pathogen-killing traps by unraveling and using the chromatin (DNA and its associated proteins) contained in the cells' nuclei to form defensive webs. The study appears online on October 25 in The Journal of Cell Biology.

26 Oct 2010

New feature on SciVerse ScienceDirect presents proteins in three dimensions

Elsevier, a world-leading publisher of scientific, medical and technical products and services, introduces Protein Viewer, a new, interactive feature on SciVerse ScienceDirect for the Journal of Molecular Biology (JMB). With Protein Viewer, readers of JMB now have the power to expand and rotate molecules within the actual article. SciVerse ScienceDirect merges features of the World Protein Database and Jmol, and embeds them into the article, making its use more convenient and user-friendly.

26 Oct 2010

Maven Semantic updates Lymphocyte Cell Biology research database

Maven Semantic announces updates to their Lymphocyte Cell Biology research database. The new database is now available to marketing, business development, competitor intelligence, KOL, medical affairs and related departments in the life sciences sector.

26 Oct 2010

ARIAD's oral ridaforolimus improves PFS in patients with metastatic endometrial cancer

Pharmaceuticals, Inc. today announced interim results of a randomized, open‐label, active-control multicenter Phase 2 study of oral ridaforolimus, an investigational mTOR inhibitor, in patients with metastatic or recurrent endometrial cancer. Based on this interim analysis, the study demonstrated a statistically significant improvement in the primary endpoint of median progression-free survival (PFS) in patients receiving single-agent ridaforolimus compared to patients receiving standard-of-care treatment.

26 Oct 2010

Lead exposure may reverse blindness: Research

Some unexpected effects of lead exposure that may one day help prevent and reverse blindness have been uncovered by a University of Houston (UH) professor and his team.

26 Oct 2010

Daily dose of whole body vibration reduces bone density loss

A daily dose of whole body vibration may help reduce the usual bone density loss that occurs with age, Medical College of Georgia researchers report.

25 Oct 2010

Doctations 2.0 EHR system achieves Surescripts Gold Certification and ONC-ATCB 2011/2012 certification

DocPatientNetwork, Inc. announced today that Doctations Version 2.0, its complete internet-based Electronic Health Record (EHR) system, is Surescripts Gold Certified and is a CCHIT Certified 2011 Ambulatory EHR, joining a list of eight to have achieved both certifications. Additionally, DocPatientNetwork is one of only three vendors in the country to achieve Surescripts Gold Certification and ONC-ATCB 2011/2012 certification as a Complete EHR.

25 Oct 2010

Researchers create new high-content assay to increase human embryonic stem cell survival

A new technique for increasing the survival rates of human embryonic stem cells will revolutionize their use in drug discovery and therapy. Human embryonic stem cells often die during the process of isolation using enzymatic disaggregation or low-density plating, which limits their usefulness in drug discovery and basic research. Similarly, the low rate of attachment of implanted cells hinders cell therapy.

25 Oct 2010

Seattle Genetics, Millennium to feature SGN-35 in three poster presentations at ISHL symposium

Seattle Genetics, Inc. and Millennium: The Takeda Oncology Company, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited (TSE:4502), today announced that brentuximab vedotin (SGN-35) will be featured in three poster presentations at the 8th International Symposium on Hodgkin Lymphoma (ISHL) being held October 23-26, 2010 in Cologne, Germany.

25 Oct 2010

GSN initiates trial of microarray PGD on pregnancy and implantation rates in IVF

Gene Security Network (GSN) announced today that it has initiated enrollment for a prospective randomized trial in collaboration with Ferring Pharmaceuticals to evaluate the impact of GSN's advanced preimplantation genetic diagnosis (PGD) with Parental Support™ on pregnancy and implantation rates in IVF.

25 Oct 2010

Soligenix reports Phase 2 clinical trial results of orBec for GVHD

Soligenix, Inc. a late-stage biopharmaceutical company, today reported preliminary results from its Phase 2 "proof-of-concept" exploratory clinical trial of orBec for the prevention of acute Graft-versus-Host disease (GVHD) in patients undergoing myeloablative conditioning regimens with initiation of dosing prior to hematopoietic cell transplantation (HCT) and continuing through the post-transplantation period.

25 Oct 2010

Cryo-Cell to launch new reproductive tissue service for cryopreserved embryos, oocyctes

Cryo-Cell International, Inc. one of the world's largest and most established family cord blood banks and global stem cell innovators, today announced plans at the annual meeting of the American Society of Reproductive Medicine (ASRM) to launch Cryology RTS, a new reproductive tissue storage service for cryopreserved embryos, oocyctes and sperm.

25 Oct 2010

Popular Mechanics recognizes three NSF-funded projects with innovation Breakthrough Awards

Popular Mechanics has recognized three NSF-funded projects with innovation Breakthrough Awards: an artificial retina returning sight to those who have lost it; a system that uses "controlled rocking" and energy-dissipating fuses to help buildings withstand earthquakes; and an inexpensive medical microscope built for cell-phones that allows doctors in rural villages to identify malaria-infected blood cells.

25 Oct 2010

Antigenics expands HSPPC-96 Phase 2 clinical study in glioma

Antigenics, Inc. today announced the expansion of a phase 2 clinical study of HSPPC-96 (Oncophage® vaccine; vitespen), Antigenics' personalized therapeutic cancer vaccine, in patients with newly diagnosed glioma.

25 Oct 2010

Neptune launches Onemia medical food

Neptune Technologies & Bioressources Inc. enters the pharmaceutical market with the launch of Onemia™, the first medical food of Neptune's subsidiary Acasti Pharma Inc.. Only two years since its foundation, Acasti has completed the development and launch of "Onemia™" on October 21, 2010 at the Cardiometabolic Health Congress meeting in Boston.

25 Oct 2010

Biomerix enters distribution agreement with Medline

Biomerix Corporation, a medical technology company developing and manufacturing innovative hernia repair products, today announced that it has entered into an exclusive distribution agreement with Medline Industries, Inc., the nation's largest privately held manufacturer and distributor of medical and surgical products in the United States.

25 Oct 2010

Researchers publish effects of doctor-designed formula against breast cancer

Researchers at Indiana University and Methodist Research Institute have published the dramatic effects of a natural formula against breast cancer. The impressive results are found in the most recent publication of Integrative Cancer Therapies.

25 Oct 2010

HRSA supports Sickle Cell Disease Treatment Demonstration Program with $1.6M award

HRSA has awarded $1.6 million to support the Sickle Cell Disease Treatment Demonstration Program (SCDTDP). The program is designed to establish practice models for the prevention and treatment of sickle cell disease through the coordinated efforts of providers, key stake holders, affected individuals and their families.

25 Oct 2010

FlexBone shows potential replacement for current bone transplantations

With a failure rate as high as 50 percent, bone tissue grafts pose a significant obstacle to orthopedic surgeons attempting to repair complex fractures or large areas of bone loss, such as those often caused by trauma and cancer. Current synthetic substitutes rarely possess the bone-like properties needed for successful grafting and are often difficult for surgeons to manipulate in the operating room. In response to these challenges, researchers at UMass Medical School have developed an easy-to-produce, inexpensive, synthetic bone material called FlexBone.

25 Oct 2010

New gene therapy product reduces plasma cholesterol levels

Amsterdam Molecular Therapeutics (AMT) Holding N.V. a leader in the development of gene based therapies, today announced that its gene therapy product incorporating siRNA sequences into microRNA scaffolds to silence Apolipoprotein B100 (AAV-miApoB) was able to significantly lower plasma cholesterol levels in vivo over a period of 18 weeks. These preliminary results suggest that this approach could lead to a treatment for high cholesterol in humans

25 Oct 2010

Cell News and Research

Study reveals two enzymes help immune cells deploy pathogen-killing traps

New feature on SciVerse ScienceDirect presents proteins in three dimensions

Maven Semantic updates Lymphocyte Cell Biology research database

ARIAD's oral ridaforolimus improves PFS in patients with metastatic endometrial cancer

Lead exposure may reverse blindness: Research

Daily dose of whole body vibration reduces bone density loss

Doctations 2.0 EHR system achieves Surescripts Gold Certification and ONC-ATCB 2011/2012 certification

Researchers create new high-content assay to increase human embryonic stem cell survival

Seattle Genetics, Millennium to feature SGN-35 in three poster presentations at ISHL symposium

GSN initiates trial of microarray PGD on pregnancy and implantation rates in IVF

Soligenix reports Phase 2 clinical trial results of orBec for GVHD

Cryo-Cell to launch new reproductive tissue service for cryopreserved embryos, oocyctes

Popular Mechanics recognizes three NSF-funded projects with innovation Breakthrough Awards

Antigenics expands HSPPC-96 Phase 2 clinical study in glioma

Neptune launches Onemia medical food

Biomerix enters distribution agreement with Medline

Researchers publish effects of doctor-designed formula against breast cancer

HRSA supports Sickle Cell Disease Treatment Demonstration Program with $1.6M award

FlexBone shows potential replacement for current bone transplantations

New gene therapy product reduces plasma cholesterol levels

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From Discovery Biology to ELRIG Chair

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