Anti Inflammatory News and Research

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Salicylate an active metabolite of aspirin - weakens lipid membranes

It's well known that high doses of aspirin can cause ulcers and temporary deafness, but the biochemical mechanism responsible for these phenomena has never been deciphered.

19 Sep 2005

Nuclear receptor proteins could change anti-inflammatory treatments

Several nuclear receptor proteins appear to overlap in their ability to exert anti-inflammatory effects, according to new research by scientists at the University of California, San Diego (UCSD).

12 Sep 2005

Double whammy of vitamin D and anti-inflammatory zaps prostate cancer cells

Scientists from Stanford University say they have discovered that vitamin D, known as the "sunshine vitamin,"can limit the growth of prostate cancer cells when combined with non-steroidal anti-inflammatory drugs.

6 Sep 2005

IP 751 a marijuana-derived drug effectively suppresses pain and bladder overactivity in hypersensitive bladder disorders

IP 751, a potent synthetic analog of a metabolite of THC-the principal active ingredient of marijuana-effectively suppresses pain and bladder overactivity in hypersensitive bladder disorders such as interstitial cystitis (IC), according to animal model study results presented today at the annual meeting of the International Continence Society.

1 Sep 2005

Pomegranate fruit extracts can block enzymes that contribute to osteoarthritis

The study looked at the ability of an extract of pomegranate fruit against Interleukin-1b (IL-1b), a pro-inflammatory protein molecule that plays a key role in cartilage degradation in osteoarthritis.

1 Sep 2005

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs, taken in combination, have been shown to act as a powerful one-two punch that knocks down the growth of prostate cancer cells.

1 Sep 2005

Extra-virgin olive oil tastes good and is also an anti-inflammatory

After a tasting experience at a molecular gastronomy meeting in Sicily, biologist Gary Beauchamp of Pennsylvania University decided to analyse freshly pressed extra-virgin olive oil and found a chemical that acted like ibuprofen in the oil.

31 Aug 2005

Relative of the celebrated COX-2 inhibitor celecoxib is tough tumor fighter

A close structural relative of the celebrated COX-2 inhibitor celecoxib (brand name: Celebrex) is a potent tumor fighter, able to wipe out tumor cells that are resistant to conventional chemotherapies, according to an interdisciplinary team of researchers from the University of Southern California.

29 Aug 2005

Taking aspirin longterm could reduce colorectal cancer risk

According to new report from the Nurses' Health Study (NHS), regular, long-term aspirin use can significantly reduce the risk of colorectal cancer.

24 Aug 2005

Aspirin use can significantly reduce the risk of colorectal cancer

A new report from the Nurse's Health Study finds that regular, long-term aspirin use can significantly reduce the risk of colorectal cancer, as suggested by several earlier studies.

23 Aug 2005

Epidemiological study links heart protection with non-aspirin, non-steroidal drugs

It is well known that aspirin, a non-selective, non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX), reduces the risk of heart attack and stroke.

22 Aug 2005

Common non-aspirin painkillers linked to high blood pressure in women

Women who consume higher doses of non-aspirin painkillers are much more likely to develop high blood pressure than women who do not use them, according to research reported in Hypertension: Journal of the American Heart Association.

17 Aug 2005

New study shows even non-prescription painkillers raise blood pressure in women

According to a new U.S. study women who take higher doses of common, over-the-counter painkillers, such as Ibuprofen and even Tylenol, have higher blood pressure than women who do not.

16 Aug 2005

Plasma exchange treatment shown most helpful for severe attacks in subtype of MS patients

A Mayo Clinic study demonstrates that only those multiple sclerosis (MS) patients with evidence for antibody deposition or complement activation -- immune cells that can cause tissue destruction -- in their lesions are likely to respond to plasma exchange, a treatment for acute MS attacks.

11 Aug 2005

Roflumilast could become a new therapeutic strategy for patients with chronic obstructive pulmonary disease

An anti-inflammatory drug called roflumilast could become a new therapeutic strategy for patients with chronic obstructive pulmonary disease (COPD), conclude the results of a randomised trial in this week’s issue of The Lancet.

11 Aug 2005

Little convincing evidence that dietary antioxidant supplements such as vitamin E prevent heart disease

Instead there has been a surprise finding, which relates to a synthetic antioxidant, the drug Probucol, which is no longer prescribed in Australia.

11 Aug 2005

Latest findings on aspirin resistance

Treatment failures occur with any drug and aspirin is no exception. Evidence is growing that some people will not respond to the anti-coagulant action of aspirin and the drug will not protect against cardiovascular events despite its regular intake.

9 Aug 2005

Omega-6 fatty acids promote the growth of prostate tumor cells in the laboratory

A study conducted at the San Francisco VA Medical Center (SFVAMC) has demonstrated that omega-6 fatty acids such as the fat found in corn oil promote the growth of prostate tumor cells in the laboratory.

2 Aug 2005

Anti-inflammatory function of Alzheimer's disease drugs revealed

The mechanism in anti-Alzheimer's disease drugs that inhibits the production of a destructive, inflammation-causing protein in the brain has been revealed by researchers at the Hebrew university of Jerusalem.

28 Jul 2005

Loyola researchers hope that zoledronic acid will be effective and safe for patients with inflammatory bowel diseases (IBD)

Researchers at the Osteoporosis and Metabolic Bone Disease Center and the Division of Gastroenterology at Loyola University Health System are studying a once-yearly, 15-minute infusion of an intravenous (IV) medication in patients with osteopenia (low bone mass) and inflammatory bowel diseases (IBD) that, if proven effective, may be considered the standard of treatment.

26 Jul 2005

Anti Inflammatory News and Research

Salicylate an active metabolite of aspirin - weakens lipid membranes

Nuclear receptor proteins could change anti-inflammatory treatments

Double whammy of vitamin D and anti-inflammatory zaps prostate cancer cells

IP 751 a marijuana-derived drug effectively suppresses pain and bladder overactivity in hypersensitive bladder disorders

Pomegranate fruit extracts can block enzymes that contribute to osteoarthritis

Low doses of the active form of vitamin D and non-steroidal anti-inflammatory drugs form one-two punch against prostate cancer cells

Extra-virgin olive oil tastes good and is also an anti-inflammatory

Relative of the celebrated COX-2 inhibitor celecoxib is tough tumor fighter

Taking aspirin longterm could reduce colorectal cancer risk

Aspirin use can significantly reduce the risk of colorectal cancer

Epidemiological study links heart protection with non-aspirin, non-steroidal drugs

Common non-aspirin painkillers linked to high blood pressure in women

New study shows even non-prescription painkillers raise blood pressure in women

Plasma exchange treatment shown most helpful for severe attacks in subtype of MS patients

Roflumilast could become a new therapeutic strategy for patients with chronic obstructive pulmonary disease

Little convincing evidence that dietary antioxidant supplements such as vitamin E prevent heart disease

Latest findings on aspirin resistance

Omega-6 fatty acids promote the growth of prostate tumor cells in the laboratory

Anti-inflammatory function of Alzheimer's disease drugs revealed

Loyola researchers hope that zoledronic acid will be effective and safe for patients with inflammatory bowel diseases (IBD)

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