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Breakthrough technology enables mRNA delivery across the blood-brain barrier

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature of the blood-brain barrier.

17 Feb 2025

Diabetes drugs may boost brain health but experts warn of risks

Researchers reviewed 374 studies to explore how GLP-1RAs, originally for diabetes, may impact brain health, finding potential benefits for dementia and addiction but inconsistent results for mood disorders.

16 Feb 2025

New research sheds light on brain inflammation in Alzheimer's

Brain inflammation, while a crucial part of the body's immune response, takes on a detrimental role in Alzheimer's disease.

16 Feb 2025

Prozac's surprising immune-boosting effects could lead to new treatments for sepsis

Antidepressants like Prozac are commonly prescribed to treat mental health disorders, but new research suggests they could also protect against serious infections and life-threatening sepsis.

14 Feb 2025

Innovative blood test shows potential to replace spinal tap for Alzheimer's diagnosis

Up to half of all people living with Alzheimer's Disease in Ireland remain undiagnosed. Now, a new blood test may have the potential to transform patient care, allowing for better diagnosis, earlier interventions and more targeted treatments.

14 Feb 2025

Sotagliflozin could be used to reduce the risk of deadly cardiovascular events, trial shows

Sotagliflozin, a drug recently approved by the Food and Drug Administration to treat type 2 diabetes and kidney disease with additional cardiovascular risk factors, can significantly reduce heart attack and stroke among these patients, according to results from an international clinical trial led by a Mount Sinai researcher.

14 Feb 2025

Urgent CDC data and analyses on influenza and bird flu go missing as outbreaks escalate

Sonya Stokes, an emergency room physician in the San Francisco Bay Area, braces herself for a daily deluge of patients sick with coughs, soreness, fevers, vomiting, and other flu-like symptoms.

14 Feb 2025

Intracranial hemorrhages linked to higher dementia risk

Weill Cornell Medicine researchers have found that intracranial hemorrhages, or "brain bleeds" caused by a ruptured blood vessel in the brain, double a person's risk of developing dementia later in life.

14 Feb 2025

Intermittent fasting may harm insulin-producing cells in teens

A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers from Technical University of Munich (TUM), LMU Hospital Munich, and Helmholtz Munich discovered that chronic intermittent fasting disrupted the development of insulin-producing beta cells in young mice.

14 Feb 2025

Atherosclerosis detection in lung cancer patients through CT scans

Several cardiovascular risk factors, such as advanced age and smoking history, are prevalent among lung cancer patients at the time of the diagnosis and increase their risk of future heart disease, according to a new study being presented at ACC's Advancing the Cardiovascular Care of the Oncology Patient course.

14 Feb 2025

A step toward precision medicine: New drug targets for heart failure

Researchers identify several promising drug targets for heart failure and its clinical subtypes.

14 Feb 2025

Risk of bleeding with blood thinners reduces over time

Blood thinners prescribed after blood clots in leg or lung initially increase the risk of bleeding, especially in women and elderly.

14 Feb 2025

Researchers uncover cause of persistent blood clots despite treatment

A team of researchers have made a new discovery in the field of hematology, providing an explanation for spontaneous and unusual blood-clotting that continues to occur despite treatment with full-dose blood thinners.

14 Feb 2025

IgG-guided diet outperforms sham diet in clinical trial

Michigan Medicine and Cleveland Clinic researchers have found that patients with irritable bowel syndrome were more likely to experience less abdominal pain if they followed a diet guided by the results of a blood test, compared to those who followed a sham elimination diet.

13 Feb 2025

Rethinking red meat: Are dietary guidelines missing the bigger picture?

Research highlights the critical role of red meat in providing essential nutrients like iron, zinc, and B12, particularly for vulnerable populations, while questioning the low-certainty evidence linking it to chronic diseases. It urges policymakers to balance health, environmental, and economic factors when considering dietary guidelines.

13 Feb 2025