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New molecular and morphologic insights into chronic rejection after lung transplantation

A study of lung tissue from patients with end-stage bronchiolitis obliterans syndrome (BOS) as a complication of lung transplantation yielded molecular and morphologic insights into the development of chronic rejection.

3 Aug 2021

Biolabs LA at The Lundquist Institute reaches highly significant capacity milestone

BioLabs LA at The Lundquist Institute, a co-working and incubator facility for high-potential bioscience start-ups, has reached 100% capacity ahead of schedule.

3 Aug 2021

Start codon disruption with CRISPR-Cas9 gene editing prevents Fuchs’ corneal dystrophy in mice

In a new study, researchers at the University of Oregon's Phil and Penny Knight Campus for Accelerating Scientific Impact used start codon disruption with CRISPR-Cas9 gene editing to prevent Fuchs' corneal dystrophy in mice.

3 Aug 2021

Diagnosis of viral infections using micro and nanoscale technologies

In a recent study, the authors provide a review on both micro- and nanoscale technologies that advanced the diagnosis of viral diseases.

3 Aug 2021

Study shows COVID-19 organ-specific outcomes depend on anti-spike glycoprotein antibodies

A recent study from the University of Rochester reveals how the biodistribution kinetics and the affinity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for many different organs in the human body can be affected by antibodies targeting viral spike glycoprotein. The paper is currently available on the bioRxiv* preprint server while it undergoes peer review.

3 Aug 2021

Comprehensive review: Nanomaterial-based delivery vehicles for cancer vaccine development

Over the years, significant advancements in cancer research have led us to the next step in cancer therapy – vaccines for cancer! However, the direct use of these vaccines in the affected individuals have often failed to bring about desired anti-tumor effects.

3 Aug 2021

Lipid blast shield protects natural killer cells and also some cancer cells

A newly discovered fat 'shield' that prevents natural killer cells from being destroyed by their own deadly biological weapons also allows some cancer cells to evade an immune system attack, a study at Columbia University has found.

3 Aug 2021

Researchers discover brain's switching system used in information processing and storing of memories

A team of scientists has uncovered a system in the brain used in the processing of information and in the storing of memories--akin to how railroad switches control a train's destination. The findings offer new insights into how the brain functions.

3 Aug 2021

“Sybodies” protect against SARS-CoV-2 in hamster model

Researchers in China, The Netherlands, France, and Switzerland have identified synthetic nanobodies or “sybodies” that exhibit potent neutralizing activity against severe acute respiratory syndrome coronavirus (SARS-CoV-2) – the agent responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic.

3 Aug 2021

Study explores potential role of visual feedback of the tongue in speech motor learning

When we speak, although we may not be aware of it, we use our auditory and somatosensory systems to monitor the results of the movements of our tongue or lips.

3 Aug 2021

PROTEIN-ID project aims to develop a device able to generate identity card of proteins

A device able to generate proteins identity card: this is the ambitious goal of the "PROTEIN ID" project, funded by the European Union with about 3 million euro for the next 3 years and coordinated by the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology).

3 Aug 2021

Flagging potential molecular predictors of response to biological therapies in ulcerative colitis

Several individuals suffering from bowel diseases like ulcerative colitis fail to respond to conventionally used biologic therapies.

3 Aug 2021

Study suggests second Pfizer-BioNTech vaccine shot may not be needed after previous SARS-CoV-2 infection

Researchers in Austria have conducted a study showing that individuals previously infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibit a significantly more pronounced antibody response to one dose of Pfizer-BioNTech’s coronavirus disease 2019 (COVID-19) vaccine than previously uninfected individuals.

3 Aug 2021

Study shows increased risk of overdose and mental health crisis following opioid dose tapering

Opioid therapy is complex. In recent years, a rise in opioid-related deaths and changing prescribing guidelines and regulatory policies have led many physicians to reduce daily doses for patients prescribed stable opioid therapy for chronic pain.

3 Aug 2021

Innovative strategy for early diagnosis of schizophrenia

An innovative strategy that analyzes a region of the genome offers the possibility of early diagnosis of schizophrenia, reports a team led by researchers at Baylor College of Medicine.

3 Aug 2021

Discovery may enable the development of new therapies to kill aggressive cancer cells

Vanderbilt faculty and researchers are looking for the "Achilles' heel" of the cancer cells that survive initial chemotherapy.

3 Aug 2021

Resilience training for healthcare workers during the COVID-19 pandemic

Research carried out in the United States along with fourteen other countries suggested high rates of depression, anxiety, and acute stress reactions in healthcare workers during the COVID-19 pandemic. The healthcare workers were found to suffer from high levels of stress as they had to face increased clinical demands during this time and were cut off from essential sources of support.

3 Aug 2021

Study sheds light on oral vaccine failure in mouse model of chronic gut disorder

A chronic gut disorder that occurs in regions with poor sanitation disrupts intestinal immune responses and impairs oral vaccine effectiveness in a mouse model of the disease, according to research led by UPMC Children's Hospital of Pittsburgh and University of Pittsburgh School of Medicine scientists.

3 Aug 2021

Study shows pharmacological rescue of mitochondrial defect related to Parkinson's disease

Treating mice that have a Parkinson's disease-causing mutation with a small molecule compound restores the removal of damaged mitochondria from their brain cells, shows a study published today in eLife.

3 Aug 2021

Open-access database could speed up repurposing of old drugs as new treatments

Researchers have created a new open-access database of information on drug candidates and how they are metabolized by the body, which could help speed up the repurposing of old drugs as new treatments.

3 Aug 2021

Research News and Research

New molecular and morphologic insights into chronic rejection after lung transplantation

Biolabs LA at The Lundquist Institute reaches highly significant capacity milestone

Start codon disruption with CRISPR-Cas9 gene editing prevents Fuchs’ corneal dystrophy in mice

Diagnosis of viral infections using micro and nanoscale technologies

Study shows COVID-19 organ-specific outcomes depend on anti-spike glycoprotein antibodies

Comprehensive review: Nanomaterial-based delivery vehicles for cancer vaccine development

Lipid blast shield protects natural killer cells and also some cancer cells

Researchers discover brain's switching system used in information processing and storing of memories

“Sybodies” protect against SARS-CoV-2 in hamster model

Study explores potential role of visual feedback of the tongue in speech motor learning

PROTEIN-ID project aims to develop a device able to generate identity card of proteins

Flagging potential molecular predictors of response to biological therapies in ulcerative colitis

Study suggests second Pfizer-BioNTech vaccine shot may not be needed after previous SARS-CoV-2 infection

Study shows increased risk of overdose and mental health crisis following opioid dose tapering

Innovative strategy for early diagnosis of schizophrenia

Discovery may enable the development of new therapies to kill aggressive cancer cells

Resilience training for healthcare workers during the COVID-19 pandemic

Study sheds light on oral vaccine failure in mouse model of chronic gut disorder

Study shows pharmacological rescue of mitochondrial defect related to Parkinson's disease

Open-access database could speed up repurposing of old drugs as new treatments

A guide to advancing biotherapeutic research eBook

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Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology