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Absorption Systems supports Pediatric Praziquantel Consortium led by Merck KGaA

Absorption Systems, a leader in preclinical contract testing of drugs, biologics, and medical devices, announces that it has been subcontracted by the German pharmaceutical company Merck KGaA to work on a new pediatric formulation of praziquantel.

7 Oct 2014

Researchers find potential new way to better control immune-mediated diseases

Researchers at University of California, San Diego School of Medicine have discovered that T-cells - a type of white blood cell that learns to recognize and attack microbial pathogens - are activated by a pain receptor.

6 Oct 2014

Sigma-Aldrich enters into agreement to acquire Cell Marque to better serve IHC customers

Sigma-Aldrich Corporation announced today that it has entered into an agreement to acquire Rocklin, California, based Cell Marque Corporation in a move to strengthen its antibody portfolio and to better serve immunohistochemistry (IHC) customers.

3 Oct 2014

Columbia Laboratories' subsidiary to unveil ROADMAP to Clinical Trials platform at CPhI/ICSE event

Columbia Laboratories, Inc., today announced that its subsidiary, Molecular Profiles Ltd., is set to unveil the ROADMAP to Clinical Trials platform at the annual CPhI/ICSE Worldwide event in Paris next week, which aims to support companies with the rapid development of both standard and complex drug products.

1 Oct 2014

Researchers create new Cas9 animal model for in vivo genome editing experiments

Researchers from the Broad Institute and Massachusetts Institute of Technology have created a new mouse model to simplify application of the CRISPR-Cas9 system for in vivo genome editing experiments.

29 Sep 2014

Lung-MAP, ALCHEMIST clinical trials offer innovative study designs for lung cancer patients

The recent launch of two clinical trials offer innovative study designs for patients with lung cancer. These clinical trials are the direct result of a National Cancer Institute sponsored workshop chaired by Drs. Fred R. Hirsch, Shakun Malik and Claudio Dansky- Ullman, that brought together the NCI Thoracic Malignancies Steering Committee, the US Food and Drug Administration, academicians, clinicians as well as industry and government stakeholders to discuss issues and challenges related to clinical trial design and biomarkers for lung cancer targeted-therapies.

29 Sep 2014

Research: Skin cells from pediatric patients can be used in tissue-engineered pulmonary valves

Researchers have found a way to take a pediatric patient's skin cells, reprogram the skin cells to function as heart valvular cells, and then use the cells as part of a tissue-engineered pulmonary valve.

24 Sep 2014

AIT, BioVendor and SCIENION partner to develop in-vitro diagnostic test for colon cancer

The AIT Austrian Institute of Technology, BioVendor and SCIENION today announced that the three companies will partner on the development of an in-vitro diagnostic test for colon cancer. The innovative test kit shall identify cancer at an early stage based on tumor autoantibody biomarkers.

24 Sep 2014

Mfn2 protein: A future therapeutic target for neuronal death reduction in ischemic stroke

A new study published in the prestigious publication The EMBO Journal shows that the mitochondrial protein Mfn2 may be a future therapeutic target for neuronal death reduction in the late phases of an ischemic stroke.

24 Sep 2014

Viewpoints: Surgery surprise: Out-of-network doctors' bills; consequences of making Medicaid enrollees pay premiums

The New York Times' Elisabeth Rosenthal offered an important lesson in healthcare economics over the weekend that's a must-read for anyone about to undergo a major medical procedure.

24 Sep 2014

Promising new approach for combating colorectal cancer

Scientists at the University of York are working on a promising new approach for tackling colorectal cancer, the second most common cause of cancer-related death.

23 Sep 2014

Curcumin, cancer-inhibiting peptides show promise in slowing progression of mesothelioma

A common Asian spice and cancer-hampering molecules show promise in slowing the progression of mesothelioma, a cancer of the lung's lining often linked to asbestos. Scientists from Case Western Reserve University and the Georg-Speyer-Haus in Frankfurt, Germany, demonstrate that application of curcumin, a derivative of the spice turmeric, and cancer-inhibiting peptides increase levels of a protein inhibitor known to combat the progression of this cancer.

22 Sep 2014

Activation of MMP-9 enzyme leads to behavioral problems connected to chronic stress

Why is it that when people are too stressed they are often grouchy, grumpy, nasty, distracted or forgetful? Researchers from the Brain Mind Institute at EPFL have just highlighted a fundamental synaptic mechanism that explains the relationship between chronic stress and the loss of social skills and cognitive impairment. When triggered by stress, an enzyme attacks a synaptic regulatory molecule in the brain. This was revealed by a work published in Nature Communications.

19 Sep 2014

Rosuvastatin promotes bone growth in mice with achondroplasia symptoms

Skeletal dysplasia is a group of rare diseases that afflict skeletal growth through abnormalities in bone and cartilage. Its onset hits at the fetal stage and is caused by genetic mutations.

18 Sep 2014

Collaborative study takes important step toward finding targeted treatments for bladder cancer

The story of cancer care seems so simple: find the mutated gene that causes cancer and turn it off or fix it. But rarely does a single gene cause cancer. More often, many genes are altered together to drive the disease. So the challenge becomes sorting out which altered genes are the most to blame in which cancers.

16 Sep 2014

Hudson Robotics awarded NIH grant to develop HTS system for in vivo studies of zebrafish

Hudson Robotics, Inc., of Springfield, NJ, in cooperation with Johns Hopkins University, has recently been awarded an NIH grant to develop a commercially viable high-throughput screening (HTS) system for in vivo studies of zebrafish.

15 Sep 2014

New antiseptic agent holds promise for treatment of periodontitis

The study, published in the journal Science and Technology of Advanced Materials, by Shinichi Arakawa and colleagues at Tokyo Medical and Dental University and Japan's National Institute of Advanced Industrial Science and Technology, evaluated the bactericidal activities of ozone nano-bubble water - also known as NBW3 - against the two main bacterial agents that cause periodontitis as well as its toxicity to human oral tissue cells.

15 Sep 2014

in vitro News and Research

Absorption Systems supports Pediatric Praziquantel Consortium led by Merck KGaA

Researchers find potential new way to better control immune-mediated diseases

Sigma-Aldrich enters into agreement to acquire Cell Marque to better serve IHC customers

Columbia Laboratories' subsidiary to unveil ROADMAP to Clinical Trials platform at CPhI/ICSE event

Researchers create new Cas9 animal model for in vivo genome editing experiments

Lung-MAP, ALCHEMIST clinical trials offer innovative study designs for lung cancer patients

Research: Skin cells from pediatric patients can be used in tissue-engineered pulmonary valves

AIT, BioVendor and SCIENION partner to develop in-vitro diagnostic test for colon cancer

Mfn2 protein: A future therapeutic target for neuronal death reduction in ischemic stroke

Viewpoints: Surgery surprise: Out-of-network doctors' bills; consequences of making Medicaid enrollees pay premiums

Promising new approach for combating colorectal cancer

Curcumin, cancer-inhibiting peptides show promise in slowing progression of mesothelioma

Activation of MMP-9 enzyme leads to behavioral problems connected to chronic stress

Rosuvastatin promotes bone growth in mice with achondroplasia symptoms

Collaborative study takes important step toward finding targeted treatments for bladder cancer

Hudson Robotics awarded NIH grant to develop HTS system for in vivo studies of zebrafish

New antiseptic agent holds promise for treatment of periodontitis

New project aims at delivering innovative test to improve safety of chemical products, drugs

Growth factors present in human breast milk may protect against intestinal damage

Abbott technology may help identify severe infections sooner, lower health care costs

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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