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BGI, CITIC-XIANGYA successfully apply NGS to detect IVF embryos with genetic abnormalities

The largest genomic institute of the world, BGI Shenzhen, China, together with Reproductive & Genetic Hospital CITIC-XIANGYA announced today that they have successfully applied Next Generation Sequencing to detect in vitro fertilized embryos with genetic abnormalities.

24 Jul 2013

NIH awards $1.7M grant to develop effective treatments for brain disorders

Ten percent of Americans experience a seizure in their lifetime, with three million diagnosed with epilepsy, a chronic neurological disorder. Anticonvulsant medications can mitigate the hyperactivity of neurons that leads to seizures, but not without severe side effects, including cognitive impairment.

23 Jul 2013

Bacillus-derived Hyaluronic acid from Novozymes Biopharma, Hyasis®, increases in vitro drug release time from under 10 minutes to approximately 15 hours

An investigation undertaken by Novozymes Biopharma DK has shown that when the corticosteroid dexamethasone is formulated in a cross-linked Hyaluronic acid (HA) hydrogel, the drug’s in vitro release time increases from under 10 minutes to approximately 15 hours. In addition, the in vivo half-life of dexamethasone is shown to plateau with stable dexamethasone concentration up to four hours after injection.

22 Jul 2013

HemoShear announces milestone in development of predictive drug safety systems

HemoShear, LLC, a leading developer of human-relevant systems for drug development and discovery, today announced an important milestone in the development of systems that predict safety of new drugs and chemicals.

19 Jul 2013

Oncodesign receives AAALAC certification for Dijon-based research center

Oncodesign, a contract research laboratory for the discovery of new anticancer therapies, today announces that its Dijon-based research center has received AAALAC certification.

18 Jul 2013

CHOP-led research increases numbers of patients who could be treated with gene therapy

Gene therapy researchers have produced a bioengineered decoy that fools the immune system and prevents it from mistakenly defeating the benefits delivered by a corrective gene.

18 Jul 2013

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

Scientists at the University of Massachusetts Medical School are the first to establish that a naturally occurring X chromosome "off switch" can be rerouted to neutralize the extra chromosome responsible for trisomy 21, also known as Down syndrome, a genetic disorder characterized by cognitive impairment.

18 Jul 2013

State highlights: Poll says N.C. abortion bill hurting Governor support

A selection of health policy stories from North Carolina, California and Virginia.

18 Jul 2013

Drug that spurs cancer cells to self-destruct is on road to human clinical trials

Thanks to a new $2 million investment, a drug that spurs cancer cells to self-destruct while sparing healthy cells is on the road to human clinical trials. The compound, known as PAC-1, has so far proven safe and has promising anti-cancer effects in cell culture, in mouse models of cancer and in pet dogs with spontaneously occurring lymphomas and osteosarcomas.

18 Jul 2013

North Dakota judge strikes down state law on nonsurgical abortion drugs

The state judge issues an opinion from an April trial. In the meantime, new abortion and "personhood" proposals in that state rankle some medical professionals.

17 Jul 2013

Study explores mechanisms of chemotherapy-induced neurological side effects

Chemotherapy is one of the primary treatments for cancer. However, one of the most disturbing findings of recent studies of cancer survivors is the apparent prevalence of chemotherapy-associated adverse neurological effects, including vascular complications, seizures, mood disorders, cognitive dysfunctions, and peripheral neuropathies.

16 Jul 2013

FDA approves Gilotrif for patients with late stage non-small cell lung cancer

Companion test also approved to identify appropriate patients The U.S. Food and Drug Administration today approved Gilotrif (afatinib) for patients with late stage (metastatic) non-small cell lung cancer (NSCLC) whose tumors express specific types of epidermal growth factor receptor (EGFR) gene mutations, as detected by an FDA-approved test. Lung cancer is the leading cause of cancer-related death among men and women.

16 Jul 2013

Semi-quantitative pregnancy tests: an interview with Dr. Paul Blumenthal, Stanford University School of Medicine

Regular pregnancy tests work a little bit like a simple light switch that you have on your wall. It’s either on or off. When it’s on, that means the test is positive; if it’s off, obviously, it’s negative.

12 Jul 2013

UC Riverside professor receives grant to study potential treatment for age-related macular degeneration

A University of California, Riverside bioengineering professor has received a two-year, $120,000 grant to search for chemical compounds that have the potential to treat age-related macular degeneration.

12 Jul 2013

PrenaTest can be now performed for high risk pregnancies after ninth week

PrenaTest, Europe's first non-invasive molecular genetic blood test to determine fetal trisomies 13, 18 and 21 in the mother's blood can now be performed for high risk pregnancies after the ninth week (W 9 + D 0).

11 Jul 2013

Cancer immunotherapies promise to be a new tool in fight against cancer

Drugs that direct a cancer patient's immune system to eradicate her or his disease, known as cancer immunotherapies, promise to be a new tool in the fight against cancer. Since the Koch Institute's inception, exploring the close relationship between the immune system and cancer has been one of the Institute's priority research areas.

9 Jul 2013

New low-cost method of in-vitro fertilization may help infertile couples in developing countries

A new low-cost method of in-vitro fertilization developed at the University of Colorado Boulder that performed successfully in recent human clinical trials in Belgium may help thousands of infertile couples in developing countries.

9 Jul 2013

VBL Therapeutics publishes VB-201 pre-clinical data in journal of Atherosclerosis

VBL Therapeutics, a clinical-stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, announced today the publication of pre-clinical data for VB-201 in the journal of Atherosclerosis.

8 Jul 2013

Study: ChemoFx chemoresponse assay can help identify platinum resistance in primary ovarian cancer

Precision Therapeutics, a leading life-science company dedicated to the improvement of patient outcomes in personalized medicine, today announced findings that support the ChemoFx chemoresponse assay as a tool to aid in the identification of platinum resistance in primary ovarian cancer, according to a presentation at the Annual Meeting of The Western Association of Gynecologic Oncologists June 26-29, in Seattle, Washington.

8 Jul 2013

Probiodrug to present studies on PQ912 for treatment of Alzheimer's disease at AAIC meeting

Probiodrug AG (Probiodrug) announced that it will be making two poster and two oral presentations at the upcoming Alzheimer's Association International Conference in Boston, MA July 13 - 18, 2013.

8 Jul 2013

in vitro News and Research

BGI, CITIC-XIANGYA successfully apply NGS to detect IVF embryos with genetic abnormalities

NIH awards $1.7M grant to develop effective treatments for brain disorders

Bacillus-derived Hyaluronic acid from Novozymes Biopharma, Hyasis®, increases in vitro drug release time from under 10 minutes to approximately 15 hours

HemoShear announces milestone in development of predictive drug safety systems

Oncodesign receives AAALAC certification for Dijon-based research center

CHOP-led research increases numbers of patients who could be treated with gene therapy

Discovery provides evidence that genetic defect responsible for Down syndrome can be suppressed

State highlights: Poll says N.C. abortion bill hurting Governor support

Drug that spurs cancer cells to self-destruct is on road to human clinical trials

North Dakota judge strikes down state law on nonsurgical abortion drugs

Study explores mechanisms of chemotherapy-induced neurological side effects

FDA approves Gilotrif for patients with late stage non-small cell lung cancer

Semi-quantitative pregnancy tests: an interview with Dr. Paul Blumenthal, Stanford University School of Medicine

UC Riverside professor receives grant to study potential treatment for age-related macular degeneration

PrenaTest can be now performed for high risk pregnancies after ninth week

Cancer immunotherapies promise to be a new tool in fight against cancer

New low-cost method of in-vitro fertilization may help infertile couples in developing countries

VBL Therapeutics publishes VB-201 pre-clinical data in journal of Atherosclerosis

Study: ChemoFx chemoresponse assay can help identify platinum resistance in primary ovarian cancer

Probiodrug to present studies on PQ912 for treatment of Alzheimer's disease at AAIC meeting

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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