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$Matched therapy and FoundationOne genomic profiling improve outcomes in patients with refractory cancer$

Matched therapy and FoundationOne genomic profiling improve outcomes in patients with refractory cancer

Foundation Medicine, Inc. and collaborators from the University of Texas MD Anderson Cancer Center and Sarah Cannon Research Institute at HealthOne today announced compelling new data demonstrating that matching patients to targeted therapies based on the unique molecular profile of the patient’s advanced cancer leads to improved outcomes across a variety of key measures, including overall survival.

2 Jun 2015

Maintenance therapy with lenalidomide benefits patients with multiple myeloma

A large cooperative-group study directed by the Alliance for Clinical Trials in Oncology has confirmed previous evidence that the drug lenalidomide delays time to disease progression for patients with multiple myeloma and is an important treatment option for patients with this rare but increasingly common cancer of the blood and marrow.

2 Jun 2015

ASCO 2015: Novartis presents data on Zykadia and Tafinlar studies for non-small cell lung cancer

Novartis today announced new data from two Phase II studies of Zykadia (ceritinib), as well as one Phase II study of Tafinlar® (dabrafenib) in combination with Mekinist (trametinib) in certain patients with non-small cell lung cancer.

2 Jun 2015

AstraZeneca announces efficacy and safety data for AZD9291 in first-line treatment of EGFRm advanced NSCLC

AstraZeneca today announced preliminary efficacy and safety data for AZD9291 in the first-line treatment of epidermal growth factor receptor mutation positive (EGFRm) advanced non-small cell lung cancer (NSCLC).

2 Jun 2015

Phase 2 results from Abbvie’s veliparib study in NSCLC presented at ASCO 2015

AbbVie, a global biopharmaceutical company, today announced findings from a Phase 2 study of the investigational medicine veliparib combined with the chemotherapy regimen carboplatin and paclitaxel that showed an improvement in median progression-free survival (PFS) in patients with previously untreated metastatic or advanced non-small cell lung cancer (NSCLC) who are current smokers.

2 Jun 2015

New data underscores the importance of FoundationOne genomic profiling for treatment of biliary tract cancers

Foundation Medicine, Inc. today presented new data including promising clinical outcomes underscoring the importance of integrating comprehensive genomic profiling with FoundationOne® into clinical oncology care for the treatment of biliary tract cancers.

2 Jun 2015

Consumer Reports announces commitment to help wipe out 'superbugs'

Consumer Reports, the world's largest and most trusted nonprofit consumer organization, today announced its commitment to help wipe out antibiotic-resistant bacteria or "superbugs." Infections related to the use of antibiotics sicken about 2.25 million Americans each year and kill 37,000, according to the Centers for Disease Control and Prevention.

2 Jun 2015

Genetically-programmed probiotics could help detect liver cancer metastases early-on

Scientists at the University of California, San Diego and the Massachusetts Institute of Technology have described a new method for detecting liver cancer metastases in mice. The approach uses over-the-counter probiotics genetically programmed to produce signals easily detectable in urine when liver cancer metastases are present.

2 Jun 2015

Substantial pharmacogenetic information available on cardiovascular drugs

There is a wealth of published information describing interactions between drugs used to treat cardiovascular disease and the genetic variations that can affect how patients respond to them. But few heart specialists make routine use of this potentially life-saving data.

2 Jun 2015

Veritas Genetics introduces genetic screen for hereditary breast and ovarian cancer risk

Boston-based Veritas Genetics is launching its mission to disrupt the genetic testing industry and bring personalized medicine and prevention to the forefront, allowing individuals to take more control of their health.

2 Jun 2015

Study addresses children's basic perspectives on living with Type 1 diabetes

If a picture is worth a thousand words, UF Health Type 1 diabetes researchers and their colleagues have tapped into an encyclopedia, revealing new insights into how young people cope with the disease.

2 Jun 2015

New tool kit aims to support family planning efforts

In developing regions where the economy is weak and medical services are limited, global health experts say as many as 200 million women want access to long-term, reversible contraceptives to avoid unintended pregnancies and to help space out the births of their children.

2 Jun 2015

NCCN to host policy summit on emerging issues in tissue allocation

Tissue allocation is a growing issue of concern for many researchers due, in part, to expanding research interests in precision medicine. The increased demand by pharmaceutical and biotech companies for patient tissue specimens collected for clinical care and trials presents clinical, ethical, and legal issues.

2 Jun 2015

Philips to highlight range of Magnetic Resonance solutions at 23rd ISMRM

Royal Philips today announced the range of its Magnetic Resonance (MR) solutions to be showcased at the International Society for Magnetic Resonance in Medicine's (ISMRM) 23rd Annual Meeting & Exhibition in Toronto, Canada.

2 Jun 2015

Researchers identify previously unknown gene mutation that causes achromatopsia

People with achromatopsia, an inherited eye disorder, see the world literally in black and white. Worse yet, their extreme sensitivity to light makes them nearly blind in bright sunlight. Now, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health System have identified a previously unknown gene mutation that underlies this disorder.

2 Jun 2015

Zinc levels linked to formation of kidney stone

New research on kidney stone formation reveals that zinc levels may contribute to kidney stone formation, a common urinary condition that can cause excruciating pain. The research found that zinc may be the core by which stone formation starts.

2 Jun 2015

VBL Therapeutics reports positive results from VB-111 Phase 1/2a study in recurrent platinum-resistant Müllerian cancer

VBL Therapeutics, a late-stage clinical biotechnology company focused on the discovery, development and commercialization of first-in-class treatments for cancer, today announced positive interim results from an investigator-initiated, Phase 1/2a trial of multiple dose VB-111 in recurrent platinum-resistant Müllerian (ovarian) cancer.

2 Jun 2015

Novartis CTL019 CAR T cell therapy demonstrates potential to treat B-cell lymphomas

Novartis is highlighting data from an ongoing Phase II clinical study of CTL019, an investigational chimeric antigen receptor (CAR) T cell therapy, that indicate its potential in the treatment of specific types of hard-to-treat non-Hodgkin lymphoma.

2 Jun 2015

U.S. states with stronger alcohol policies have lower rates of youth drinking

A new study by Boston University and Boston Medical Center researchers reveals that U.S. states with stronger alcohol policies have lower rates of youth overall drinking and binge drinking. The study's results, published in the journal Pediatrics, further suggest that the link is largely a result of policies intended mostly for adults and their effects on reducing adult binge drinking.

2 Jun 2015

Chronic exposure to bacteria may lead to development of Type 2 diabetes

Bacteria and viruses have an obvious role in causing infectious diseases, but microbes have also been identified as the surprising cause of other illnesses, including cervical cancer (Human papilloma virus) and stomach ulcers (H. pylori bacteria).

2 Jun 2015

Medicine News and Research

Matched therapy and FoundationOne genomic profiling improve outcomes in patients with refractory cancer

Maintenance therapy with lenalidomide benefits patients with multiple myeloma

ASCO 2015: Novartis presents data on Zykadia and Tafinlar studies for non-small cell lung cancer

AstraZeneca announces efficacy and safety data for AZD9291 in first-line treatment of EGFRm advanced NSCLC

Phase 2 results from Abbvie’s veliparib study in NSCLC presented at ASCO 2015

New data underscores the importance of FoundationOne genomic profiling for treatment of biliary tract cancers

Consumer Reports announces commitment to help wipe out 'superbugs'

Genetically-programmed probiotics could help detect liver cancer metastases early-on

Substantial pharmacogenetic information available on cardiovascular drugs

Veritas Genetics introduces genetic screen for hereditary breast and ovarian cancer risk

Study addresses children's basic perspectives on living with Type 1 diabetes

New tool kit aims to support family planning efforts

NCCN to host policy summit on emerging issues in tissue allocation

Philips to highlight range of Magnetic Resonance solutions at 23rd ISMRM

Researchers identify previously unknown gene mutation that causes achromatopsia

Zinc levels linked to formation of kidney stone

VBL Therapeutics reports positive results from VB-111 Phase 1/2a study in recurrent platinum-resistant Müllerian cancer

Novartis CTL019 CAR T cell therapy demonstrates potential to treat B-cell lymphomas

U.S. states with stronger alcohol policies have lower rates of youth drinking

Chronic exposure to bacteria may lead to development of Type 2 diabetes

Everything there is to know about biosimilars eBook

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

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