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Novel CRISPR-based technology for rapidly screening genes to understand human health and disease

Zebrafish- small, fast-growing creatures who share many of the same genes as humans- are instrumental to many biologists, who find them uniquely well suited for studying a wide range of questions, from how organisms develop to how the nervous system drives behavior.

20 Aug 2021

Bristol scientists show how laboratory evolution can give rise to highly efficient enzymes

Researchers at the University of Bristol have shown how laboratory evolution can give rise to highly efficient enzymes for new-to-nature reactions, opening the door for novel and more environmentally friendly ways to make drugs and other chemicals.

20 Aug 2021

Chemical Insights, Underwriters Laboratories and GSU launch research initiative on vaping and e-cigarettes

Chemical Insights Research Institute, Underwriters Laboratories Inc., and Georgia State University's School of Public Health announced the launch of a research initiative on understanding human exposure and the potential health effects of vaping and e-cigarettes.

20 Aug 2021

Npas4 gene may be a master timekeeper for the brain's circadian clock

A gene called Npas4, already known to play a key role in balancing excitatory and inhibitory inputs in brain cells, appears to also be a master timekeeper for the brain's circadian clock, new research led by UT Southwestern scientists suggests.

20 Aug 2021

Scientists develop nature-inspired steerable catheter for brain surgery

A team of engineers and physicians has developed a steerable catheter that for the first time will give neurosurgeons the ability to steer the device in any direction they want while navigating the brain's arteries and blood vessels.

19 Aug 2021

Research could enable clinicians to produce patient-matched cells for treating muscle-related diseases

Investigators who previously developed a recipe for turning skin cells into primitive muscle-like cells that can be maintained indefinitely in the lab without losing the potential to become mature muscle have now uncovered how this recipe works and what molecular changes it triggers within cells.

19 Aug 2021

NCCN joins the growing call for mandatory COVID-19 vaccination for healthcare workers

The National Comprehensive Cancer Network- a nonprofit alliance of leading cancer centers across the United States- joins the growing call for mandatory COVID-19 vaccination for all eligible healthcare workers.

19 Aug 2021

Long-term circadian rhythm disruption induces Alzheimer's-like pathology in rats

Disrupted circadian rhythms, which can even be caused by chronic light exposure, affects normal physiological functions, resulting in anxiety, hyperactivity, and memory deficits.

19 Aug 2021

249,000 UK-donated AstraZeneca COVID-19 vaccines reach Ghana

A shipment of 249,000 UK-donated AstraZeneca COVID-19 vaccines has today (Wednesday, 18 August) arrived in Accra’s Kotoka International Airport.

19 Aug 2021

Genetic nurture has a significant effect on child's educational success, study finds

A child's educational success depends on the genes that they haven't inherited from their parents, as well as the genes they have, according to a new study led by UCL researchers.

19 Aug 2021

Prior treatment may impact efficacy of ACT-TIL in patients with metastatic melanoma

Patients with metastatic melanoma that had relapsed on anti-PD-1 therapies or BRAF/MEK inhibitors did not respond as well to an investigational therapy that involves the adoptive cell transfer of tumor-infiltrating lymphocytes (ACT-TIL) as patients naïve to these treatments.

19 Aug 2021

HMGA1 plays role in gastric cancer cell proliferation and metastasis

Aging-US published "HMGA1 promotes gastric cancer growth and metastasis by transactivating SUZ12 and CCDC43 expression" which reported that HMGA1 is overexpressed in GC cells and the high expression of HMGA1 was correlated with worse survival in GC patients using a bioinformatics assay.

19 Aug 2021

Researchers discover glycan 'gates' that open to allow SARS-CoV-2 entry

Since the early days of the COVID pandemic, scientists have aggressively pursued the secrets of the mechanisms that allow severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to enter and infect healthy human cells.

19 Aug 2021

Scientists develop a new way to deliver molecular therapies to cells

Researchers from MIT, the McGovern Institute for Brain Research at MIT, the Howard Hughes Medical Institute, and the Broad Institute of MIT and Harvard have developed a new way to deliver molecular therapies to cells.

19 Aug 2021

Cognitive rehabilitation found to be effective in treating multiple sclerosis-related cognitive dysfunction

In a review of recent literature, a team of researchers from Kessler Foundation conclude that cognitive rehabilitation programs are efficacious in treating multiple sclerosis-related cognitive dysfunction, and urge clinicians to consider this low-cost, low-risk, yet effective treatment approach for their patients.

19 Aug 2021

Study reveals mechanism behind male infertility caused by autoimmune disease

Investigators have found that the absence of autoimmune regulator (Aire) in mice results in fertility problems similar to those affecting men with autoimmune polyendocrine syndrome type I (APS-1).

19 Aug 2021

Research project identifies deficiencies in models used for assessing chemical safety at workplaces

A research project affiliated with the University of Helsinki's Institute for Atmospheric and Earth System Research has identified serious deficiencies in the Stoffenmanager and Advanced REACH Tool occupational exposure models used for assessing chemical safety and calls for the discontinuation of their use in statutory chemical safety assessment.

19 Aug 2021

Vaccines remain the most effective way to protect against COVID-19 Delta variant, study says

Obtaining two vaccine doses remains the most effective way to ensure protection against the COVID-19 Delta variant of concern dominant in the UK today, according to a study from the University of Oxford.

19 Aug 2021

Research uses mathematical modeling to find an equitable way for sharing vaccines between nations

New research from the University of Oxford and the UK Centre for Ecology & Hydrology, published today in Frontiers in Public Health, uses mathematical modeling to determine the most equitable way to share vaccines between nations.

19 Aug 2021

Study identifies the cause and treatment for rare rheumatoid-like autoinflammatory condition

The absence of a protein that activates the body's antiviral defenses can cause a rare rheumatoid-like autoinflammatory condition that is treatable with an FDA-approved class of drugs known as TNF (tumor necrosis factor) inhibitors, a global research team led by Mount Sinai has found.

19 Aug 2021

Research News and Research

Novel CRISPR-based technology for rapidly screening genes to understand human health and disease

Bristol scientists show how laboratory evolution can give rise to highly efficient enzymes

Chemical Insights, Underwriters Laboratories and GSU launch research initiative on vaping and e-cigarettes

Npas4 gene may be a master timekeeper for the brain's circadian clock

Scientists develop nature-inspired steerable catheter for brain surgery

Research could enable clinicians to produce patient-matched cells for treating muscle-related diseases

NCCN joins the growing call for mandatory COVID-19 vaccination for healthcare workers

Long-term circadian rhythm disruption induces Alzheimer's-like pathology in rats

249,000 UK-donated AstraZeneca COVID-19 vaccines reach Ghana

Genetic nurture has a significant effect on child's educational success, study finds

Prior treatment may impact efficacy of ACT-TIL in patients with metastatic melanoma

HMGA1 plays role in gastric cancer cell proliferation and metastasis

Researchers discover glycan 'gates' that open to allow SARS-CoV-2 entry

Scientists develop a new way to deliver molecular therapies to cells

Cognitive rehabilitation found to be effective in treating multiple sclerosis-related cognitive dysfunction

Study reveals mechanism behind male infertility caused by autoimmune disease

Research project identifies deficiencies in models used for assessing chemical safety at workplaces

Vaccines remain the most effective way to protect against COVID-19 Delta variant, study says

Research uses mathematical modeling to find an equitable way for sharing vaccines between nations

Study identifies the cause and treatment for rare rheumatoid-like autoinflammatory condition

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