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UNIGE discovers new class of molecules toxic for Plasmodium pathogen

The malaria parasite is particularly pernicious since it is built to develop resistance to treatments. The lack of new therapeutic approaches also contributes to the persistence of this global scourge.

12 Mar 2014

Promethera Biosciences, EMD Millipore partner to develop ready-to-use microfluidic perfusion liver assay

Promethera Biosciences, a company that develops innovative therapies for the treatment of liver diseases, today announces a collaboration with EMD Millipore to develop an improved ready-to-use microfluidic perfusion liver assay. This new product is designed to perform more robust studies in pre-clinical toxicity and drug metabolism.

11 Mar 2014

Homologous recombination technology for research applications in genetically modified rodents: an interview with Alexandre Fraichard, CEO, genOway

Homologous recombination is a technology that enables the targeted insertion of nucleotide fragments into the genome of a cell. It is called ‘homologous’ because it uses a sequence that is a homologue to the sequence being targeted in a gene, so that the sequence is recognized.

10 Mar 2014

Tubulin protein is a well-validated cancer drug target

Tubulin, the building-block protein of cellular microtubules, is a well-validated cancer drug target: Disrupting tubulin polymerization affects cytoskeletal function and thus cell division.

10 Mar 2014

ThromboGenics receives IWT grant to study potential new biotherapeutics for DME

ThromboGenics NV, an integrated biopharmaceutical company focused on developing and commercializing innovative ophthalmic medicines for the back of the eye, today announces that it has been awarded a €3 million grant from the Flemish agency for Innovation by Science and Technology.

10 Mar 2014

Metallic toys, low-cost jewelry can affect children's health

We know that babies and young children often put non-food items in their mouths, a behaviour that occasionally leads to swallowing of foreign objects. Metallic toys and low-cost jewelry often contain toxic substances such as lead and cadmium.

6 Mar 2014

New study shows male hormones play important role; may enhance IVF therapy in women

Several fertility clinics across the country are beginning to administer testosterone, either through a patch or a gel on the skin, to increase the number of eggs produced by certain women undergoing in vitro fertilization (IVF).

5 Mar 2014

Plymouth University enters partnership with Brain Tumour Research

Patients, carers, scientists, clinicians and charities from across the UK are heading to Westminster today for the launch of a ground-breaking new collaborative partnership between the charity Brain Tumour Research and Plymouth University Peninsula Schools of Medicine and Dentistry. The announcement will open a new chapter in long-term sustainable and continuous research into the biggest cancer killer of children and adults under 40.

5 Mar 2014

$Researchers develop silk-based surgical plates and screws to repair bone fractures$

Researchers develop silk-based surgical plates and screws to repair bone fractures

When a person suffers a broken bone, treatment calls for the surgeon to insert screws and plates to help bond the broken sections and enable the fracture to heal. These "fixation devices" are usually made of metal alloys.

5 Mar 2014

Plymouth becomes active research partner with Brain Tumour Research

Plymouth University Peninsula Schools of Medicine and Dentistry will now become an active research and fundraising partner with Brain Tumour Research. The charity will support research and supply dedicated members of staff with expertise in fundraising, marketing and PR to work at both local and national levels alongside existing teams, creating a dynamic fundraising programme.

5 Mar 2014

Bruker opens new preclinical imaging center of excellence for the Americas

Bruker (NASDAQ: BRKR) today announced the official opening of a new Preclinical Imaging Center of Excellence for the Americas in Billerica, Massachusetts. The facility offers advanced development, demonstration and support facilities for Bruker’s industry-leading portfolio of preclinical imaging instrumentation and multimodal platforms.

4 Mar 2014

Procellera technology enhances cell migration in in-vitro laboratory testing

Procellera – the world's first wireless microcurrent generating dressing that produces electrical fields through its matrix of microcell batteries – was found to significantly enhance cell migration in in-vitro laboratory testing, according to groundbreaking research led by The Ohio State University Wexner Medical Center Professor Chandan K. Sen. Professor Sen is also the Director of the Comprehensive Wound Center at Ohio State.

4 Mar 2014

A-PARADDISE consortium obtains funds to develop innovative therapies for neglected parasitic diseases

The international consortium A-PARADDISE (Anti-Parasitic Drug Discovery in Epigenetics), coordinated by Inserm, has just obtained funds of €6 million from the European Commission to conduct large-scale testing of innovative therapies against four neglected parasitic diseases: schistosomiasis, leishmaniasis, Chagas disease and malaria.

4 Mar 2014

Mindray's net revenues increase 16.5% to $368.4 million in fourth quarter 2013

Mindray Medical International Limited, a leading developer, manufacturer and marketer of medical devices worldwide, announced today its selected unaudited financial results for the fourth quarter and full year ended December 31, 2013.

From Mindray 4 Mar 2014

Hypervirulent S. pneumoniae mutants discovered

Swedish researchers studying Streptococcus pneumoniae have discovered “hypervirulent” mutant forms of the bacteria that are selected for because they are more resistant to clearance by macrophages.

3 Mar 2014

New methodology for rapid detection of antibiotics in blood paves way to drug development, personalized treatment

A new methodology for rapidly measuring the level of antibiotic drug molecules in human blood serum has been developed, paving the way to applications within drug development and personalised medicine.

3 Mar 2014

H4 receptor activation plays part in NSCLC progression

Histamine H4 receptor activation decreases epithelial-to-mesenchymal transmission in non-small-cell lung cancer, Chinese research shows.

27 Feb 2014

Researchers identify novel strategies to develop more efficient vaccines against encapsulated bacteria

Researchers have discovered the presence of a novel subtype of innate lymphoid cells in human spleen essential for the production of antibodies. This discovery, published in the prestigious journal Nature Immunology, clears the path to the identification of novel strategies to develop more efficient vaccines against encapsulated bacteria, considered highly virulent.

24 Feb 2014

Scientists propose improved method of screening salmonella vaccines in small animal studies

An innovative vaccine technology makes use of reengineered salmonella to deliver protective immunity. If such recombinant attenuated salmonella vaccines or RASVs can be perfected, they hold the promise of safe, lost-cost, orally administered defenses against viral, bacterial, fungal and parasitic infections.

19 Feb 2014

Researchers present new drug candidate that selectively kills cancer cells through starvation

In a study published in Nature Communications, researchers at Karolinska Institutet and Uppsala University in Sweden present a new drug candidate, which selectively kills dormant cells within a cancer tumour through starvation.

19 Feb 2014

in vitro News and Research

UNIGE discovers new class of molecules toxic for Plasmodium pathogen

Promethera Biosciences, EMD Millipore partner to develop ready-to-use microfluidic perfusion liver assay

Homologous recombination technology for research applications in genetically modified rodents: an interview with Alexandre Fraichard, CEO, genOway

Tubulin protein is a well-validated cancer drug target

ThromboGenics receives IWT grant to study potential new biotherapeutics for DME

Metallic toys, low-cost jewelry can affect children's health

New study shows male hormones play important role; may enhance IVF therapy in women

Plymouth University enters partnership with Brain Tumour Research

Researchers develop silk-based surgical plates and screws to repair bone fractures

Plymouth becomes active research partner with Brain Tumour Research

Bruker opens new preclinical imaging center of excellence for the Americas

Procellera technology enhances cell migration in in-vitro laboratory testing

A-PARADDISE consortium obtains funds to develop innovative therapies for neglected parasitic diseases

Mindray's net revenues increase 16.5% to $368.4 million in fourth quarter 2013

Hypervirulent S. pneumoniae mutants discovered

New methodology for rapid detection of antibiotics in blood paves way to drug development, personalized treatment

H4 receptor activation plays part in NSCLC progression

Researchers identify novel strategies to develop more efficient vaccines against encapsulated bacteria

Scientists propose improved method of screening salmonella vaccines in small animal studies

Researchers present new drug candidate that selectively kills cancer cells through starvation

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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