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KeyBank Foundation announces $2 million grant for Cleveland Clinic, CWRU for integrated learning model

The KeyBank Foundation has announced a grant of $2 million to Cleveland Clinic and Case Western Reserve University (CWRU) which will support a combined effort to enhance and expand medical students' interprofessional education experiences.

9 Jun 2015

Novel virtual laboratory works to improve population health, prepare future transformational leaders

A newly published paper describes and evaluates the Indiana University Center for Health Innovation and Implementation Science, a novel virtual laboratory employing the tools of implementation science to improve population health, lower costs of its delivery and prepare the future health care transformational leaders.

9 Jun 2015

Duration of antibiotic treatment can be cut by half for complicated abdominal infections

In a finding important for preventing the development of antibiotic-resistant superbugs, researchers at the University of Virginia School of Medicine and 22 other institutions have determined that the duration of antibiotic treatment for complicated abdominal infections can be cut by half and remain equally effective.

9 Jun 2015

New study suggests link between lower life satisfaction and sleep problems during midlife

A new study suggests that lower life satisfaction is linked to sleep problems during midlife. Respondents with higher life satisfaction reported shorter sleep onset latency (SOL). Sleep onset delay among those with low life satisfaction could be the result of worry and anxiety, as reported elsewhere. These findings support the idea that life satisfaction is interlinked with many measures of sleep and sleep quality, suggesting that improving one of these variables might result in improving the other.

9 Jun 2015

Severe restless legs syndrome associated with increased risk of stroke

A new study suggests that increased restless legs syndrome (RLS) severity is associated with subsequent increased risk of stroke.

9 Jun 2015

UC Davis funds BRAIN-STIM program to uncover potential treatments for neurodegenerative disorders

In 2013, President Obama announced the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, unveiling plans to make a bold investment to understand the human mind with the intent to uncover ways to prevent, treat and cure brain disorders like Alzheimer's, autism, and epilepsy.

9 Jun 2015

Weight loss reduces asthma severity in obese adults, finds study

A Canadian study published in the June issue of the journal CHEST found weight loss reduced asthma severity as measured by airway hyperresponsiveness (AHR) in obese adults.

9 Jun 2015

Glucose-control drug sitagliptin does not raise risk of cardiovascular events

A clinical trial of the glucose-control drug sitagliptin among patients with type 2 diabetes and established cardiovascular disease has found it did not raise the risk of major adverse cardiovascular events.

9 Jun 2015

Despite low value and high costs, certain preoperative tests still common in U.S.

Professional physician associations consider certain routine tests before elective surgery to be of low value and high cost, and have sought to discourage their utilization.

9 Jun 2015

Study: Children with TBI more likely to experience daytime sleepiness, sleep disturbances

A new study suggests that children with traumatic brain injuries (TBI) have poorer sleep and more daytime sleepiness in comparison to healthy children.

9 Jun 2015

Protective antibody response could be effective in preventing mother-to-child HIV transmission

How most babies are protected from acquiring HIV from their infected mothers has been a matter of scientific controversy.

9 Jun 2015

Enhancing body's gut defense system can reverse bloodstream infections

An upset in the body's natural balance of gut bacteria that may lead to life-threatening bloodstream infections can be reversed by enhancing a specific immune defense response, UT Southwestern Medical Center researchers have found.

9 Jun 2015

Findings could lead to new therapies that stop breast cancer progression

Scientists have discovered a trigger that allows breast cancer cells to spread to the lungs. They have found that blocking the signals in mice with breast cancer greatly reduces the number of secondary tumours found in the lungs.

9 Jun 2015

Cell fusion triggers multiple genetic changes that convert normal cells to cancer cells

Although there is no one established universal cause of cancer, genetic changes are central to its development. The accumulation of spontaneous genetic changes, or mutations, that occur when cells divide can be hastened by exposure to carcinogens such as cigarette smoke (lung cancer) and infectious agents such as the papillomavirus (cervical cancer).

9 Jun 2015

Sanofi announces results from Phase IIIb ELIXA study of Lyxumia in adults with diabetes and high CV risk

Sanofi announced today the presentation of full results of the Phase IIIb ELIXA study, which was designed to assess the cardiovascular (CV) safety of Lyxumia (lixisenatide) in adults with type 2 diabetes and high CV risk.

8 Jun 2015

Jazz enrolls first patients in JZP-110 Phase 3 study for treatment of EDS in patients with narcolepsy or OSA

Jazz Pharmaceuticals plc announced today that the first patients have been enrolled in a Phase 3 clinical development program evaluating the safety and efficacy of its investigational drug candidate, JZP-110, as a wake-promoting agent in the treatment of excessive daytime sleepiness (EDS) in adult patients with narcolepsy or with obstructive sleep apnea (OSA).

8 Jun 2015

Results from Intarcia's two phase 3 clinical trials of ITCA 650 to be presented at ADA's Scientific Session

Intarcia Therapeutics, Inc. today announced the presentation of results from its first two phase 3 clinical trials (FREEDOM-1 and FREEDOM-1 HBL) of its late-stage investigational candidate ITCA 650 (exenatide delivered continuously via a small matchstick-size subcutaneous osmotic mini-pump just once or twice yearly) at the 75th Scientific Sessions of the American Diabetes Association.

8 Jun 2015

Clinical data of Trovagene's Precision Cancer Monitoring platform to be presented at two medical conferences

Trovagene, Inc., a developer of cell-free molecular diagnostics, announced today that clinical data featuring its Precision Cancer MonitoringSM platform will be presented at the 2015 Cancer Markers and Liquid Biopsies conference in San Diego, CA on June 11-12, and at the AACR Precision Medicine Series: Integrating Clinical Genomics and Cancer Therapy in Salt Lake City, UT on June 13-16.

8 Jun 2015

Celtaxsys closes $40M Series D financing and receives $5M CFFT grant to conduct CTX-4430 Phase 2 trial

Celtaxsys, Inc., a clinical stage drug development company focused on developing novel therapies for inflammatory diseases, today announced the successful completion of a $40M Series D financing led by Domain Partners VIII. Additional investors in the financing include Lumira Capital, RMI Partners, Masters Capital Management and the Georgia Research Alliance Venture Fund.

8 Jun 2015

DalCor, MHI partner to conduct Phase III clinical trial of investigational cardiovascular drug

DalCor Pharmaceuticals and the Montreal Heart Institute announced today a collaboration in principle to conduct an international Phase III clinical trial which could result in a major clinical advance in cardiovascular personalised medicine.

8 Jun 2015

Medicine News and Research

KeyBank Foundation announces $2 million grant for Cleveland Clinic, CWRU for integrated learning model

Novel virtual laboratory works to improve population health, prepare future transformational leaders

Duration of antibiotic treatment can be cut by half for complicated abdominal infections

New study suggests link between lower life satisfaction and sleep problems during midlife

Severe restless legs syndrome associated with increased risk of stroke

UC Davis funds BRAIN-STIM program to uncover potential treatments for neurodegenerative disorders

Weight loss reduces asthma severity in obese adults, finds study

Glucose-control drug sitagliptin does not raise risk of cardiovascular events

Despite low value and high costs, certain preoperative tests still common in U.S.

Study: Children with TBI more likely to experience daytime sleepiness, sleep disturbances

Protective antibody response could be effective in preventing mother-to-child HIV transmission

Enhancing body's gut defense system can reverse bloodstream infections

Findings could lead to new therapies that stop breast cancer progression

Cell fusion triggers multiple genetic changes that convert normal cells to cancer cells

Sanofi announces results from Phase IIIb ELIXA study of Lyxumia in adults with diabetes and high CV risk

Jazz enrolls first patients in JZP-110 Phase 3 study for treatment of EDS in patients with narcolepsy or OSA

Results from Intarcia's two phase 3 clinical trials of ITCA 650 to be presented at ADA's Scientific Session

Clinical data of Trovagene's Precision Cancer Monitoring platform to be presented at two medical conferences

Celtaxsys closes $40M Series D financing and receives $5M CFFT grant to conduct CTX-4430 Phase 2 trial

DalCor, MHI partner to conduct Phase III clinical trial of investigational cardiovascular drug

Everything there is to know about biosimilars eBook

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

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