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Researchers discover new gene linked to MLCRD

Researchers have found a new gene that, when mutated, can lead to lymphoedema (swollen limbs) as part of a rare disorder that can also cause problems with eye and brain development. This is the fourth lymphoedema-related gene found by the same researchers in three years, and the first linked to the eyes and brain. They say it could lead to better diagnosis and treatment for lymphoedema, an area that has been poorly understood previously.

27 Jan 2012

Rotational motion plays a critical role in ability of breast cells to form acini

In a study that holds major implications for breast cancer research as well as basic cell biology, scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory have discovered a rotational motion that plays a critical role in the ability of breast cells to form the spherical structures in the mammary gland known as acini.

27 Jan 2012

Renowned publisher introduces Cell Reports

Cell Press reinforces its commitment to provide a broad range of publishing options for the life sciences community with the inaugural issue of a new open-access journal: Cell Reports.

27 Jan 2012

Scientists connect two signature characteristics of pancreatic cancer

Scientists have connected two signature characteristics of pancreatic cancer, identifying a self-perpetuating "vicious cycle" of molecular activity and a new potential target for drugs to treat one of the most lehal forms of cancer.

27 Jan 2012

Strong link between high HuR protein levels and malignancy of HCC

Researchers at CIC Biogune, the Cooperative Centre for Research into Biosciences and led by Dr. Maria Luz Martinez Chantar, have found a strong relationship between high levels of Hu antigen R (HuR) protein and the malignancy of Hepatocellular Carcinoma, through a novel molecular process in the investigation of this pathology and known as neddylation.

27 Jan 2012

Weill Cornell establishes Office of Faculty Development

Weill Cornell Medical College has announced the establishment of the Office of Faculty Development dedicated to assisting its physicians, researchers and educators in achieving academic success at each stage of their careers, with targeted activities that focus on the needs of junior, mid-career and senior faculty.

27 Jan 2012

New links between leukemia cells and osteoblasts

University of Rochester Medical Center researchers have discovered new links between leukemia cells and cells involved in bone formation, offering a fresh perspective on how the blood cancer progresses and raising the possibility that therapies for bone disorders could help in the treatment of leukemia.

27 Jan 2012

Amgen enters definitive merger agreement to acquire Micromet

Amgen and Micromet, Inc. today announced that the companies have entered into a definitive merger agreement under which Amgen will acquire Micromet, a biotechnology company founded in Germany with its research and development (R&D) center in Munich and headquarters in Rockville, Md., for $11 per share in cash.

27 Jan 2012

New technique to overcome genetic oddity of P. falciparum

The parasite that causes malaria is a genetic outlier, which has prevented scientists from discovering the functions of most of its genes. Researchers at National Jewish Health and Yale University School of Medicine have devised a technique to overcome the genetic oddity of Plasmodium falciparum, the major cause of human malaria.

27 Jan 2012

Routine PET/CT scan use in head and neck cancer patients can detect local recurrences

Routine use of positron emission tomography/computed tomography (PET/CT) scans in head and neck cancer patient follow-up can detect local recurrences before they become clinically apparent and may improve the outcome of subsequent salvage therapy, according to a study presented at the Multidisciplinary Head and Neck Cancer Symposium, sponsored by AHNS, ASCO, ASTRO and SNM.

27 Jan 2012

Boehringer Ingelheim initiates two afatinib phase III trials in head and neck cancer

Boehringer Ingelheim announced today the initiation of two phase III clinical trials, LUX-Head & Neck 1 and LUX-Head & Neck 2. These trials evaluate afatinib in patients with metastatic and recurrent head and neck cancer, and in patients with locally advanced disease, respectively.

27 Jan 2012

LEO Pharma receives FDA approval for Picato topical gel to treat AK

LEO Pharma announced today that the U.S. Food and Drug Administration (FDA) approved Picato (ingenol mebutate) gel (0.015%, 0.05%) for the topical treatment of actinic keratosis.

27 Jan 2012

Celgene signs definitive merger agreement to acquire Avila

Celgene Corporation and Avila Therapeutics, Inc., a privately held biotechnology company developing targeted covalent drugs that treat diseases through protein silencing, today announced a definitive merger agreement under which Celgene Corporation will acquire Avila Therapeutics, Inc.

26 Jan 2012

Breakthroughs in Alzheimer’s disease research

Researchers are closer to understanding Alzheimer’s disease using a new stem cell technique. They have successfully replicated Alzheimer’s disease neurons with stem cells for the first time.

26 Jan 2012

Amorcyte commences enrollment in PreSERVE Phase 2 trial for acute myocardial infarction

Amorcyte, LLC, a NeoStem, Inc. company today announces the enrollment of the first patient in the Amorcyte PreSERVE Phase 2 trial for acute myocardial infarction.

25 Jan 2012

Oramed receives Australian patent for core technology in oral delivery of peptides

Marking a major milestone for the Company, Oramed Pharmaceuticals Inc., a developer of oral drug delivery systems, announced today that it has received approval for a key patent by the Australian Patent Office.

25 Jan 2012

Scientists evaluate growth, differentiation and function of iPSC-derived NPCs in PD

Induced pluripotent stem cells (iPSC) are a promising avenue for cell replacement therapy in neurologic diseases. For example, mouse and human iPSCs have been used to generate dopaminergic (DA) neurons that improve symptoms in rat Parkinson's disease models. Reporting in the current issue of the Journal of Parkinson's Disease, a group of scientists from Japan evaluated the growth, differentiation, and function of human-derived iPSC-derived neural progenitor cells (NPCs) in a primate model, elucidating their therapeutic potential.

25 Jan 2012

BioTime obtains license from Wistar Institute for technology related to SP100 gene

BioTime, Inc. today announced that it has obtained an exclusive license from The Wistar Institute in Philadelphia, PA for technology related to a gene designated as SP100.

25 Jan 2012

Seattle Children's receives $5M gift from Ben Towne for pediatric cancer study

Seattle Children's Research Institute today announced a $5 million gift from Ben Towne Pediatric Cancer Research Foundation. The funding will be used to accelerate the work of Michael Jensen, MD, and his Seattle Children's Research Institute team who are creating new cancer treatments that reprogram a child's immune system to attack and kill cancer cells with the goal of minimizing or even eliminating the need for chemotherapy or radiation.

25 Jan 2012

HHMI honors EMBL Monterotondo researcher with International Early Career Scientist award

Rocio Sotillo, a staff scientist at the European Molecular Biology Laboratory (EMBL) in Monterotondo, is one of 28 outstanding young biomedical scientists who have been honoured with a Howard Hughes Medical Institute (HHMI) International Early Career Scientist award this year.

25 Jan 2012

Cell News and Research

Researchers discover new gene linked to MLCRD

Rotational motion plays a critical role in ability of breast cells to form acini

Renowned publisher introduces Cell Reports

Scientists connect two signature characteristics of pancreatic cancer

Strong link between high HuR protein levels and malignancy of HCC

Weill Cornell establishes Office of Faculty Development

New links between leukemia cells and osteoblasts

Amgen enters definitive merger agreement to acquire Micromet

New technique to overcome genetic oddity of P. falciparum

Routine PET/CT scan use in head and neck cancer patients can detect local recurrences

Boehringer Ingelheim initiates two afatinib phase III trials in head and neck cancer

LEO Pharma receives FDA approval for Picato topical gel to treat AK

Celgene signs definitive merger agreement to acquire Avila

Breakthroughs in Alzheimer’s disease research

Amorcyte commences enrollment in PreSERVE Phase 2 trial for acute myocardial infarction

Oramed receives Australian patent for core technology in oral delivery of peptides

Scientists evaluate growth, differentiation and function of iPSC-derived NPCs in PD

BioTime obtains license from Wistar Institute for technology related to SP100 gene

Seattle Children's receives $5M gift from Ben Towne for pediatric cancer study

HHMI honors EMBL Monterotondo researcher with International Early Career Scientist award

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