Neurosurgery News and Research

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Concern over two cases of monkeypox-related neurological complications in the U.S.

A new study published in the CDC's Morbidity and Mortality Weekly Report analyzed two people with encephalomyelitis associated with monkeypox disease in Colorado and DC during the current outbreak.

15 Sep 2022

Winners of the 2022 CURE-19 Research Pilot Grants announced

The Arnhold Institute for Global Health at the Icahn School of Medicine at Mount Sinai and NYC Health + Hospitals have announced the 2022 awardees of the CURE-19 Research Pilot Grants, an initiative to support collaborative, interdisciplinary COVID-19 research that will address both the pandemic and root causes of health disparities in New York City.

14 Sep 2022

Research could lead to a new therapeutic option for patients with bladder cancer

Mount Sinai researchers have made two important discoveries about the mechanism by which bladder cancer cells foil attacks from the immune system.

12 Sep 2022

Low-dose ketamine is safe and effective to treat children with ADNP syndrome, study suggests

Results of a small, but unique research study, led by researchers from the Seaver Autism Center for Research and Treatment at Mount Sinai and published online in Human Genetics and Genomic Advances, suggest that low-dose ketamine is generally safe, well-tolerated and effective to treat clinical symptoms in children diagnosed with ADNP syndrome (also known as Helsmoortel-VanDerAa syndrome), a rare neurodevelopmental disorder caused by mutations in the activity dependent neuroprotective protein (ADNP) gene.

6 Sep 2022

Combined stem cell and gene therapy shows promise to treat patients with ALS

Cedars-Sinai investigators have developed an investigational therapy using support cells and a protective protein that can be delivered past the blood-brain barrier.

5 Sep 2022

Study shows encouraging therapeutic options for patients with relapsed multiple myeloma

Mount Sinai researchers have published results that show encouraging therapeutic options for patients with the blood cancer multiple myeloma after first-line treatment with bispecific antibodies fails.

1 Sep 2022

Implanted brain-stimulating device disrupts craving-related signals and reduces bingeing episodes

A small device that detects food craving-related brain activity in a key brain region, and responds by electrically stimulating that region, has shown promise in a pilot clinical trial in two patients with loss-of-control binge eating disorder (BED), according to researchers at the Perelman School of Medicine at the University of Pennsylvania.

29 Aug 2022

New risk assessment tool predicts mortality for atrial fibrillation patients after completion of TAVR

A large-scale international study led by Mount Sinai has yielded the first risk score that can help predict mortality for patients with atrial fibrillation (AFib) who have undergone a successful transcatheter aortic valve replacement (TAVR) and discharged home.

29 Aug 2022

Penn State receives $1.6 million grant to study the link between COVID-19 and cognitive decline

As populations around the globe age, dementia - often caused by Alzheimer's disease and related disorders - is a growing health issue for older adults worldwide.

26 Aug 2022

Three-drug medication effective in preventing recurrent cardiovascular events after a heart attack

A three-drug medication known as a "polypill," developed by the Spanish National Center for Cardiovascular Research (CNIC) and Ferrer, is effective in preventing secondary adverse cardiovascular events in people who have previously had a heart attack, reducing cardiovascular mortality by 33 percent in this patient population.

26 Aug 2022

Scientists demonstrate safety of neurosurgical procedure used to measure dopamine and serotonin

Scientists at Wake Forest University School of Medicine have demonstrated that a neurosurgical procedure used to research and measure dopamine and serotonin in the human brain is safe.

24 Aug 2022

New wireless sock monitoring system reduces fall rates among hospitalized patients

Research led by nurses at The Ohio State University Wexner Medical Center found that a new wireless sock monitoring system reduced fall rates among "fall-risk" patients hospitalized at Ohio State's Brain and Spine Hospital.

23 Aug 2022

Day-of-injury blood tests predict which TBI patients are likely to die or survive with severe disability

A study finds that blood tests taken the day of a traumatic brain injury can predict which patients are likely to die or survive with severe disability, allowing clinicians to make decisions earlier on possible treatment of TBI.

19 Aug 2022

Study reveals a strong potential therapy for treatment-resistant depression

Deep brain stimulation (DBS) to the superolateral branch of the medial forebrain bundle (MFB), which is linked to reward and motivation, revealed metabolic brain changes over 12 months post-DBS implantation, making it a strong potential therapy for treatment-resistant depression according to researchers at UTHealth Houston.

19 Aug 2022

Hackensack Meridian Health becomes second in the world to implant Impella Bridge-to-Recovery heart pump

Hackensack Meridian Health, Hackensack University Medical Center cardiac surgeon Yuriy Dudiy, M.D. became the second in the world to successfully implant the Impella Bridge-to-Recovery (BTR)™ heart pump for the technology's U.S. Food and Drug Administration (FDA) early feasibility study (EFS) investigational device exemption (IDE).

17 Aug 2022

Mount Sinai and Regeneron Genetics Center launch a new human genome sequencing research project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022

Novel model reveals how genomic instability arises in histologically benign tissue

Understanding which cells give rise to which areas of cancer can improve our understanding of how a tumor has grown and developed, including how it has changed genetically, over time. This has been made possible using a new technique called spatial transcriptomics, which allows scientists to see what genetic changes take place without breaking up the tissue they're looking at.

11 Aug 2022

Study quantifies the prognostic accuracy of two protein biomarkers

Blood tests taken within 24 hours of a traumatic brain injury (TBI) flag which patients are likely to die and which patients are likely to survive with severe disability, according to a study headed by UC San Francisco, the University of Pennsylvania and the University of Michigan. Their results -- available within minutes -- may confirm the need for prompt surgical interventions or may help guide conversations with families in cases of devastating injury.

11 Aug 2022

Novel class of drug regresses active brain metastases in breast cancer patients

An Austrian study led by MedUni Vienna showed that active brain metastases in breast cancer patients are partially or even completely regressed by a novel class of drug. This is a chemical conjugate of an antibody and a chemotherapy drug that, according to current findings, opens up a completely new avenue in oncological research and targeted therapy.

10 Aug 2022

Mount Sinai receives $500,000 SU2C grant to identify therapeutic combinations for KRAS-mutant lung cancers

Mount Sinai is leading a team of lung cancer researchers that has been awarded a three-year, $500,000 grant from Stand Up To Cancer to explore therapeutic approaches to lung tumors with mutations in the KRAS gene, an undertaking that could have a significant impact for a large population of cancer patients who currently lack effective treatment options.

9 Aug 2022