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Breakthrough obesity treatments on the horizon, rivaling surgery's success

New obesity pharmacotherapies, including GLP-1 receptor agonists and combinations of entero-pancreatic hormones, show promise in achieving significant weight loss, potentially rivaling bariatric surgery's effectiveness.

4 Feb 2024

Lentils lower cholesterol and sugar response, study finds

Twelve weeks of daily lentil consumption significantly improves fasting cholesterol, postprandial glucose, and inflammation in overweight adults, offering a dietary strategy to enhance metabolic health without gastrointestinal distress.

4 Feb 2024

Small-molecule A485 mobilizes white blood cells on demand

New study reveals a small molecule that can selectively mobilize white blood cells, offering potential treatments for diseases with abnormal leukocyte counts.

3 Feb 2024

Has a decade of maternal pertussis vaccination reduced its effectiveness?

Research indicates maternal immunization against pertussis remains crucial for newborn protection despite concerns of reduced vaccine effectiveness over time, underscoring its vital role in preventing infant mortality.

3 Feb 2024

CAR T cells target senescent cells, improve healthspan in mice

Chimeric antigen receptor (CAR) T cells have transformed the treatment of blood cancers in recent years. And there have been positive signs the "living drugs" can be harnessed against other diseases, like autoimmune disorders.

2 Feb 2024

Study shows how low dose of cadmium produces deleterious stress in lung epithelial cells

Cigarette smoke exposure is associated with the development and severity of chronic obstructive pulmonary disease, or COPD, which is the third leading cause of death worldwide.

2 Feb 2024

NAEC develops updated guidelines to improve quality of care for people with severe epilepsy

The National Association of Epilepsy Centers (NAEC) has developed updated guidelines that outline the comprehensive services and resources epilepsy centers should provide to improve quality of care for people whose epilepsy is not well-controlled.

2 Feb 2024

Study links social inequality to lower pain relief during labor

In a study of women in labor in the U. S., social inequity was associated with lower use of neuraxial analgesia -- an epidural or spinal pain reliever-- among non-Hispanic White women and, to a greater extent, among African American women, according to research at Columbia University Mailman School of Public Health and Columbia Vagelos College of Physicians and Surgeons (P&S).

2 Feb 2024

New trial explores cold-pressed castor oil as safe, natural treatment for dry-eye disease

Researchers at the University of Auckland are running a trial of castor oil as a potential safe and natural treatment for dry-eye disease following a successful pilot study.

2 Feb 2024

Possibility of wildlife-to-human crossover heightens concern about chronic wasting disease

Each fall, millions of hunters across North America make their way into forests and grasslands to kill deer. Over the winter, people chow down on the venison steaks, sausage, and burgers made from the animals.

2 Feb 2024

Study says parents may overshoot fluoride toothpaste dose for toddlers, risking dental fluorosis

Study finds parents significantly overdose children with fluoride toothpaste, suggesting a shift to fluoride-free alternatives to prevent overconsumption and potential fluorosis.

1 Feb 2024

Long COVID and ME/CFS share isimilarities in immune system dysfunction, study finds

A study led by UMass Chan Medical School viral immunologists Liisa Selin, MD, PhD, and Anna Gil, PhD, discovered similarities in immune system dysfunction as a potential biomarker among people living with long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

1 Feb 2024

IU surgeon-scientist investigates the role of sinus microbiome in chronic rhinosinusitis

An Indiana University School of Medicine surgeon-scientist is leading a multi-institutional grant investigating the role of the sinus microbiome in chronic rhinosinusitis, an inflammatory disease that causes the lining of the sinuses to swell.

1 Feb 2024

Next-gen BTK degrader could help overcome treatment resistance in chronic lymphocytic leukemia

New research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations has identified a next-generation BTK degrader that could help overcome treatment resistance in chronic lymphocytic leukemia (CLL) and related blood cancers.

1 Feb 2024

Nerve stimulation plus physical rehabilitation may boost recovery of arm and hand function

Combining brain stimulation with intense physical rehabilitation helped stroke survivors recover movement in their arms and hands and maintain these improvements for one year, according to a study to be presented at the American Stroke Association's International Stroke Conference 2024.

1 Feb 2024

Study observes rapid immune response in individuals switching to vegan and keto diets

Researchers evaluated the impact of vegan and ketogenic diets on immune response and gut microbiota in humans.

1 Feb 2024

Virtual relaxation therapy reduces distress in end-of-life care

A new study published in Frontiers in Virtual Reality explored the effectiveness of a psychological strategy called Flourishing-Life-Of-Wish Virtual Reality Therapy (FLOW-VRT)® in helping people cope with their symptoms and achieve relaxation at the end of life.

1 Feb 2024

Circulatory cholesterol levels are inversely linked to mortality of patients with sepsis and critical illness

The association between biomarkers of cholesterol homeostasis and mortality in critically ill patients.

1 Feb 2024

UH researcher aims to revolutionize treatment regimens for triple-negative breast cancer

A researcher at the University of Houston College of Pharmacy Drug Discovery Institute is working to revolutionize treatment regimens for triple-negative breast cancer (TNBC) by proving that nebivolol, an FDA-approved drug for high blood pressure, is effective in treating it.

31 Jan 2024

Age-related changes in the brain network may explain why older women feel more pain

A new study has found that the brain system enabling us to inhibit our own pain changes with age, and that gender-based differences in those changes may lead females to be more sensitive to moderate pain than males as older adults.

31 Jan 2024

Chronic News and Research

Breakthrough obesity treatments on the horizon, rivaling surgery's success

Lentils lower cholesterol and sugar response, study finds

Small-molecule A485 mobilizes white blood cells on demand

Has a decade of maternal pertussis vaccination reduced its effectiveness?

CAR T cells target senescent cells, improve healthspan in mice

Study shows how low dose of cadmium produces deleterious stress in lung epithelial cells

NAEC develops updated guidelines to improve quality of care for people with severe epilepsy

Study links social inequality to lower pain relief during labor

New trial explores cold-pressed castor oil as safe, natural treatment for dry-eye disease

Possibility of wildlife-to-human crossover heightens concern about chronic wasting disease

Study says parents may overshoot fluoride toothpaste dose for toddlers, risking dental fluorosis

Long COVID and ME/CFS share isimilarities in immune system dysfunction, study finds

IU surgeon-scientist investigates the role of sinus microbiome in chronic rhinosinusitis

Next-gen BTK degrader could help overcome treatment resistance in chronic lymphocytic leukemia

Nerve stimulation plus physical rehabilitation may boost recovery of arm and hand function

Study observes rapid immune response in individuals switching to vegan and keto diets

Virtual relaxation therapy reduces distress in end-of-life care

Circulatory cholesterol levels are inversely linked to mortality of patients with sepsis and critical illness

UH researcher aims to revolutionize treatment regimens for triple-negative breast cancer

Age-related changes in the brain network may explain why older women feel more pain

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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