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Key regulator of lens development also controls mechanosensory neuron development

A gene known to control lens development in mice and humans is also crucial for the development of neurons responsible for mechanosensory function, as neurobiologists of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch have now discovered.

22 Feb 2012

Fructose may not be to blame for obesity

Is fructose being unfairly blamed for the obesity epidemic? Or do we just eat and drink too many calories? Researchers from St. Michael's Hospital reviewed more than 40 published studies on whether the fructose molecule itself causes weight gain.

22 Feb 2012

Telomeres - the indicators of aging - are highly susceptible to stress and depression

Stress has numerous detrimental effects on the human body. Many of these effects are acutely felt by the sufferer, but many more go 'unseen', one of which is shortening of telomere length.

22 Feb 2012

Combination of gemcitabine and MRK003 kills pancreatic cancer cells

Cancer Research UK scientists have revealed how a combination of two very different drugs - currently being tested in clinical trials - amplifies the destruction of pancreatic cancer cells, according to research published in the Journal of Experimental Medicine, today.

22 Feb 2012

Cedars-Sinai scientist to study potential treatments for AD

A Cedars-Sinai research scientist has been awarded two national grants totaling more than $2.5 million, including a prestigious Research Project Grant from the National Institutes of Health to study potential treatments for Alzheimer's disease.

21 Feb 2012

University of Pennsylvania, IMUC enter license agreement for dendritic-cell production method

ImmunoCellular Therapeutics today announced that it has entered into an agreement with the University of Pennsylvania under which University of Pennsylvania has granted the Company an exclusive, worldwide license for a patent pending technology for the production of high-activity dendritic cells.

21 Feb 2012

FDA grants orphan-drug designation to Arno's AR-42 for treatment of meningioma, schwannoma

Arno Therapeutics, Inc. announced today that its investigational compound, AR-42, has been granted orphan-drug designation by the U.S. Food and Drug Administration for the treatment of meningioma and schwannoma of the central nervous system.

21 Feb 2012

Xencor, Boehringer Ingelheim partner to develop and supply biosuperior monoclonal antibodies

Xencor, Inc., a company using its proprietary Protein Design Automation (PDA) platform technology to engineer next-generation antibodies, and Boehringer Ingelheim announced today a collaboration agreement for certain Xencor biosuperior monoclonal antibodies.

21 Feb 2012

Biotech company defends patent on gene mutation for breast cancer

A US biotechnology company is defending the granting of a controversial patent over a common genetic mutation for breast cancer, rejecting accusations it amounts to the privatization of the human body.

21 Feb 2012

GTx fourth quarter net loss increases to $10.7 million

GTx, Inc. today provided a Company update and reported financial results for the fourth quarter and full year 2011.

21 Feb 2012

Genomic instability allows malignant cells to acquire more deadly characteristics

Genomic instability caused by an erosion of the protective caps on chromosomes, followed by activation of an enzyme that reinforces those aps, allows malignant cells to evade destruction and acquire more deadly characteristics, researchers report in an Online Now article at the journal Cell.

21 Feb 2012

Telomerase reactivation in malignant cells after genomic instability causes cancer progression

Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive and spread, scientists report in the Feb. 17 issue of Cell.

21 Feb 2012

Overall 'health' of 152 countries around the world

A growing world population, mixed with the threat of climate change and mounting financial problems, has prompted University of British Columbia researchers to measure the overall 'health' of 152 countries around the world.

21 Feb 2012

Gene that destroys cancerous cells also causes ageing

The role of one of our genes which protects us from cancer but could also cause us to age will be explained in a lecture at the University of Leicester.

21 Feb 2012

DNA ‘nanorobot’ effectively targets cancer leaving healthy cells untouched: Study

Researchers have developed ‘nano-sized’ probes built from DNA that can seek and destroy cancer cells, leaving healthy cells untouched. These ‘nanorobots’ release their drug payload only when they reach and identify their target and are believed to improve many treatments for disease.

20 Feb 2012

Natural compound of Chilean avocado plant can combat resistant yellow staphylococci

Aggressive infections in hospitals are an increasing health problem worldwide. The development of bacterial resistance is alarming. Now a young Danish scientist has found a natural substance in a Chilean rainforest plant that effectively supports the effect of traditional treatment with antibiotics.

20 Feb 2012

EC approves Plexxikon's Zelboraf to treat BRAF mutation-positive MM

Plexxikon Inc., a member of Daiichi Sankyo Group, today announced that the European Commission has approved Zelboraf (vemurafenib) for the monotherapy treatment of adult patients with BRAFV600 mutation-positive unresectable or metastatic melanoma.

20 Feb 2012

Researchers track structural changes during formation of new memories

New connections between brain cells emerge in clusters in the brain as animals learn to perform a new task, according to a study published in Nature on February 19 (advance online publication). Led by researchers at the University of California, Santa Cruz, the study reveals details of how brain circuits are rewired during the formation of new motor memories.

20 Feb 2012

Smoke forecasting tools can help protect individuals and public health professionals

Satellite images, air quality measurements and smoke forecasting models are useful tools to help individuals and public health professionals prepare for smoke episodes in areas at risk from forest fire smoke, according to University of British Columbia researcher Michael Brauer.

20 Feb 2012

Study reveals potential strength of different anti-HIV combination drugs

Using a mathematical formula that carefully measures the degree to which HIV infection of immune system cells is stalled by antiretroviral therapy, AIDS experts at Johns Hopkins have calculated precisely how well dozens of such anti-HIV drugs work, alone or in any of 857 likely combinations, in suppressing the virus. Results of the team's latest research reveal how some combinations work better than others at impeding viral replication, and keeping the disease in check.

19 Feb 2012

Cell News and Research

Key regulator of lens development also controls mechanosensory neuron development

Fructose may not be to blame for obesity

Telomeres - the indicators of aging - are highly susceptible to stress and depression

Combination of gemcitabine and MRK003 kills pancreatic cancer cells

Cedars-Sinai scientist to study potential treatments for AD

University of Pennsylvania, IMUC enter license agreement for dendritic-cell production method

FDA grants orphan-drug designation to Arno's AR-42 for treatment of meningioma, schwannoma

Xencor, Boehringer Ingelheim partner to develop and supply biosuperior monoclonal antibodies

Biotech company defends patent on gene mutation for breast cancer

GTx fourth quarter net loss increases to $10.7 million

Genomic instability allows malignant cells to acquire more deadly characteristics

Telomerase reactivation in malignant cells after genomic instability causes cancer progression

Overall 'health' of 152 countries around the world

Gene that destroys cancerous cells also causes ageing

DNA ‘nanorobot’ effectively targets cancer leaving healthy cells untouched: Study

Natural compound of Chilean avocado plant can combat resistant yellow staphylococci

EC approves Plexxikon's Zelboraf to treat BRAF mutation-positive MM

Researchers track structural changes during formation of new memories

Smoke forecasting tools can help protect individuals and public health professionals

Study reveals potential strength of different anti-HIV combination drugs

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