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Prophylactic administration of SARS-CoV-2 specific immunoglobulin Y generated in chicken eggs displays protective effects in infected mice

A new study characterized and tested the antibody activity of SARS-CoV-2-specific immunoglobulin Y (IgY) derived from the eggs laid by chickens immunized with recombinant SARS-CoV-2 receptor binding domain (RBD) protein.

21 Sep 2022

What is the impact of COVID-19 treatments targeting intracellular Neu1?

In a new study, researchers assessed the impact of targeting intracellular Neu1 on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

14 Sep 2022

UB study reveals a mechanism of gene evolution generating mucin function

From the slime coating slugs to the saliva in our mouths, many slippery bodily fluids contain mucus. So how did this marvel of biology evolve?

26 Aug 2022

CD98 identified as a key mediator of pro-fibrotic and acute inflammatory responses in the lung

Researchers investigated the role of the CD98 glycoprotein in inducing an inflammatory response to SARS-CoV-2 in patients of progressive fibrosis interstitial lung diseases, including the archetypal PFILD, idiopathic pulmonary fibrosis.

18 Aug 2022

Men exposed to industrial air pollution exhibit sperm mitochondrial DNA deletions

Researchers compare the length spectra of sperm mitochondrial DNA deletions in two seasons with varied air pollution levels.

14 Aug 2022

Assessing immunization capacity of vaccine platforms with DNA origami harboring SARS-CoV-2 receptor binding domain

Researchers demonstrated that vaccine frameworks containing deoxyribonucleic acid (DNA) origami possessing SARS-CoV-2 receptor-binding domain induce strong protective immunity.

8 Aug 2022

DNA may act as nutritional source for E. coli

Findings of a new experiment could be helpful in understanding how DNA acts as a nutrient for gut bacteria, and its impact on the health of the host.

18 Jul 2022

Asymptomatic monkeypox infection detected from routine sexual health samples

A new study reports on the incidence of subclinical monkeypox infection among individuals attending a sexual health clinic in Belgium.

7 Jul 2022

The pineapple-derived jacalin-related lectin as a potential anti-SARS-CoV-2 agent

Scientists demonstrated that the pineapple-derived jacalin-related lectin (AcmJRL/AnLec) could be an anti-SARS-CoV-2 agent.

31 May 2022

Neutralization of SARS-CoV-2 by plant-made neutralizing monoclonal antibodies

In a recent study published in the journal Vaccines, researchers developed plant-based monoclonal antibodies (mAbs) against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

17 May 2022

An Ad5 vectored COVID vaccine expressing an S1-N fusion protein

In a recent study posted to the bioRxiv* preprint server, researchers characterized the development of multiple adenovirus-vectored and subunit recombinant protein severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidates.

12 May 2022

CRISPR/Cas9 deletions induce adverse on-target genomic effects

Researchers utilized a CRISPR/Cas9 system to evaluate the usage of tRNA by deleting two tRNA genes from the genomes of hyper hepatocellular carcinoma and human near-haploid chronic myeloid leukemia cells.

27 Apr 2022

The diversity of transcriptional targets between four different coronavirus nsp1 proteins

Researchers investigated variations in the host immune response-elicited by non-structural protein 1 of coronaviruses.

22 Apr 2022

SARS-CoV-2 detected using smartphone biosensor

Researchers describe the use of RT-LAMP in combination with particle diffusometry to detect SARS-CoV2 in saliva samples.

7 Apr 2022

Researchers characterize vaccines for infectious bronchitis virus

A new study characterized the genetic and immunological aspects of the infectious bronchitis virus (IBV) vaccines commercially used in Korea.

25 Mar 2022

Exploring the oligomerizing behavior of SARS-CoV-2 accessory protein 7b

Researchers tested the hypothesis that severe SARS-CoV-2 accessory protein 7b forms oligomers with ion channel activity in lipid and detergent environments.

23 Mar 2022

Novel fusion inhibitor blocks SARS-CoV-2 spike-mediated cell-cell fusion

Researchers constructed a novel fusion inhibitor−based recombinant protein, referred to as 5−Helix, to block SARS-CoV-2 spike-mediated cell-cell fusion.

17 Mar 2022

SARS-CoV-2 protein interactions with viral and host RNAs in authentic virus-infected cells

Researchers investigated protein interactions of SARS-CoV-2 with host and viral RNAs in infected cells.

1 Mar 2022

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Researchers evaluated the pathogenicity and replication potential of SARS-CoV-2 VOC Omicron lineage, BA.2 in immunocompetent mice and hamsters.

28 Feb 2022

New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings

A recent study shows how a novel and integrated lab-on-a-chip platform can represent a rapid, affordable, and exact molecular diagnostic tool for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The paper is currently available for free on the medRxiv* preprint server while it undergoes peer review.

9 Jan 2022