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Blocking IL-11 signaling can promote liver regeneration after paracetamol-induced damage

Scientists at Duke-NUS Medical School and National Heart Centre Singapore, in collaboration with colleagues in Singapore and the UK, have shown that the human form of the signaling protein interleukin 11 (IL-11) has a damaging effect on human liver cells--overturning a prior hypothesis that it could help livers damaged by paracetamol poisoning.

18 Jun 2021

Deep learning could transform the ability to accurately interpret HIV test results

Pioneering technology developed by UCL and Africa Health Research Institute researchers could transform the ability to accurately interpret HIV test results, particularly in low- and middle-income countries.

18 Jun 2021

Novel vaccine based on mRNA technology protects against malaria in animal models

Scientists from the Walter Reed Army Institute of Research and Naval Medical Research Center partnered with researchers at the University of Pennsylvania and Acuitas Therapeutics to develop a novel vaccine based on mRNA technology that protects against malaria in animal models, publishing their findings in npj Vaccines.

18 Jun 2021

Study paves the way for development of new therapeutics for C. difficile infection

A new study paves the way for the development of next generation therapeutics for the prevention and treatment of Clostridioides difficile infection (CDI), the most frequent cause of healthcare-acquired gastrointestinal infections and death in developed countries.

18 Jun 2021

Common blood pressure drug not effective in reducing hospitalization for mildly-ill COVID-19 outpatients

University of Minnesota Medical School researchers determined that the common blood pressure medication, losartan, is not effective in reducing hospitalization for mildly-ill COVID-19 outpatients.

18 Jun 2021

Study explores COVID-19 outcomes in people with RA

Arani Vivekanantham and colleagues investigated the association between RA and the risk of COVID-19 diagnosis, hospitalization with COVID-19,and COVID-19-related death.

18 Jun 2021

Staged alert system helped prevent hospital surges, long COVID-19 lockdowns in Austin

A staged alert system, designed by scientists and public health officials to guide local policies, helped one city prevent hospital surges and long lockdowns, according to new research published in the journal Nature Communications.

18 Jun 2021

New hydrogel prevents the formation of adhesions after cardiac surgery

A hydrogel that forms a barrier to keep heart tissue from adhering to surrounding tissue after surgery was developed and successfully tested in rodents by a team of University of California San Diego researchers.

18 Jun 2021

Study provides insight into factors that may contribute to men's suicide vulnerability

Colorado State University Professor of Psychology Silvia Sara Canetto has spent many years researching patterns and meanings of suicide by culture, trying to make sense of the variability in women's and men's suicide mortality around the world.

18 Jun 2021

KHN’s ‘What the Health?’: The ACA lives

For the third time in nine years, the Affordable Care Act has survived a constitutional challenge at the Supreme Court. In a 7-2 decision, the court ruled that the states and individuals who filed the latest challenge lacked standing to sue.

18 Jun 2021

Could a fungus-derived compound reduce hyperinflammation in severe COVID-19?

New research from scientists at the University of Pennsylvania, USA, demonstrates that cyclosporine A (CSA), a calcineurin inhibitor that modulates cytokine production, may have potential antiviral properties against coronaviruses.

18 Jun 2021

Breathonix 60-Second COVID-19 Breath Test Powered by IONICON

Roll-out of PTR-TOF breath test with provisional authorization in Singapore.

From Ionicon Analytik Ges.m.b.H. 18 Jun 2021

COVID-19 outbreak in Mauritius dominated by new SARS-CoV-2 variant B.1.1.318

Underlining the key role of genomic surveillance in keeping tabs on the spread of SARS-CoV-2, a new medRxiv* preprint shows how a new variant called B.1.1.318 rose to dominance in the small island country of Mauritius, in the Indian Ocean.

18 Jun 2021

Could horse-derived antibody therapy be effective against SARS-CoV-2 variants of concern?

A new study, released as a preprint on the bioRxiv* server, reveals the high neutralizing efficacy of hyperimmune horse serum against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This could prove, if validated, to be a more affordable yet potent therapeutic in reducing the morbidity and mortality caused by this virus.

18 Jun 2021

First insights into human prion disease could help tackle neurodegenerative diseases

Surface features of human prions have been identified for the first time, which may provide key information into treatments of neurodegenerative diseases.

18 Jun 2021

Fighting the good fight –a new protein found in red blood cells linked to limiting cognitive decline

A new study shows that depleting mouse blood of the protein ADORA2B led to faster declines in memory, and increased brain inflammation.

18 Jun 2021

The hard realities of a ‘no jab, no job’ mandate for health care workers

Christopher Richmond keeps a running tab on how many workers at the ManorCare skilled nursing facility he manages in western Pennsylvania have rolled up their sleeves for a covid-19 vaccine.

18 Jun 2021

Convalescent plasma associated with better survival in blood cancer patients with COVID-19

Convalescent plasma therapy was associated with better survival in blood cancer patients hospitalized with COVID-19, especially in sicker patients. The findings by the COVID-19 and Cancer Consortium (CCC19) are newly published in the peer-reviewed journal JAMA Oncology.

18 Jun 2021

Study highlights need to address the mental health of new fathers

While postpartum depression in new mothers is well recognized and known to increase if the newborn requires intensive care, depression in new fathers has not received much attention.

18 Jun 2021

Printable biosensor enables simultaneous recording and imaging of tissues, organs during surgery

Surgeons may soon be able to localize critical regions in tissues and organs during a surgical operation thanks to a new, patent-pending Purdue University biosensor that can be printed in 3D using an automated printing system.

18 Jun 2021

Research News and Research

Blocking IL-11 signaling can promote liver regeneration after paracetamol-induced damage

Deep learning could transform the ability to accurately interpret HIV test results

Novel vaccine based on mRNA technology protects against malaria in animal models

Study paves the way for development of new therapeutics for C. difficile infection

Common blood pressure drug not effective in reducing hospitalization for mildly-ill COVID-19 outpatients

Study explores COVID-19 outcomes in people with RA

Staged alert system helped prevent hospital surges, long COVID-19 lockdowns in Austin

New hydrogel prevents the formation of adhesions after cardiac surgery

Study provides insight into factors that may contribute to men's suicide vulnerability

KHN’s ‘What the Health?’: The ACA lives

Could a fungus-derived compound reduce hyperinflammation in severe COVID-19?

Breathonix 60-Second COVID-19 Breath Test Powered by IONICON

COVID-19 outbreak in Mauritius dominated by new SARS-CoV-2 variant B.1.1.318

Could horse-derived antibody therapy be effective against SARS-CoV-2 variants of concern?

First insights into human prion disease could help tackle neurodegenerative diseases

Fighting the good fight –a new protein found in red blood cells linked to limiting cognitive decline

The hard realities of a ‘no jab, no job’ mandate for health care workers

Convalescent plasma associated with better survival in blood cancer patients with COVID-19

Study highlights need to address the mental health of new fathers

Printable biosensor enables simultaneous recording and imaging of tissues, organs during surgery

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