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KYTHERA commences two ATX-101 Phase III trials for reduction of submental fat

KYTHERA Biopharmaceuticals, Inc., a privately-held biotechnology company focused on the development and commercialization of prescription products in aesthetic medicine, today announced the initiation of two pivotal U.S. Phase III trials of ATX-101, a first-in-class injectable drug under clinical investigation for the reduction of submental (under the chin) fat.

5 Mar 2012

Inovio's SynCon vaccine for HPV types 6 and 11 induces CD8+ T cells in mice

Inovio Pharmaceuticals, Inc. announced today that its SynCon therapeutic vaccine for human papillomavirus (HPV) types 6 and 11, which are associated with head & neck cancers and genital warts, among other conditions, induced strong antigen-specific CD8+ T cells in mice.

5 Mar 2012

IDS, AADA disappointed in postponement of vote by Idaho on indoor tanning bed legislation

The Idaho Dermatology Society (IDS) and the American Academy of Dermatology Association (AADA) are disappointed in the postponement of the vote by the Idaho House of Representatives on House Bill 486, which would ban the use of indoor tanning beds by minors under the age of 18.

5 Mar 2012

Bovine collagen can enhance gum healing

Receding gums often result in tooth sensitivity and can lead to decay of the root and persistent inflammation of the gum. New research published in BioMed Central's open access journal Head & Face Medicine demonstrates that a novel method using bovine collagen is able to enhance gum healing. This resulted in thicker margins around the tooth and, in over half the cases, complete coverage of exposed roots.

5 Mar 2012

Scientists discover how to enhance production of hepatocytes to repair damaged liver tissue

Scientists have shed light on how the liver repairs itself with research that could help develop drugs to treat liver disease.

4 Mar 2012

Novel partnership could transform breast cancer diagnosis

An innovative University of Sydney research partnership with private enterprise could see a radical change in how breast cancer is diagnosed, with the possibility to improve detection rates.

4 Mar 2012

Deficits in mirror neuron system contribute to social impairments in ASD

Impaired social function is a cardinal symptom of autism spectrum disorders (ASDs). One of the brain circuits that enable us to relate to other people is the "mirror neuron" system. This brain circuit is activated when we watch other people, and allows our brains to represent the actions of others, influencing our ability to learn new tasks and to understand the intentions and experiences of other people.

3 Mar 2012

New APS policy requires reporting of sex and gender in experimental studies

The American Physiology Society (APS) has announced a new policy requiring the reporting of the sex of experimental animals and the sex or gender of humans used in studies submitted for publication in any of the organization's 13 peer-reviewed journals.

3 Mar 2012

Rigosertib drug shows promise against advanced pancreatic cancer

The American Cancer Society estimates that 44,000 new cases of pancreatic cancer will be diagnosed this year and that 37,000 people will die from the disease. These are not strong odds. A new drug, rigosertib, allows pancreatic cancer cells to rush through replication - and then stops them cold, killing them in in the middle of a step called M phase. Healthy cells that don't rush are unharmed.

3 Mar 2012

R-loop formation may drive under-methylation and autoimmunity

Researchers at the University of California, Davis, have figured out how the human body keeps essential genes switched "on" and silences the vast stretches of genetic repeats and "junk" DNA.

3 Mar 2012

Ion channels assembled in different combinations distinguish temperatures

The winter sun feels welcome, but not so a summer sunburn. Research over the past 20 years has shown that proteins on the surface of nerve cells enable the body to sense several different temperatures. Now scientists have discovered how just a few of these proteins, called ion channels, distinguish perhaps dozens of discrete temperatures, from mildly warm to very hot.

3 Mar 2012

Researchers identify mechanism by which cannabis affects working memory

A deterioration of working memory is observed in people who consume drugs containing cannabinoid compounds found in cannabis leaves and buds. A team led by Giovanni Marsicano in collaboration with a team led by Xia Zhang, has recently identified the mechanism by which these substances affect working memory.

3 Mar 2012

New breakthrough in early mammalian embryo development

Pioneering work by a leading University of Nottingham scientist has helped reveal for the first time a vital process in the development of the early mammalian embryo.

3 Mar 2012

Union County Commission honors KF scientist with Women of Excellence Award

Helen Genova, PhD, research scientist at Kessler Foundation, received a Women of Excellence Award in Health Sciences from the Union County Commission on the Status of Women. In the Foundation's Neuropsychology and Neuroscience Laboratory, she investigates the effects of multiple sclerosis (MS) and traumatic brain injury on cognitive function with grant funding.

3 Mar 2012

REST molecule acts as an adapter in stem cells, times neuronal development

Upon fertilisation, a single cell is formed when egg and sperm fuse. Our entire body, with more than 200 specialised cell types and billions of cells are formed from this single cell. It is a scientific mystery how the early stem cells know what cell type to become, but a precise timing of the process is crucial for correct development and function of our body.

3 Mar 2012

Scientists to develop new carbon-based biointerfaces

In the future, neural implants could replace destroyed sensory cells in the eye or ear - a dream come true for humanity. One of the greatest challenges yet to be addressed is designing the interface between medical technology and human tissue. In order to overcome the limitations of existing models, scientists from Forschungszentrum Juelich and eleven other institutions involved in the NeuroCare project, which kicked off on 1 March 2012, will develop novel biointerfaces made of carbon.

3 Mar 2012

Critical new details about structure of enterovirus 71

Researchers have discovered critical new details about the structure of a virus that causes potentially fatal brain swelling and paralysis in children, pointing toward designs for antiviral drugs to treat the disease.

3 Mar 2012

CLR01 blocks toxic aggregations of proteins in mouse model of Parkinson's

Millions of people suffer from Parkinson's disease, a disorder of the nervous system that affects movement and worsens over time. As the world's population ages, it's estimated that the number of people with the disease will rise sharply. Yet despite several effective therapies that treat Parkinson's symptoms, nothing slows its progression.

2 Mar 2012

New way to culture stem cells in 3D environment

Stem cells are the body's mechanics, repairing damaged tissues and organs. Because these cells are able to grow into any type of cell in the body, scientists believe they hold the key to groundbreaking new therapies. To help further this research, scientists from the University of Victoria have found a new way to culture cells in 3D- a significant step forward for regenerative medicine.

2 Mar 2012

EC grants marketing authorization for Baxter's VEPACEL to treat influenza A

Baxter International Inc. announced today that the European Commission (EC) has granted marketing authorization for VEPACEL in all European Union (EU) Member States, as well as Iceland, Liechtenstein and Norway.

From Baxter International Inc. 2 Mar 2012