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SuperGen closes acquisition of Astex

SuperGen, Inc., a pharmaceutical company dedicated to the discovery and development of novel cancer therapies, announced it has closed the transaction to acquire Astex Therapeutics Limited, a privately held, UK-based biotechnology company developing targeted therapies.

21 Jul 2011

Diabetes gene linked to Alzheimer’s

Researchers from Mount Sinai School of Medicine have identified a gene that causes diabetes kills nerve cells in the brain, possibly resulting in Alzheimer’s disease.

20 Jul 2011

MDL announces HPV-16 Status reflex test

Medical Diagnostic Laboratories, L.L.C. (MDL) is a CLIA certified infectious disease laboratory which specializes in high-complexity, state-of-the-art, automated DNA-based molecular analyses.

20 Jul 2011

Young people with serious genetic blood disorder are not getting right help at school

A new study suggests young people with a serious genetic blood disorder are not getting the right help at school, especially pupils who miss lessons due to sickness.

20 Jul 2011

New insights into sleep difficulties among older people

A new study of the brain's master circadian clock - known as the suprachiasmatic nucleus, or SCN - reveals that a key pattern of rhythmic neural activity begins to decline by middle age. The study, whose senior author is UCLA Chancellor Gene Block, may have implications for the large number of older people who have difficulty sleeping and adjusting to time changes.

20 Jul 2011

Cord Blood Bank of Arkansas opens at UAMS

Celebrating the grand opening of the Cord Blood Bank of Arkansas at the University of Arkansas for Medical Sciences (UAMS) today, Brian and Jennifer Odle told how the use of cord blood gave their 18-month-old daughter a new lease on life.

20 Jul 2011

Scientists discover new dominant gene linked to Parkinson's

The newly discovered gene is known as VPS35, the sixth one which has been associated with Parkinson's disease and the third dominant gene.

20 Jul 2011

U.S. News ranks Mount Sinai Medical Center among America's Best Hospitals for 2011-2012

Mount Sinai Medical Center is among the nation's top hospitals for the fifth year in a row according to U.S. News & World Report's 2011-2012 Best Hospitals. Mount Sinai was the only hospital in South Florida to receive a prestigious national ranking in geriatric care and one of only three hospitals in South Florida to rank on a national level.

20 Jul 2011

Medco announces new offerings within Advanced Oncology Solutions

Medco Health Solutions, Inc. today announced new offerings within its Advanced Oncology Solutions, that include treatment pathways decision support with embedded pharmacogenomic testing and nutrition recommendations for cancer patients.

20 Jul 2011

Chemotherapy combined with anti-cancer agent shows promise for treatment of aggressive breast cancers

Some of the most aggressive forms of breast cancer are more vulnerable to chemotherapy when it is combined with a new class of anti-cancer agent, researchers from the Walter and Eliza Hall Institute have shown.

20 Jul 2011

Normal stem cell encourages growth of cancer stem cells and fuels ovarian cancer

Researchers at the University of Michigan Comprehensive Cancer Center have found that a type of normal stem cell fuels ovarian cancer by encouraging cancer stem cells to grow.

20 Jul 2011

Hallmark of cancer cells

Scientists from the Hebrew University have identified the molecular basis for DNA breakage, a hallmark of cancer cells. The findings of this research have just been published in the journal Molecular Cell.

20 Jul 2011

New technology for processing human waste in developing countries

The Bill & Melinda Gates Foundation has awarded Delft University of Technology, a grant to 'Reinvent the toilet'. Aim of this project is to develop new technology for processing human waste without links to water, energy, or sewer lines, and at costs affordable to the poor in developing countries.

20 Jul 2011

Investigational compound dapagliflozin receives negative recommendation from FDA Advisory Committee

Bristol-Myers Squibb Company and AstraZeneca today reported the outcome of the U.S. Food and Drug Administration's (FDA) Endocrinologic and Metabolic Drugs Advisory Committee meeting on the New Drug Application for the investigational compound dapagliflozin.

20 Jul 2011

Possible new drug targets for treating diffuse large B-cell lymphoma

Researchers at the University of Maryland School of Medicine have discovered a novel interaction between two proteins involved in regulating cell growth that could provide possible new drug targets for treating diffuse large B-cell lymphoma, the most common type of non-Hodgkin's lymphoma.

20 Jul 2011

People with small hippocampus do not face higher risk of depression

Imaging studies have repeatedly found that people with depression have smaller hippocampal volumes than healthy individuals. The hippocampus is a brain region involved in learning and memory, spatial navigation, and the evaluation of complex life situations or "contexts".

20 Jul 2011

New transgenic mouse could predict toxicity of targeted cancer drugs

Only one in twenty cancer drugs makes its way from the laboratory to become an approved pharmaceutical product. The majority of new agents are only shown to be unsuitable in the later phases of clinical development which would explain the exorbitantly high development costs of 500 to 600 million euros per new cancer drug.

20 Jul 2011

Millennium submits VELCADE sNDA to FDA to add OS data for previously untreated multiple myeloma

Millennium: The Takeda Oncology Company with its parent company Takeda Pharmaceutical Company Limited today announced the submission of a supplemental New Drug Application (sNDA) with the U.S. Food and Drug Administration for VELCADE® (bortezomib) for injection to add overall survival data after a five-year follow up to the product label.

20 Jul 2011

Nuclear Factor I/B appears to drive progression of small cell lung cancer

A major challenge for cancer biologists is figuring out which among the hundreds of genetic mutations found in a cancer cell are most important for driving the cancer's spread.

20 Jul 2011

Gel Company, Biomerix partner to market and distribute 3D Scaffold

Biomerix Corporation and Gel Company today announced a strategic distribution agreement for the Biomerix 3D Scaffold, a novel three-dimensional tissue scaffold. Under the agreement, Gel Company will market and distribute the Biomerix 3D Scaffold to researchers in the life science community across the United States.

20 Jul 2011