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Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding the cellular and molecular mechanisms of brain development and how they factor into both health and disease.

1 Nov 2022

BCRF renews funding to support the development of novel therapeutics for triple-negative breast cancer

The Breast Cancer Research Foundation (BCRF) has renewed its funding to Elisa Port, MD, and Hanna Irie, MD, PhD, to study new therapeutic approaches that target aggressive triple-negative breast cancer.

31 Oct 2022

Study calls for stronger awareness and control of vascular risk factors leading to stroke

Researchers at the Stroke Research and Prevention Group (HKU Stroke), Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) found that the incidence of 'young stroke' (strokes occurring in individuals aged 18 to 55 years) has increased by 30% in Hong Kong from 2001 to 2021, thus called for better control of vascular risk factors, in particular hypertension.

31 Oct 2022

Study finds persistent disparities in access to prenatal care among pregnant people

Immigrant pregnant people faced persistent inequities in obtaining timely prenatal care as compared with native-born pregnant people in the United States over an eight-year period, a factor that could be contributing to longstanding health disadvantages, according to an analysis published in JAMA Network Open on October 28.

28 Oct 2022

Allostatic load may explain racial disparities in stroke outcomes

Ahead of World Stroke Day, Oct. 29, investigators from the Department of Neurology at Cedars-Sinai have new information on stroke-related health disparities.

28 Oct 2022

FLASH radiotherapy may hold promise as a potential treatment for tough-to-kill tumors

FLASH radiation treatment – which delivers therapeutic doses of radiation in a fraction of a second – may hold promise as a potential treatment for tough-to-kill tumors, a first-in-human study in a small number of people with bone cancer suggests.

24 Oct 2022

New research could have major implications for minimally invasive, robotically delivered brain surgery

The early-stage research tested the delivery and safety of the new implantable catheter design in two sheep to determine its potential for use in diagnosing and treating diseases in the brain.

21 Oct 2022

Henry Ford Hospital earns three-year accreditation from National Accreditation Program for Rectal Cancer

Henry Ford Hospital has earned a three-year accreditation from the National Accreditation Program for Rectal Cancer (NAPRC), which was developed through a collaboration between the OSTRiCh (Optimizing the Surgical Treatment of Rectal Cancer) consortium and the Commission on Cancer, a quality program of the American College of Surgeons.

20 Oct 2022

Immune-suppressing drug reverses symptoms of delirium in mice

Investigators from the departments of Neurology, Neurosurgery, Psychiatry, Medicine, and Biomedical Sciences at Cedars-Sinai have shown that an immune-suppressing drug similar to one used to treat severe COVID-19 reversed symptoms of delirium in mice whose lungs were injured during mechanical breathing assistance.

19 Oct 2022

Penn State researchers lay the foundation for precision fabrication of tumor models

Researchers at Penn State have successfully 3D bioprinted breast cancer tumors and treated them in a breakthrough study to better understand the disease that is one of the leading causes of mortality worldwide.

18 Oct 2022

Researchers identify a new gene essential to colon cancer growth

Researchers at Mount Sinai's Tisch Cancer Institute have identified a new gene that is essential to colon cancer growth and found that inflammation in the external environment around the tumor can contribute to the growth of tumor cells.

17 Oct 2022

New tissue clearing method simplifies and speeds up the process to make organs transparent for imaging

The adage 'Seeing is believing' was front of mind for Dr. Chih-Wei Logan Hsu and Dr. Joshua D. Wythe at Baylor College of Medicine as they and their colleagues developed an innovative technology called EZ Clear.

13 Oct 2022

FUSCLEAN technology enables preventive cleaning of catheters and valves in patients with hydrocephaly

Researchers at the University of Seville and University Hospital Virgen del Rocío have published the results of the first successful test of a new technology created to prevent obstructions in catheters and valves (shunts) implanted in the brain of patients with hydrocephalus.

12 Oct 2022

Inflammation and infection may predict post-thrombectomy mortality

In a new study, researchers assessed the association of markers of inflammation and infection with mortality in individuals with acute ischemic stroke post-thrombectomy.

12 Oct 2022

USF researchers test a protein that shows potential as novel therapeutic for ALS patients

Researchers at the USF Health Morsani College of Medicine, located at the University of South Florida, successfully tested a protein that has the potential to aid in the development of a protein-based therapy for patients with ALS, a progressive nervous system disease, also known as Lou Gehrig's disease, that affects nerve cells in the brain and spinal cord.

7 Oct 2022

Mount Sinai study suggests significant role of reactive oxygen species in maintaining healthy intestines

Mount Sinai researchers have published one of the first studies to demonstrate the importance of reactive oxygen species in maintaining stem cell function and preventing inflammation during wound repair, which could provide greater insights into the prevention and treatment of inflammatory bowel diseases (IBD), according to findings published in the journal Gut on October 3.

3 Oct 2022

Neurosurgery News and Research

Study provides more nuanced insights into RNA modifications by A-to-I editing during brain development

BCRF renews funding to support the development of novel therapeutics for triple-negative breast cancer

Study calls for stronger awareness and control of vascular risk factors leading to stroke

Study finds persistent disparities in access to prenatal care among pregnant people

Allostatic load may explain racial disparities in stroke outcomes

FLASH radiotherapy may hold promise as a potential treatment for tough-to-kill tumors

New research could have major implications for minimally invasive, robotically delivered brain surgery

Henry Ford Hospital earns three-year accreditation from National Accreditation Program for Rectal Cancer

Immune-suppressing drug reverses symptoms of delirium in mice

Penn State researchers lay the foundation for precision fabrication of tumor models

Researchers identify a new gene essential to colon cancer growth

New tissue clearing method simplifies and speeds up the process to make organs transparent for imaging

FUSCLEAN technology enables preventive cleaning of catheters and valves in patients with hydrocephaly

Inflammation and infection may predict post-thrombectomy mortality

USF researchers test a protein that shows potential as novel therapeutic for ALS patients

Mount Sinai study suggests significant role of reactive oxygen species in maintaining healthy intestines

Deep brain stimulation as obsessive-compulsive disorder treatment

Mount Sinai researchers use unbiased AI-based method to study the causes of cognitive impairment

Duke University Hospital selected as Center of Excellence for treating cerebral cavernous malformations

New radiation therapy option may extend lifespan, improve quality of life for certain brain cancer patients

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