Immune Response News and Research

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New study shows link between gut bacteria and age-related chronic inflammation

A new study shows for the first time that gut bacteria from old mice induce age-related chronic inflammation when transplanted into young mice.

3 Nov 2017

Collaborative research identifies broadly cross-protective vaccines for H3N2 influenza

A collaborative research and development partnership between researchers at the University of Georgia and Sanofi Pasteur, the largest influenza vaccine manufacturer in the world, has resulted in the identification of a vaccine candidate that protects against multiple co-circulating strains of H3N2 influenza isolated over five seasons following testing in mouse and ferret models.

2 Nov 2017

First-of-its-kind nonsynthetic, decellularized graft one step closer to clinical trials

Researchers at the University of Minnesota have created a new lab-grown blood vessel replacement that is composed completely of biological materials, but surprisingly doesn't contain any living cells at implantation. The vessel, that could be used as an "off the shelf" graft for kidney dialysis patients, performed well in a recent study with nonhuman primates.

1 Nov 2017

GHIT Fund announces US$16.7 million to support development of new drugs, vaccines and diagnostics

The Global Health Innovative Technology Fund, a unique Japanese public-private partnership formed to battle infectious diseases around the globe, today announced US$16.7 million to support development of new compounds for fighting malaria and tuberculosis, a leishmaniasis vaccine and drug, and a treatment for a long-ignored flesh-eating infection.

31 Oct 2017

Stem cells do not participate directly in cartilage regeneration but serve to ‘animate’ the process

Stem cell therapy has great potential for curing cartilage damage. However, it has remained unclear whether stem cells are responsible for regeneration or whether they trigger the process.

31 Oct 2017

Researchers uncover surprising immune cell activity that may explain limitations of immunotherapy

Researchers have uncovered a surprising process within a key immune cell that may help explain the limitations of immunotherapy as a cancer treatment.

31 Oct 2017

CureVac begins phase I study to assess intratumoral application of RNAdjuvant technology in patients with solid tumors

CureVac AG, a fully-integrated biotechnology company pioneering mRNA-based drugs, today announced it has initiated a Phase I study assessing the intratumoral application of its novel RNAdjuvant technology in patients with superficial solid tumors that are easily accessible for repeated intratumoral injections. RNAdjuvant is designed to amplify the scope and quality of an immune response when used alone or in combination with other immune therapies.

28 Oct 2017

Longevity Biotech receives award to evaluate novel drug candidate for MS in preclinical models

Longevity Biotech, Inc. has received an award from the National Multiple Sclerosis Society through Fast Forward, the Society's commercial research funding program, to evaluate LBT-3627 in preclinical models as a potential disease-modifying therapeutic agent.

28 Oct 2017

University of Colorado’s second shingles vaccine approved by FDA

The Centers for Disease Control's Advisory Committee on Immunization Practices recommended new treatment practices Wednesday for shingles based on a vaccine initially developed at the University of Colorado Health Sciences Center, now the University of Colorado Anschutz Medical Campus.

28 Oct 2017

Novel molecule holds potential to become part of successful HIV vaccine

Researchers at the University of Maryland and Duke University have designed a novel protein-sugar vaccine candidate that, in an animal model, stimulated an immune response against sugars that form a protective shield around HIV. The molecule could one day become part of a successful HIV vaccine.

27 Oct 2017

AACI, CDC, and ACS honor pediatricians who adopt effective HPV vaccination practices

Today the Association of American Cancer Institutes, the American Cancer Society, Inc., and the Centers for Disease Control and Prevention's National Center for Immunization and Respiratory Diseases announced 10 award winners as part of its HPV Vaccine Is Cancer Prevention campaign.

27 Oct 2017

Regional anesthesia for breast cancer surgery patients associated with better outcomes

Physicians believe that the use of regional anesthesia is associated with lower levels of inflammation and a better immune response in breast cancer surgery patients.

26 Oct 2017

Genetic variability of Helicobacter pylori complicates efforts to develop effective vaccine

Helicobacter pylori is a widespread bacterial pathogen that infects the lining of the stomach, where it can cause ulcers and even cancer. As a new study shows, its genetic variability complicates efforts to develop an effective vaccine.

25 Oct 2017

Lung microbiome plays major role in asthma severity and response to treatment

While the microbiome has gained significant attention for its impact on digestive health in recent years, its effect on lung disease has largely remained unstudied.

24 Oct 2017

KU Leuven researchers identify new rapid response mechanism against bacterial infections

When bacteria enter our body, they kick-start a powerful immune response. But this chain of reactions doesn't fully account for our immediate responses. Researchers at KU Leuven, Belgium, show that so-called ion channels play a key role as 'first responders'.

23 Oct 2017

E-cigarettes may activate distinctive and potentially damaging immune responses, study reveals

A new study, published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine, suggests that e-cigarettes may stimulate distinct immune responses along with the same responses that cigarettes stimulate resulting in lung disease.

23 Oct 2017

Study offers solution to protect against vaccine-enhanced respiratory disease

Researchers have discovered that a virus-like particle vaccine can prime the body's immune response and prevent the severe respiratory disease that results when patients given an early form of a vaccine for respiratory syncytial virus (RSV) are exposed to RSV, according to a study led by Georgia State University.

23 Oct 2017

Study provides deeper understanding on mechanisms of lipid-based autoimmune disease

Phospholipids - fat molecules that form the membranes found around cells - make up almost half of the dry weight of cells, but when it comes to autoimmune diseases, their role has largely been overlooked.

20 Oct 2017

New vaccine for pneumonia holds promise to save thousands of lives

In 2004, pneumonia killed more than 2 million children worldwide, according to the World Health Organization. By 2015, the number was less than 1 million.

20 Oct 2017

Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation

It has been amply proven that smoking can cause serious diseases such as emphysema and cancer. A new study, however, shows that pharmacological stimulation of a specific type of nicotinic receptor in cells of the immune system could be a strategy to treat inflammatory lung disease.

20 Oct 2017

Immune Response News and Research

New study shows link between gut bacteria and age-related chronic inflammation

Collaborative research identifies broadly cross-protective vaccines for H3N2 influenza

First-of-its-kind nonsynthetic, decellularized graft one step closer to clinical trials

GHIT Fund announces US$16.7 million to support development of new drugs, vaccines and diagnostics

Stem cells do not participate directly in cartilage regeneration but serve to ‘animate’ the process

Researchers uncover surprising immune cell activity that may explain limitations of immunotherapy

CureVac begins phase I study to assess intratumoral application of RNAdjuvant technology in patients with solid tumors

Longevity Biotech receives award to evaluate novel drug candidate for MS in preclinical models

University of Colorado’s second shingles vaccine approved by FDA

Novel molecule holds potential to become part of successful HIV vaccine

AACI, CDC, and ACS honor pediatricians who adopt effective HPV vaccination practices

Regional anesthesia for breast cancer surgery patients associated with better outcomes

Genetic variability of Helicobacter pylori complicates efforts to develop effective vaccine

Lung microbiome plays major role in asthma severity and response to treatment

KU Leuven researchers identify new rapid response mechanism against bacterial infections

E-cigarettes may activate distinctive and potentially damaging immune responses, study reveals

Study offers solution to protect against vaccine-enhanced respiratory disease

Study provides deeper understanding on mechanisms of lipid-based autoimmune disease

New vaccine for pneumonia holds promise to save thousands of lives

Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation

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