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Researchers discover Foxj1 genetic 'conductor' responsible for new brain cell production

A team of North Carolina State University researchers has discovered more about how a gene connected to the production of new brain cells in adults does its job. Their findings could pave the way to new therapies for brain injury or disease.

30 Jun 2011

Brain stem cells shown to generate multiple new brain stem cells

A Johns Hopkins team has discovered in young adult mice that a lone brain stem cell is capable not only of replacing itself and giving rise to specialized neurons and glia – important types of brain cells – but also of taking a wholly unexpected path: generating two new brain stem cells.

30 Jun 2011

Golden Meditech total turnover increases 15% to HK$328,066,000 for year ended 31 March, 2011

Golden Meditech Holdings Limited, a leading integrated healthcare enterprise in China, is pleased to announce the Group's annual results for the year ended 31 March, 2011.

30 Jun 2011

Serum-free media with growth factors can improve MSCs' cell fate regulation

Mensenchymal stem cells (MSCs), multipotent cells identified in bone marrow and other tissues, have been shown to be therapeutically effective in the immunosuppression of T-cells, the regeneration of blood vessels, assisting in skin wound healing, and suppressing chronic airway inflammation in some asthma cases.

30 Jun 2011

Sensitivity of bladder cancer cells linked to chemotherapy and expression of miR-34a gene

Researchers at the UC Davis Cancer Center have discovered a way of sensitizing muscle-invasive bladder cancer cells so that they succumb to the toxic effects of chemotherapy. The finding adds to mounting evidence that tiny strands of RNA - called microRNA - play key roles in some of the deadliest types of cancer.

30 Jun 2011

UNC study uses optogenetics to tweak brain wiring responsible for drug addiction behaviors

Using a combination of genetic engineering and laser technology, researchers at the University of North Carolina at Chapel Hill have manipulated brain wiring responsible for reward-seeking behaviors, such as drug addiction.

30 Jun 2011

Glia plays key role in preventing progression of Rett Syndrome symptoms

A paper published online today in Nature reveals that glia play a key role in preventing the progression of the most prominent Rett Syndrome symptoms displayed by mouse models of the disease: lethality, irregular breathing and apneas, hypoactivity and decreased dendritic complexity.

30 Jun 2011

Cell Therapeutics to sell $30 million of Preferred Stock and warrants in registered offering

Cell Therapeutics, Inc. today announced that it has entered into an agreement to sell, subject to customary closing conditions, $30 million of shares of its Series 13 Preferred Stock and warrants to purchase shares of its common stock in a registered offering to six institutional investors.

30 Jun 2011

Mary Ann Liebert peer-reviewed journal highlights advances in gene therapy for neurological diseases

Novel tools and methods for delivering therapeutic genes to cells in the central nervous system hold great promise for the development of new treatments to combat incurable neurologic diseases.

30 Jun 2011

STSI joins JAX consortium to develop targeted cancer therapies

The Scripps Translational Science Institute (STSI) of San Diego, Calif., has joined a national consortium of research institutions headed by The Jackson Laboratory (JAX) that is building a library of primary human tumors with the goal of developing highly targeted cancer therapies.

30 Jun 2011

Researchers develop way to uncover evolution of human cancer cells

A team of researchers led by scientists at the University of California, San Francisco has developed a way to uncover the evolution of human cancer cells, determining the order in which mutations emerge in them as they wend their way from a normal, healthy state into invasive, malignant masses.

30 Jun 2011

FDA's ODAC recommends withdrawal of Avastin approval for metastatic breast cancer

Genentech, a member of the Roche Group, announced today that, during a U.S. Food and Drug Administration (FDA) hearing, the FDA's Oncologic Drugs Advisory Committee (ODAC) recommended that the FDA withdraw its approval of Avastin in combination with paclitaxel chemotherapy for previously untreated HER2-negative metastatic breast cancer.

30 Jun 2011

Dendreon receives FDA approval for Los Angeles cancer immunotherapy manufacturing facility

Dendreon Corporation today announced that the U.S. Food and Drug Administration approved its Los Angeles cancer immunotherapy manufacturing facility, allowing the company to continue to increase the availability of PROVENGE across the U.S. to help meet the needs of patients with asymptomatic or minimally symptomatic metastatic castrate resistant prostate cancer.

30 Jun 2011

Acetylon to advance ACY-1215 drug candidate with $27M Series B Preferred equity investment round of financing

Acetylon Pharmaceuticals, Inc. announced today that it has completed a $27 million Series B Preferred equity investment round of financing.

29 Jun 2011

RxMD and GlycoRegImmune enter drug development collaboration

RxMD, Inc., a privately-held, global therapeutics development company, today announced a collaboration agreement with GlycoRegImmune Inc. (GRI) to develop new treatments for inflammatory, autoimmune, and neurodegenerative conditions based on GRI's novel natural killer (NK) T cell targeted technologies.

29 Jun 2011

Zalicus commences Synavive SYNERGY Phase 2b clinical trial for rheumatoid arthritis

Zalicus Inc. a biopharmaceutical company that discovers and develops novel treatments for patients suffering from pain and immuno-inflammatory diseases today announced the initiation of the SYNERGY trial, a Phase 2b clinical trial evaluating Synavive, a low-dose glucocorticoid with the potential for amplified immuno-inflammatory benefits, in patients with rheumatoid arthritis (RA).

29 Jun 2011

GenSpera and University of Copenhagen collaborate on 'Sustainable Production of Thapsigargin using Light'

GenSpera, Inc. has entered into a cooperation agreement with the University of Copenhagen, in Copenhagen, Denmark, to collaborate on the "SPOTLight" (Sustainable Production of Thapsigargin using Light) project.

29 Jun 2011

Threshold commences combination Phase 1/2 trial of TH-302 and sunitinib for RCC, GIST and PNET

Threshold Pharmaceuticals, Inc., today announced the initiation of a Phase 1/2 dose escalation clinical trial of TH-302 in combination with sunitinib in patients with advanced renal cell carcinoma (RCC), gastrointestinal stromal tumor (GIST) and pancreatic neuroendocrine tumor (PNET).

29 Jun 2011

FamilyCord launches advanced cord tissue stem cell processing and storage

FamilyCord, one of the nation's leading cord blood banks, today announced their latest contribution to the advancement of the umbilical cord blood and tissue storage industry: CordTissuePlus.

29 Jun 2011

DMI completes rHEALTH sensor reduced-gravity experiments for NASA FAST program

In September 2010, the DNA Medicine Institute (DMI) successfully completed reduced-gravity experiments on its rHEALTH sensor for the NASA Facilitated Access to the Space Environment for Technology (FAST) program. NASA recently followed that experiment with a $190,000 contract to DMI to analyze data from the parabolic flights.

29 Jun 2011

Cell News and Research

Researchers discover Foxj1 genetic 'conductor' responsible for new brain cell production

Brain stem cells shown to generate multiple new brain stem cells

Golden Meditech total turnover increases 15% to HK$328,066,000 for year ended 31 March, 2011

Serum-free media with growth factors can improve MSCs' cell fate regulation

Sensitivity of bladder cancer cells linked to chemotherapy and expression of miR-34a gene

UNC study uses optogenetics to tweak brain wiring responsible for drug addiction behaviors

Glia plays key role in preventing progression of Rett Syndrome symptoms

Cell Therapeutics to sell $30 million of Preferred Stock and warrants in registered offering

Mary Ann Liebert peer-reviewed journal highlights advances in gene therapy for neurological diseases

STSI joins JAX consortium to develop targeted cancer therapies

Researchers develop way to uncover evolution of human cancer cells

FDA's ODAC recommends withdrawal of Avastin approval for metastatic breast cancer

Dendreon receives FDA approval for Los Angeles cancer immunotherapy manufacturing facility

Acetylon to advance ACY-1215 drug candidate with $27M Series B Preferred equity investment round of financing

RxMD and GlycoRegImmune enter drug development collaboration

Zalicus commences Synavive SYNERGY Phase 2b clinical trial for rheumatoid arthritis

GenSpera and University of Copenhagen collaborate on 'Sustainable Production of Thapsigargin using Light'

Threshold commences combination Phase 1/2 trial of TH-302 and sunitinib for RCC, GIST and PNET

FamilyCord launches advanced cord tissue stem cell processing and storage

DMI completes rHEALTH sensor reduced-gravity experiments for NASA FAST program

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