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Scientists use nanodiamonds to boost delivery of drug to leukemic cells

By binding multiple molecules of a common leukemia drug with nanodiamonds, scientists from the National University of Singapore (NUS) and University of California, Los Angeles (UCLA) managed to boost the delivery of the drug to leukemic cells and retain the drug within the cells to combat the cancer.

11 Sep 2013

S&P Capital IQ commences Standard & Poor's Factual Stock Report coverage on Epigenomics AG

S&P Capital IQ announced today that it has commenced Standard & Poor's Factual Stock Report coverage on Epigenomics AG.

7 Sep 2013

Non-adherent bone marrow cell-derived mesenchymal stem cells could differentiate into neuronal-like cells

It is widely believed that bone marrow mesenchymal stem cells are highly adherent fibroblastic cells, defined as colony-forming unit-fibroblasts. Nevertheless, a few reports have shown that the non-adherent bone marrow cells can give rise to colony-forming unit-fibroblasts in vitro, and possess a certain differentiation potential.

6 Sep 2013

FIBRO-TARGETS project aims to identify mechanisms involved in MIF, define therapeutic approaches

Unravelling the mechanisms of cardiac fibrosis will lead to the discovery of therapeutic target candidates for various cardiac diseases. FIBRO-TARGETS brings together eleven European expert teams from six different countries both from public research institutes and European biotechs.

5 Sep 2013

Affinium initiates dosing in Phase 1 IV clinical trial of antibiotic prodrug, AFN-1720

Affinium Pharmaceuticals announced today that it has initiated dosing in a Phase 1 intravenous clinical trial of its new antibiotic prodrug, AFN-1720. AFN-1720 is the prodrug of the active drug, AFN-1252.

5 Sep 2013

Taconic To Promote And Sell Medicyte Hepatocyte Products

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4 Sep 2013

65 metabolites in urine simultaneously measured by clinical IEM-by-NMR screening study in Turkey

At the 12th International Congress of Inborn Errors of Metabolism (www.iciem2013.com), Bruker announces another milestone in the cost-effective use of NMR (nuclear magnetic resonance) spectroscopy screening as a clinical research tool for metabolic screening and small molecule in vitro diagnostics (IVD) research and validation.

4 Sep 2013

Study shows how stomach bacteria manipulates human immune system to survive in stomach

Helicobacter pylori is a bacterium that establishes a life-long stomach infection in humans, which in some cases can lead to duodenal ulcers or stomach cancer. New research, presented at this week's Society for General Microbiology Autumn Conference, gives us a clearer understanding of how these bacteria can manipulate the human immune system to survive in the mucosal lining of the stomach.

4 Sep 2013

Research shows how mucosal surfaces in body respond to C. albicans to prevent damage

Candida albicans is a common fungus found living in, and on, many parts of the human body. Usually this species causes no harm to humans unless it can breach the body's immune defences, where can lead to serious illness or death.

3 Sep 2013

IVF, cesarean section asthma link strengthened

Researchers from Greece have shown that pediatric asthma is associated with both conception by in vitro fertilization and birth by cesarean section.

29 Aug 2013

Reformulated OxyContin®: an interview with Dr. Paul Coplan, Executive Director, Risk Management and Epidemiology, Purdue Pharma

OxyContin contains oxycodone, which is an opioid agonist. It is used for the management of moderate to severe pain when a constant opioid analgesic is needed for a prolonged period of time.

29 Aug 2013

Researchers develop new opioid drug for chronic pain

A team of researchers led by Andrew Coop, PhD, professor and chair of the Department of Pharmaceutical Sciences at the University of Maryland School of Pharmacy, has developed a new opioid drug that shows great potential to advance treatment and improve quality of life for individuals living with chronic pain.

29 Aug 2013

Companion diagnostics: an interview with Trevor Hawkins, SVP, Strategy, Innovation and Business Development for Siemens Healthcare Diagnostics

Companion diagnostics is critical in helping to pave the way for personalized medicine, in which the treatment is adapted and precisely tailored to the patient.

From Siemens Healthineers 27 Aug 2013

Mount Sinai, Exosome Partner On Body Fluid Molecular Diagnostics

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22 Aug 2013

Drug oxytocin may contribute to postpartum bleeding, researchers find

With the number of maternal deaths on the rise in the United States, researchers found that a drug frequently used to augment or induce labor may contribute to postpartum bleeding, a study in the September issue of Anesthesiology notes.

22 Aug 2013

FDA approves first mass spectrometer system in U.S. for identification of bacteria, yeasts

The U.S. Food and Drug Administration today allowed marketing in the U.S. of the first mass spectrometer system for automated identification of bacteria and yeasts that are known to cause serious illness in humans.

22 Aug 2013

IBN researchers one step closer to viable tissue replacements

Researchers at the Institute of Bioengineering and Nanotechnology have developed a simple method of organizing cells and their microenvironments in hydrogel fibers. Their unique technology provides a feasible template for assembling complex structures, such as liver and fat tissues, as described in their recent publication in Nature Communications.

19 Aug 2013

Scientists reveal how females select 'right' sperm to fertilize their eggs

University of East Anglia scientists have revealed how females select the 'right' sperm to fertilize their eggs when faced with the risk of being fertilized by wrong sperm from a different species.

19 Aug 2013

Study suggests Braintone has neuroprotective effects on ischemia-induced brain damage

Recently, the importance of the neurovascular unit, which is comprised of neurons, endothelial cells and astrocytes, has received great attention in the field of stroke, because stroke affects not only neurons, but also astrocytes and microvessels.

17 Aug 2013

Scientists identify new therapeutic targets to inhibit progression of Alzheimer's disease

To stop the progression of Alzheimer's disease in the early stage, it is necessary to identify new therapeutic targets. Prof. Yunpeng Cao and team from the First Affiliated Hospital of China Medical University examined striatal-enriched phosphatase 61 expression in the brain tissues of Alzheimer's disease rats using in vivo and in vitro models, and analyzed the molecular mechanism by which striatal-enriched phosphatase 61 regulates N-methyl-D- aspartate receptor 2B transport.

17 Aug 2013

in vitro News and Research

Scientists use nanodiamonds to boost delivery of drug to leukemic cells

S&P Capital IQ commences Standard & Poor's Factual Stock Report coverage on Epigenomics AG

Non-adherent bone marrow cell-derived mesenchymal stem cells could differentiate into neuronal-like cells

FIBRO-TARGETS project aims to identify mechanisms involved in MIF, define therapeutic approaches

Affinium initiates dosing in Phase 1 IV clinical trial of antibiotic prodrug, AFN-1720

Taconic To Promote And Sell Medicyte Hepatocyte Products

65 metabolites in urine simultaneously measured by clinical IEM-by-NMR screening study in Turkey

Study shows how stomach bacteria manipulates human immune system to survive in stomach

Research shows how mucosal surfaces in body respond to C. albicans to prevent damage

IVF, cesarean section asthma link strengthened

Reformulated OxyContin®: an interview with Dr. Paul Coplan, Executive Director, Risk Management and Epidemiology, Purdue Pharma

Researchers develop new opioid drug for chronic pain

Companion diagnostics: an interview with Trevor Hawkins, SVP, Strategy, Innovation and Business Development for Siemens Healthcare Diagnostics

Mount Sinai, Exosome Partner On Body Fluid Molecular Diagnostics

Drug oxytocin may contribute to postpartum bleeding, researchers find

FDA approves first mass spectrometer system in U.S. for identification of bacteria, yeasts

IBN researchers one step closer to viable tissue replacements

Scientists reveal how females select 'right' sperm to fertilize their eggs

Study suggests Braintone has neuroprotective effects on ischemia-induced brain damage

Scientists identify new therapeutic targets to inhibit progression of Alzheimer's disease

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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