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Seattle Genetics completes enrollment of its pivotal clinical trial of brentuximab vedotin

Seattle Genetics, Inc. today announced that it has completed enrollment of its pivotal clinical trial of brentuximab vedotin (SGN-35) for relapsed and refractory Hodgkin lymphoma. Brentuximab vedotin is an antibody-drug conjugate (ADC) targeted to CD30 utilizing the company’s proprietary ADC technology.

25 Aug 2009

Microbiologists discover new therapies for human respiratory syncytial virus and influenza A virus

A cellular molecule that not only can sense two common respiratory viruses but also can direct cells to mount a defense has been identified by microbiologists at The University of Texas Health Science Center at San Antonio.

24 Aug 2009

Lancet examines dengue fever in Mexico

Lancet World Report examines the factors contributing to a steady uptick in the number of dengue fever cases in Mexico over the past decade. Compared to the year 2000, when "there were 1,781 reported cases … Last year, the number totalled 33,000, according to Mexico's Public Health Department. And confirmed cases this year have already surpassed 2008 figures by 15%," according to the journal.

24 Aug 2009

FDA approves Hiberix Haemophilus influenzae type b vaccine

In response to a U.S. shortage of a vaccine to protect infants from Haemophilus influenzae type b (Hib), GlaxoSmithKline (NYSE: GSK) has received accelerated approval from the FDA (Food and Drug Administration) for Hiberix((R)) [Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate)] as a booster dose in children 15 months through four years of age. Hib is an often severe and potentially deadly bacterial infection that can cause meningitis.

19 Aug 2009

Common-sense precautions for H1N1

Doctors and hospitals nationwide expect a surge in H1N1 influenza cases during the upcoming flu season. In a new video and the tips below, Yvonne Maldonado, MD, chief of infectious disease at Lucile Packard Children’s Hospital at Stanford, explains what every parent should know about H1N1 flu as children head back to school.

19 Aug 2009

New guidance on novel H1N1 influenza for K-12 schools

The Secretary of Health today released guidance on Novel H1N1, also known as swine flu, for elementary and secondary schools in an effort to keep kids and staff healthy and flu-free this school year.

17 Aug 2009

Pennsylvania's first case of West Nile in 2009 confirmed

State Health Secretary Everette James today reported this year's first confirmed human case of West Nile virus in Pennsylvania. The individual is a 21-year-old woman from Luzerne County.

12 Aug 2009

New insights into identifying children at risk for autoimmune brain disorders

A new study by researchers at Columbia University Mailman School of Public Health's Center for Infection and Immunity indicates that pediatric obsessive-compulsive disorder (OCD), Tourette syndrome and/or tic disorder may develop from an inappropriate immune response to the bacteria causing common throat infections.

11 Aug 2009

Updated Federal Guidelines for 2009 H1N1 influenza in schools

Updated federal guidelines offer state and local public health and school officials a range of options for responding to 2009 H1N1 influenza in schools, depending on how severe the flu may be in their communities.

7 Aug 2009

Tips to avoid heat stroke

The first sign of dangerous heat stroke can be just that – no sweat. As the temperature rises, your body’s natural cooling mechanism, sweat (or more kindly, perspiration), evaporates and helps to cool your body. But on those hot, humid cut-the-air-with-a knife days, evaporation is slowed and your body may not be able to keep itself cool.

5 Aug 2009

Washington Post examines health toll of Congo conflict

The Washington Post examines the devastating toll the conflict in the Congo has had on the health of the country's displaced civilians, as told through the death of a 36-year-old farmer, who succumbed to typhoid fever far away from the home he abandoned.

3 Aug 2009

Colchicine approved for acute gout, Mediterranean fever

The U.S. Food and Drug Administration has approved Colcrys to treat acute flairs in patients with gout, a recurrent and painful form of arthritis, and patients with familial Mediterranean fever (FMF), an inherited inflammatory disorder. The medication's active ingredient is colchicine, a complex compound derived from the dried seeds of a plant known as the autumn crocus or meadow saffron (Colchicum autumnale).

30 Jul 2009

H1N1 death toll doubles over last month; first vaccine trial begins

The worldwide death toll from the H1N1 (swine flu) virus has doubled in the past month, reaching over 700, the WHO announced Tuesday, the AP/Google.com reports.

22 Jul 2009

Researchers expose the biology of Clostridium difficile transmission in mice

New research suggests that antibiotic treatment could be asymptomatically inducing the transmission of the healthcare-acquired infection, C. difficile, contributing to the outbreaks that have recently been widely reported in hospitals and other settings. A team of scientists have successfully mirrored the infection cycle of C. difficile by generating a 'mouse hospital' with conditions mimicking the human environment in which C. difficile is transmitted.

20 Jul 2009

Developed countries must address global warming to prevent disease, hunger in developing world

Pollution from the world's wealthiest countries is spreading disease and hunger in developing countries, according to a new Oxfam International report, which calls on developed countries to address global warming when G8 leaders meet in Italy, the Globe and Mail reports.

7 Jul 2009

Communicable disease epidemics in developing world not being adequately addressed, IFRC says

The "crippling" and "growing burden" of communicable diseases such as dengue fever, polio, or meningitis is not being sufficiently addressed in developing countries, according to "The Epidemic Divide," a report released Monday by the International Federation of Red Cross and Red Crescent Societies (IFRC), AFP/Google.com reports. According to the report, resources to deal with existing epidemics are "scarce."

7 Jul 2009

Warnings about ‘over-use’ of paracetamol

A panel of experts in the United States has raised new concerns about the popular painkiller paracetamol and are calling for the Food and Drug Administration (FDA) to reduce the maximum dose of paracetamol allowed because they say 'over-use' can cause serious liver damage.

5 Jul 2009

Newsweek, Boston Globe examine ways to combat mosquito-borne illness

Newsweek examines the genetic modification of mosquitoes in an effort to stem the spread of dengue fever and malaria. Dengue fever, which is transmitted by the Aedes Aegypti mosquito, "is spreading fast," according to the magazine, with more than 100 million people afflicted yearly. "There is no vaccine, no cure and no solution," it reports.

30 Jun 2009

Gene expression differences could bring better classification and treatment of juvenile arthritis

Scientists have discovered gene expression differences that could lead to better ways to classify, predict outcome, and treat juvenile idiopathic arthritis (JIA). Eventually such findings could enable doctors to target more aggressive treatment to children at risk of more severe arthritis, while those likely to have milder disease could be spared the stronger treatments that carry a greater risk of side effects. The researchers were supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health.

29 Jun 2009

VOA News examines malaria in southern Sudan

VOA News examines malaria in southern Sudan. In the region, malaria is "widespread" and accounts for "up to 30 percent of all diseases treated by health facilities." It is the "number one killer of children in southern Sudan," though there are "no reliable statistics on the number in southern Sudan who suffer, or die from, malaria," VOA News reports.

29 Jun 2009