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Scientists discover new signalling pathway that controls both obesity and atherosclerosis

A*STAR scientists from the Institute of Molecular and Cell Biology (IMCB) and the Singapore Bioimaging Consortium (SBIC) have discovered a new signalling pathway that controls both obesity and atherosclerosis.

6 Jul 2012

Scientists use antibody injections to rapidly reverse onset of Type I diabetes in mice

Scientists at the University of North Carolina School of Medicine have used injections of antibodies to rapidly reverse the onset of Type I diabetes in mice genetically bred to develop the disease. Moreover, just two injections maintained disease remission indefinitely without harming the immune system.

6 Jul 2012

Scientists discover constant cloud of potent inflammatory molecules surrounding the monocytes

Scientists at the University of East Anglia (UEA) have discovered a 'constant cloud' of potent inflammatory molecules surrounding the cells responsible for diseases such as thickening of the arteries and rheumatoid arthritis.

5 Jul 2012

Study shows cells from different Parkinson’s patients have unique drug responses

Researchers have taken a step toward personalized medicine for Parkinson's disease, by investigating signs of the disease in patient-derived cells and testing how the cells respond to drug treatments.

5 Jul 2012

Eltrombopag can raise blood cell levels in some people with severe aplastic anemia

Eltrombopag, a drug that was designed to stimulate production of platelets from the bone marrow and thereby improve blood clotting, can raise blood cell levels in some people with severe aplastic anemia who have failed all standard therapies.

5 Jul 2012

Neighboring non-cancer cells may contribute to drug resistance

One of cancer's most frightening characteristics is its ability to return after treatment. In the case of many forms of cancer, including the skin cancer known as melanoma, tailored drugs can eradicate cancer cells in the lab, but often produce only partial, temporary responses in patients. One of the burning questions in the field of cancer research has been and remains: how does cancer evade drug treatment?

5 Jul 2012

Scientists identify causative link between oncometabolite and onset of AML

A team of international scientists led by principal investigator Dr. Tak Mak at the Princess Margaret Cancer Centre, University Health Network, has identified a causative link between the product of a mutated metabolic enzyme and the onset of acute myeloid leukemia (AML), one of the most common types of leukemia in adults.

5 Jul 2012

New research approach can help predict the 'tenability' of antibiotics

Research by Wageningen University, part of Wageningen UR, has shown that the development of bacteria with resistance against the antibiotic cefotaxime occurs more often and more predictably than was previously assumed. Bacterial populations were found to have many mutations that increase resistance and therefore have a negative effect on public health.

4 Jul 2012

Geological Society of London, Elsevier win 2012 Getenergy award

Elsevier, a world-leading provider of scientific, medical and technical information products and services, today announced that, together with the Geological Society of London, it has won the award for best Education/Industry Partnership at the 2012 Getenergy awards ceremony.

4 Jul 2012

The Jeffrey Epstein VI Foundation supports Genetic Initiative at CCFA

The Jeffrey Epstein VI Foundation, which actively supports science research, has given substantial support to the Crohn's and Colitis Foundation of America to continue its Genetic Initiative to find a cure for the diseases.

4 Jul 2012

Study examines how cells exploit gene sequences to cope with toxic stress

Toxic chemicals wreak havoc on cells, damaging DNA and other critical molecules. A new study from researchers at MIT and the University at Albany reveals how a molecular emergency-response system shifts the cell into damage-control mode and helps it survive such attacks by rapidly producing proteins that counteract the harm.

4 Jul 2012

Researchers identify mechanism responsible for inhibition of AMPK activity in the hypothalamus

In the complex chain of molecular events that underlie eating behaviors and body weight, the AMP-activated protein kinase (AMPK) enzyme has proven to be a critical link.

4 Jul 2012

UCLA School of Dentistry receives NIH grant to create comprehensive research training program

In recent years, faculty at the UCLA School of Dentistry have been expanding the traditional boundaries of dentistry through groundbreaking multidisciplinary research that has led to major advances in everything from stem cell science to saliva diagnostics. Now, a $5 million grant from the National Institutes of Health's National Institute of Dental and Craniofacial Research will allow the school to continue these pioneering efforts by creating a comprehensive research training program to help cultivate the next generation of dentist-scientists and oral health researchers.

4 Jul 2012

Acute pancreatitis: An interview with Viktor Oskarsson

Acute pancreatitis is an inflammatory disease of the pancreas. The most common symptom is acute abdominal pain, which is often accompanied with nausea and vomiting.

4 Jul 2012

Higher waist circumference, obesity improve health outcomes in heart failure patients

A slim waist and normal weight are usually associated with better health outcomes, but that's not always the case with heart failure patients, according to a new UCLA study.

4 Jul 2012

Researcher discovers how West Nile virus breaks through the tough blood-brain barrier to CNS

Mosquitoes are buzzing once again, and with that comes the threat of West Nile virus. Tom Hobman, a researcher with the Li Ka Shing Institute of Virology in the Faculty of Medicine & Dentistry, is making every effort to put an end to this potentially serious infection.

4 Jul 2012

Epigenetic changes due to methylation play a key role in altering genes in RA

It's not just our DNA that makes us susceptible to disease and influences its impact and outcome. Scientists are beginning to realize more and more that important changes in genes that are unrelated to changes in the DNA sequence itself - a field of study known as epigenetics - are equally influential.

4 Jul 2012

Important insight into association between childhood maltreatment and suicide

Exposure to childhood maltreatment increases the risk for most psychiatric disorders as well as many negative consequences of these conditions. This new study, by Dr. Gustavo Turecki and colleagues at McGill University, Canada, provides important insight into one of the most extreme outcomes, suicide.

4 Jul 2012

Investigators identify cell replacement/tissue repair potential in adult bone marrow stem cells

Researchers from the University of Maryland School of Maryland report promising results from using adult stem cells from bone marrow in mice to help create tissue cells of other organs, such as the heart, brain and pancreas - a scientific step they hope may lead to potential new ways to replace cells lost in diseases such as diabetes, Parkinson's or Alzheimer's.

4 Jul 2012

Tolfenamic acid appears to reduce esophageal tumors

A new study by researchers at MD Anderson Cancer Center Orlando finds that Tolfenamic acid (TA), a non-steroidal anti-inflammatory drug (NSAID), commonly used to relieve pain, inflammation and migraines has now been found to reduce esophageal tumors.

4 Jul 2012

Cell News and Research

Scientists discover new signalling pathway that controls both obesity and atherosclerosis

Scientists use antibody injections to rapidly reverse onset of Type I diabetes in mice

Scientists discover constant cloud of potent inflammatory molecules surrounding the monocytes

Study shows cells from different Parkinson’s patients have unique drug responses

Eltrombopag can raise blood cell levels in some people with severe aplastic anemia

Neighboring non-cancer cells may contribute to drug resistance

Scientists identify causative link between oncometabolite and onset of AML

New research approach can help predict the 'tenability' of antibiotics

Geological Society of London, Elsevier win 2012 Getenergy award

The Jeffrey Epstein VI Foundation supports Genetic Initiative at CCFA

Study examines how cells exploit gene sequences to cope with toxic stress

Researchers identify mechanism responsible for inhibition of AMPK activity in the hypothalamus

UCLA School of Dentistry receives NIH grant to create comprehensive research training program

Acute pancreatitis: An interview with Viktor Oskarsson

Higher waist circumference, obesity improve health outcomes in heart failure patients

Researcher discovers how West Nile virus breaks through the tough blood-brain barrier to CNS

Epigenetic changes due to methylation play a key role in altering genes in RA

Important insight into association between childhood maltreatment and suicide

Investigators identify cell replacement/tissue repair potential in adult bone marrow stem cells

Tolfenamic acid appears to reduce esophageal tumors

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