Immune Response News and Research

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New high-throughput approach yields libraries of probes for immunological assays

An immunological test known as a "tetramer assay" can detect T cells in a blood sample that recognize a specific antigen.

20 Apr 2020

New research gives further evidence that autoimmunity plays a role in Parkinson's disease

A new study adds increasing evidence that Parkinson's disease is partly an autoimmune disease.

20 Apr 2020

Computer simulations yield promising vaccine candidate against SARS-CoV-2

In a recent study that appeared on a preprint server bioRxiv, scientists from India designed a multi-epitope peptide-based vaccine that predicted high immunogenic response in the population.

19 Apr 2020

Salk scientists uncover surprising role of tuft cells in pancreatitis

Persistent inflammation of the pancreas (chronic pancreatitis) is a known risk factor for developing pancreatic cancer, the third-deadliest cancer in the United States.

18 Apr 2020

UC San Diego Health launches serological tests to detect past exposure to novel coronavirus

Clinical laboratory physicians and scientists at UC San Diego Health have launched a pair of serological tests that will look for novel coronavirus antibodies -- evidence in persons tested that they have previously been infected by SARS-CoV-2, the viral cause of COVID-19, even if they never experienced tell-tale symptoms.

18 Apr 2020

Nasal smear as screening test for allergic rhinitis

Stuffy noses, itching and fits of sneezing - 130 million people in Europe suffer from hay fever and other forms of allergic rhinitis. Until now, these conditions have typically been diagnosed using blood samples or skin prick tests.

17 Apr 2020

Researchers discover unique structure and function of rotavirus VP3 protein

After eluding researchers for more than 30 years, the VP3 protein of rotavirus has finally revealed its unique structure and function to a team led by scientists at Baylor College of Medicine.

17 Apr 2020

URMC launches new coronavirus study to examine immune response

The University of Rochester Medical Center is launching a new study to understand how the body's immune system responds to COVID-19, including if and when a person could be re-infected with the virus and whether some people have pre-existing immunity.

17 Apr 2020

Gimsilumab trial starts in first US patient with ARDS and COVID-19

The first American patient with COVID-19 and acute respiratory distress syndrome (ARDS) has been put on the drug gimsilumab at Temple University Hospital, as part of the BREATHE clinical trial. The trial, sponsored by Roivant Sciences, will evaluate the effectiveness of intravenous gimsilumab in preventing death in patients with COVID-19 and ARDS.

16 Apr 2020

Gold-containing drug auranofin kills 95% of SARS-CoV-2 virus in 48 hours in lab conditions

A drug called auranofin, approved for the treatment of rheumatoid arthritis, effectively inhibits severe acute respiratory syndrome coronavirus (SARS-CoV-2) in laboratory conditions, as described in a new study by Georgia State University researchers.

16 Apr 2020

Specialized proteins could soak up excess cytokines in COVID-19 patients

One of the defining features of Covid-19 is the excessive immune response that can occur in severe cases. This burst of immune overreaction, also called a cytokine storm, damages the lungs and can be fatal.

16 Apr 2020

Octapharma USA supports new COVID-19 clinical trial

Octapharma USA is supporting a new investigator initiated clinical trial led by George Sakoulas, M.D. of Sharp Memorial Hospital in San Diego, California focused on treating the most critical patients at the heart of the coronavirus pandemic, those experiencing respiratory failure who become ventilator dependent.

16 Apr 2020

Entamoeba gingivalis linked to severe and recurrent periodontitis

For the first time, researchers from Charité - Universitätsmedizin Berlin have shown that a unicellular parasite commonly found in the mouth plays a role in both severe tissue inflammation and tissue destruction.

16 Apr 2020

Researchers explore how probiotic Bifidobacteria could help celiac disease patients

Gluten is enemy No. 1 for those with celiac disease, and it's hard to avoid. Episodes of this chronic autoimmune illness can be triggered by ingesting gluten, a key protein in wheat and some other grains.

15 Apr 2020

'Chaperone protein' protects against autoimmune diseases, mice study shows

Like a parent of teenagers at a party, Mother Nature depends on chaperones to keep one of her charges, the immune system, in line so that it doesn't mistakenly attack normal cells, tissues and organs in our bodies.

15 Apr 2020

Researchers decode how immune sensor plays role in defending cells against intruders

Until now, the immune sensor TLR8 has remained in the shadows of science. A research team led by the University of Bonn has now discovered how this sensor plays an important role in defending human cells against intruders.

15 Apr 2020

Discovery of T cells response spectrum could new shed light on immune diseases

The discovery that immune T cells have a spectrum of responsiveness could shed light on how our immune system responds to infections and cancer, and what goes wrong in immune diseases.

15 Apr 2020

The race is on for a coronavirus vaccine, 70 candidates, 3 at human trial stage

Amid the coronavirus disease (COVID-19) global pandemic that is infecting millions of people across the globe, hope sparks as the World Health Organization (WHO) reports that seventy vaccination trials for the novel coronavirus are underway, with three already at the human trial stage.

14 Apr 2020

Stray dogs possible origin of COVID-19 pandemic

After tracing coronavirus signatures in different species, a new research article published in the journal Molecular Biology and Evolution shows that stray dogs (more specifically dog intestines) may have acted as the origin of current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic.

14 Apr 2020

New vaccine for Chikungunya reported safe and well-tolerated

A virus-like particle vaccine was shown to be safe and well-tolerated among a healthy adult population living in chikungunya endemic areas, the researchers report in a new study published in the Journal of the American Medical Association (JAMA).

14 Apr 2020