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UTMB researchers improve existing experimental vaccine for Rift Valley fever virus

University of Texas Medical Branch researchers have significantly improved an existing experimental vaccine for Rift Valley fever virus, making possible the development of a more effective defense against the dangerous mosquito-borne pathogen.

28 Jun 2012

Study suggests new treatment strategy for heart attacks and strokes

A heart attack doesn't just damage heart muscle tissue by cutting off its blood supply, it also sets off an inflammatory cascade that worsens underlying atherosclerosis, actively increasing the risk for a future heart attack. These findings from a study receiving advance online publication in Nature suggest an important new therapeutic strategy for preventing heart attacks and strokes, both of which are caused when atherosclerotic plaques rupture and block important blood vessels.

28 Jun 2012

LUMC oncologist presents survival data for brentuximab vedotin at 17th EHA Congress

A new cancer drug with remarkably few side effects is dramatically improving survival in Hodgkin lymphoma patients who fail other treatments and are nearly out of options.

28 Jun 2012

UH receives federal grants to pursue projects related to prostate cancer, diabetes and obesity

Researchers at the University of Houston (UH) have been awarded more than $862,000 in federal grants to pursue projects related to prostate cancer, diabetes and obesity. The U.S. Department of Defense (DOD) and National Institutes of Health (NIH) will fund two new prostate cancer projects, while a third NIH grant will support diabetes and obesity research in the UH Center for Nuclear Receptors and Cell Signaling (CNRCS).

28 Jun 2012

Intensive early treatment slows down progression of type 2 diabetes

Intensive early treatment of type 2 diabetes slows down progression of the disease by preserving the body's insulin-producing capacity, a UT Southwestern study has shown.

28 Jun 2012

Scientists transplant stem cells from patients with limb-girdle muscular dystrophy into mice

Stem cells from patients with a rare form of muscular dystrophy have been successfully transplanted into mice affected by the same form of dystrophy, according to a new study published today in Science Translational Medicine.

28 Jun 2012

Lack of access to social protections increases mortality rates among low and medium-skilled U.S. workers

Employment policy is also health policy according to a University of British Columbia study that found that workers experienced higher mortality rates if they didn't have access to social protections like employment insurance and unemployment benefits.

28 Jun 2012

Data from Infinity’s IPI-145 pre-clinical study on inflammatory diseases

Infinity Pharmaceuticals, Inc. today reported preclinical data for IPI-145, the company's oral inhibitor of phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma. The data demonstrate potent PI3K-delta and -gamma inhibition in biochemical, cellular and whole blood assays and activity in multiple preclinical models of inflammatory disease, including rheumatoid arthritis and asthma.

28 Jun 2012

Five medicine safety tips for families traveling with young children

With summer here and vacation season underway, the Centers for Disease Control and Prevention (CDC) and Consumer Healthcare Products Association (CHPA) Educational Foundation, in partnership with the PROTECT Initiative, today released five medicine safety tips for families traveling with young children.

28 Jun 2012

Full results from Derma Sciences’ DSC127 Phase 2 trial on diabetic foot ulcers

Derma Sciences, Inc., a medical device and pharmaceutical company focused on advanced wound care, today announced that full results from its successful Phase 2 clinical trial with the investigational drug DSC127 in patients with diabetic foot ulcers will be published on July 5th in the July 2012 issue of Wound Repair and Regeneration.

28 Jun 2012

Scientists reverse diabetes in mice using stem cells

University of British Columbia scientists, in collaboration with an industry partner, have successfully reversed diabetes in mice using stem cells, paving the way for a breakthrough treatment for a disease that affects nearly one in four Canadians.

28 Jun 2012

Anthera announces results from blisibimod Phase 2b study on SLE

Anthera Pharmaceuticals, Inc., a biopharmaceutical company developing drugs to treat serious diseases associated with inflammation and autoimmune disorders, today announced results from the Phase 2b PEARL-SC clinical study in patients with systemic lupus erythematosus.

28 Jun 2012

Protein kinase A activated in the nucleus as well as the cytoplasm

Using a new tool allowing proteins in a living cell to be manipulated in real time, researchers at Johns Hopkins have stumbled across the answer to a longstanding debate about where and how a certain protein is turned on in the cell. Reporting in the February 2012 issue of Nature Chemical Biology, scientists show that protein kinase A is also activated in the nucleus rather than inside the cell’s body, a challenge to traditional beliefs.

27 Jun 2012

Second potential immune checkpoint target for cancer immunotherapy announced by Compugen

Compugen Ltd. (NASDAQ: CGEN) announced today results demonstrating the therapeutic potential of CGEN-15022, a Compugen-discovered B7/CD28-like membrane protein, as an immune checkpoint target for treatment of multiple cancers.

27 Jun 2012

Federal government makes $13 billion in duplicative payments to veterans

A new study published today in the Journal of the American Medical Association (JAMA) found that the federal government made about $13 billion in duplicative payments to provide health-care services to veterans who were simultaneously enrolled in Medicare Advantage plans from 2004-2009.

27 Jun 2012

Magnet guides iron-loaded cells to specific damaged sites in the heart

Optimal stem cell therapy delivery to damaged areas of the heart after myocardial infarction has been hampered by inefficient homing of cells to the damaged site. However, using rat models, researchers in France have used a magnet to guide cells loaded with iron oxide nanoparticles to key sites, enhancing the myocardial retention of intravascularly delivered endothelial progenitor cells.

27 Jun 2012

Small coils activate neurons to modulate brain-cell activity

Magnetic fields generated by microscopic devices implanted into the brain may be able to modulate brain-cell activity and reduce symptoms of several neurological disorders.

27 Jun 2012

DHA and curcumin help maintain neurological function after degenerative damage

UCLA researchers discovered that a diet enriched with a popular omega-3 fatty acid and an ingredient in curry spice preserved walking ability in rats with spinal-cord injury. Published June 26 in the Journal of Neurosurgery: Spine, the findings suggest that these dietary supplements help repair nerve cells and maintain neurological function after degenerative damage to the neck.

27 Jun 2012

Gene transfer technique eliminates specific neural circuit linked to Parkinson's disease

In the brains of humans and non-human primates, over 100 billion nerve cells build up complicated neural circuits and produce higher brain functions. When an attempt is made to perform gene therapy for neurological diseases like Parkinson's disease, it is necessary to specify a responsible neural circuit out of many complicated circuits.

27 Jun 2012

Diet enriched with curcumin and DHA can promote neuroprotection in chronic SCI

Researchers from the Department of Neurosurgery at the David Geffen School of Medicine and the Department of Integrative Biology and Physiology at UCLA have found that a diet enriched with docosahexaenoic acid (DHA), an omega-3 fatty acid, and curcumin, a component of the Indian spice turmeric, can protect the injured spinal cord and minimize the clinical and biochemical effects of spinal cord myelopathy in rats.

27 Jun 2012

Cell News and Research

UTMB researchers improve existing experimental vaccine for Rift Valley fever virus

Study suggests new treatment strategy for heart attacks and strokes

LUMC oncologist presents survival data for brentuximab vedotin at 17th EHA Congress

UH receives federal grants to pursue projects related to prostate cancer, diabetes and obesity

Intensive early treatment slows down progression of type 2 diabetes

Scientists transplant stem cells from patients with limb-girdle muscular dystrophy into mice

Lack of access to social protections increases mortality rates among low and medium-skilled U.S. workers

Data from Infinity’s IPI-145 pre-clinical study on inflammatory diseases

Five medicine safety tips for families traveling with young children

Full results from Derma Sciences’ DSC127 Phase 2 trial on diabetic foot ulcers

Scientists reverse diabetes in mice using stem cells

Anthera announces results from blisibimod Phase 2b study on SLE

Protein kinase A activated in the nucleus as well as the cytoplasm

Second potential immune checkpoint target for cancer immunotherapy announced by Compugen

Federal government makes $13 billion in duplicative payments to veterans

Magnet guides iron-loaded cells to specific damaged sites in the heart

Small coils activate neurons to modulate brain-cell activity

DHA and curcumin help maintain neurological function after degenerative damage

Gene transfer technique eliminates specific neural circuit linked to Parkinson's disease

Diet enriched with curcumin and DHA can promote neuroprotection in chronic SCI

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