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PrimeraDx gets FDA clearance for ICEPlex C. difficile Assay Kit and ICEPlex System

PrimeraDx, a molecular diagnostics company, announced today that the ICEPlex C. difficile Assay Kit and the ICEPlex System have received 510(k) clearance from the United States Food and Drug Administration.

3 Dec 2013

Researchers offer promise of strategy for curing HIV infection

Researchers have used radioimmunotherapy (RIT) to destroy remaining human immunodeficiency virus (HIV)-infected cells in the blood samples of patients treated with antiretroviral therapy, offering the promise of a strategy for curing HIV infection. Results of the study were presented today at the annual meeting of the Radiological Society of North America (RSNA).

3 Dec 2013

New genetics promises to change faulty genes of future generations by using "designer sperm”

Bethesda, MD-Get ready: The "new genetics" promises to change faulty genes of future generations by introducing new, functioning genes using "designer sperm." A new research report appearing online in The FASEB Journal, shows that introducing new genetic material via a viral vector into the sperm of mice leads to the presence and activity of those genes in the resulting embryos.

3 Dec 2013

New finding links obesity and high-fat, high-sugar diets with changes in inflammatory status

Scientists have moved a step closer to an "obesity drug" that may block the effects of diets high in sugar and fats. In a new research report published in the December 2013 issue of The FASEB Journal, scientists show that there is an abnormal amount of an inflammatory protein called PAR2 in the abdominal fat tissue of overweight and obese humans and rats.

3 Dec 2013

EMD Serono's TocopheRx to focus on development of oral FSH agonists for infertility treatment

EMD Serono, Inc., a subsidiary of Merck KGaA, Darmstadt, Germany, announced today the creation of TocopheRx, a Boston-based spin-off company resulting from the Entrepreneur Partnership Program launched by Merck Serono, the biopharmaceutical division of Merck KGaA, Darmstadt, Germany, in April 2012.

3 Dec 2013

Cyclin D1 protein controls cell cycle progression, microRNA biogenesis in breast cancer

Cyclin D1, a protein that helps push a replicating cell through the cell cycle also mediates the processing and generation of mature microRNA, according to new research publishing November 29 in Nature Communications. The research suggests that a protein strongly implicated in human cancer also governs the non-protein-coding genome. The non-coding genome, previously referred to as junk DNA, makes up most of the human genome, and unlike the coding genome, varies greatly between species.

29 Nov 2013

Patrys to present data from PAT-SM6 Phase I/IIa trial in multiple myeloma at ASH conference

Patrys Limited (ASX: PAB), a clinical stage biotechnology company has announced that updated results from its PAT-SM6 Phase I/IIa clinical trial in multiple myeloma will be presented at the 55th American Society of Hematology Annual Meeting in New Orleans, LA on 7- 10 December 2013.

29 Nov 2013

Data from Patrys' PAT-SM6 Phase I/IIa trial in multiple myeloma to be presented at ASH Annual Meeting

Patrys Limited, a clinical stage biotechnology company has announced that updated results from its PAT-SM6 Phase I/IIa clinical trial in multiple myeloma will be presented at the 55th American Society of Hematology Annual Meeting in New Orleans, LA on 7- 10 December 2013.

29 Nov 2013

Certain Chinese medicines can regulate neurotrophic and apoptosis-related factors

Parkinson's disease is a common neurodegenerative disease in the elderly, which is pathologically characterized by selective loss of dopaminergic neurons. Compound preparations of Chinese medicines that can tonify the kidney have been reported to significantly improve symptoms of Parkinson's disease.

28 Nov 2013

EPCs: A promising therapy for type 1 diabetes

Pancreatic islet transplantation is a promising therapy for treating type 1 diabetes, but the majority of transplanted cells die soon after they are transplanted.

27 Nov 2013

AB SCIEX launches IVD-MS Analyzer CE marked for general in vitro diagnostic use in Europe

Continuing to rapidly expand its presence in the clinical diagnostics field, AB SCIEX, a global leader in analytical technologies, today announced the launch of its AB SCIEX IVD-MS™ Analyzer CE marked for general in vitro diagnostic use in Europe.*

27 Nov 2013

Bruker receives FDA clearance to market MALDI Biotyper CA System in the U.S.

Bruker Corporation today announced that it has been granted U.S. FDA clearance under Section 510(k) to market its MALDI Biotyper CA System in the United States for the identification of Gram negative bacterial colonies cultured from human specimens.

26 Nov 2013

ARMI reveals new insights into how cells organize and form an early mammalian embryo

In research published today in Nature Cell Biology, scientists from the EMBL Australia research team based at Monash University's Australian Regenerative Medicine Institute (ARMI) have revealed new insights into how cells organise and form an early mammalian embryo.

26 Nov 2013

Waseda University researchers observe molecular motors that play critical role in chromosome transport

Researchers at Waseda University in Japan have for the first time directly observed the “molecular motor”, called Xkid, that plays a critical role in facilitating the proper alignment of chromosomes during cell division. Their findings are expected to contribute greatly to elucidating the molecular mechanisms of chromosome segregation, a key aspect of the development of certain medical disorders including cancer and birth defects.

25 Nov 2013

Study: Oatmeal breakfast shows greater increase in appetite control than ready-to-eat cereal

While obesity is a complex and multifaceted problem, much of the strategy behind combating it boils down to healthy eating habits. Taking into account the primary role of subjective appetite sensations in said habits, a group of researchers recently compared the satiety impact of two popular breakfast choices: oatmeal and ready-to-eat breakfast cereal (RTEC).

25 Nov 2013

NYSCF partners with NIH to generate stem cell for treating rare diseases

In what is anticipated to be a major step forward for rare disease research, The New York Stem Cell Foundation (NYSCF) Research Institute is partnering with the National Institutes of Health (NIH) Undiagnosed Disease Program (UDP).

22 Nov 2013

Pharmaceutical powder characterisation and inhaler testing workshop to include expert presentations

A new workshop organised by Monash University will include invited presentations from Copley Scientific, the world’s leading provider of inhaler testing equipment, Freeman Technology, global leaders in the field of powder characterisation, and ATA Scientific, distributors of Malvern Panalytical materials characterisation systems.

From Malvern Panalytical 21 Nov 2013

Covagen, TRL expand research collaboration to generate bispecific FynomAb

Covagen and Tanabe Research Laboratories U.S.A, Inc., a fully owned subsidiary of Mitsubishi Tanabe Pharma Corporation, today announced that they expanded their strategic research collaboration. MTPC and TRL have nominated a first bispecific FynomAb for formal preclinical development which triggered an undisclosed milestone payment. MTPC and TRL also exercised an option for a second bispecific FynomAb program based on the parties' research and licensing agreement signed in October 2012.

21 Nov 2013

Using radiation models to improve cancer therapies: an interview with Adrian Treverton, COO of Xstrahl and Jean-Pierre Wery, President of Crown Bioscience

What we are trying to do is take a cancer model like the PDX model (patient-derived tumor xenograft), which is a human-derived cancer growing in an in vivo model and apply radiation to that model.

From Xstrahl 20 Nov 2013

NeutroPhase irrigation therapy and NPWT help treat severe flesh eating and wound infections

NovaBay Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company developing topical non-antibiotic antimicrobial products, today announced the publication of a scientific paper by Dr. John R. Crew of Seton Medical Center, Daly City, California, describing the first use of adjunctive NeutroPhase irrigation therapy in conjunction with Negative Pressure Wound Therapy to successfully manage the severely-infected wound in the arm of a patient with life-threatening 'flesh-eating' disease.

20 Nov 2013

in vitro News and Research

PrimeraDx gets FDA clearance for ICEPlex C. difficile Assay Kit and ICEPlex System

Researchers offer promise of strategy for curing HIV infection

New genetics promises to change faulty genes of future generations by using "designer sperm”

New finding links obesity and high-fat, high-sugar diets with changes in inflammatory status

EMD Serono's TocopheRx to focus on development of oral FSH agonists for infertility treatment

Cyclin D1 protein controls cell cycle progression, microRNA biogenesis in breast cancer

Patrys to present data from PAT-SM6 Phase I/IIa trial in multiple myeloma at ASH conference

Data from Patrys' PAT-SM6 Phase I/IIa trial in multiple myeloma to be presented at ASH Annual Meeting

Certain Chinese medicines can regulate neurotrophic and apoptosis-related factors

EPCs: A promising therapy for type 1 diabetes

AB SCIEX launches IVD-MS Analyzer CE marked for general in vitro diagnostic use in Europe

Bruker receives FDA clearance to market MALDI Biotyper CA System in the U.S.

ARMI reveals new insights into how cells organize and form an early mammalian embryo

Waseda University researchers observe molecular motors that play critical role in chromosome transport

Study: Oatmeal breakfast shows greater increase in appetite control than ready-to-eat cereal

NYSCF partners with NIH to generate stem cell for treating rare diseases

Pharmaceutical powder characterisation and inhaler testing workshop to include expert presentations

Covagen, TRL expand research collaboration to generate bispecific FynomAb

Using radiation models to improve cancer therapies: an interview with Adrian Treverton, COO of Xstrahl and Jean-Pierre Wery, President of Crown Bioscience

NeutroPhase irrigation therapy and NPWT help treat severe flesh eating and wound infections

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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