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Local anesthetic procaine inhibits SARS-CoV-2 in vitro

Research has shown that procaine and procaine-hydrochloride can reduce replication of SARS-CoV-2 and influenza A viruses in infected cells and reduce the production of cytokines by the viruses, making them potentially useful for treating COVID-19.

10 Jun 2021

New article explains the pros and cons of nasal vaccines

Vaccines are mostly synonymous with needles, an efficient and effective way to provide immunity to myriad infections. As COVID-19 vaccination efforts roll out across the U.S. and the world, some experts believe that a vaccine administered through the nose could be just as effective and easier to administer.

10 Jun 2021

Study offers new perspective on disproportionate impact of COVID-19

A new analysis by researchers at Massachusetts General Hospital (MGH) offers a novel perspective on the disproportionate impact that COVID-19 has had on people of color, low-income populations, and other structurally disadvantaged groups.

10 Jun 2021

Deep neural network model can accurately predict the brain age of healthy patients

A study shows that a deep neural network model can accurately predict the brain age of healthy patients based on electroencephalogram data recorded during an overnight sleep study, and EEG-predicted brain age indices display unique characteristics within populations with different diseases.

10 Jun 2021

Rapamycin targets gut cells to alter the way DNA is stored

Our genetic material is stored in our cells in a specific way to make the meter-long DNA molecule fit into the tiny cell nucleus of each body cell.

10 Jun 2021

Free virtual event highlights new inventions on point-of-care medical technologies

Life sciences entrepreneurs, researchers and investors working to shape the future of point-of-care medical technologies will gather next week for a free virtual event that will highlight new inventions and connect participants to resources to advance their work.

10 Jun 2021

Study: 20% of patients with unexplained sudden cardiac death have rare genetic variants

As many as 450,000 Americans die every year from a sudden, fatal heart condition, and in slightly more than one in ten cases the cause remains unexplained even after an autopsy.

9 Jun 2021

Efforts to prevent smoking, obesity could delay the need for angioplasty and stenting

Smokers needed their blocked arteries fixed nearly a decade earlier than non-smokers, and patients with obesity underwent these procedures four years earlier than non-obese patients, according to a new statewide study.

9 Jun 2021

Socially engaged older women higher odds of experiencing emotional abuse or mistreatment

For older adults, participating in social activities can protect against physical and mental signs of aging, but it may also pose risks, especially for women.

9 Jun 2021

High sensation-seeking personality trait confers susceptibility to drug addiction

People who have a high sensation-seeking personality trait may be more likely to develop an addiction to cocaine, according to a Rutgers study.

9 Jun 2021

New X-ray scanner could revolutionize cancer surgery, pathology, drug inspection

Engineers at Duke University have demonstrated a prototype X-ray scanning machine that reveals not just the shape of an object but its molecular composition. With unprecedented resolution and accuracy, the technology could revolutionize a wide range of fields such as cancer surgery, pathology, drug inspection and geology.

9 Jun 2021

Study reports on the immunogenicity of single-shot COVID-19 vaccine against SARS-CoV-2 variants

In the three months since Johnson & Johnson's COVID-19 vaccine received emergency use authorization from the U.S. Food and Drug Administration, more than 10 million Americans have received the vaccine, according to the Centers for Disease Control and Prevention.

9 Jun 2021

Cysteine persulfide found to be a new culprit in antibacterial resistance

A joint research project based in Kumamoto University, Japan has developed a new, highly sensitive analytical method that can detect degraded β-lactam antibacterial agents used in the treatment of bacterial infections.

9 Jun 2021

Nose-to-brain: Nasal delivery of biopharmaceuticals to the brain

Placing medications as close as possible to the site of the disease: This sounds completely believable in theory, but is unfortunately not so simple in practice. While this works well for many drugs via the bloodstream or the digestive tract, it does not apply to the brain.

9 Jun 2021

Trained dogs can accurately identify COVID-19 by scent

An interesting new medRxiv* preprint reveals that with careful training, the exquisite scent sensitivity of dogs may be exploited to rule out the presence of coronavirus disease 2019 (COVID-19) in human beings in real-time.

9 Jun 2021

Review of COVID-19's long-term effects

In a recent study, Canadian researchers documented the prevalence of post-COVID-19 conditions 4-12 weeks (short-term) and >12 weeks (long-term), by conducting a systematic review of peer-reviewed literature. This work is posted to the medRxiv* preprint server.

9 Jun 2021

Warmer conditions are not enough to prevent COVID-19 transmission, research shows

New research shows transmission of the virus behind COVID-19 varies seasonally, but warmer conditions are not enough to prevent transmission.

9 Jun 2021

Study: COVID-19 vaccines safe for IBD patients

Patients with inflammatory bowel diseases (IBD) do not appear to have increased risk of side effects from the Pfizer or Moderna COVID-19 vaccines, according to a recent Cedars-Sinai study published online and upcoming in print in the American Journal of Gastroenterology.

9 Jun 2021

Research clarifies neuron-specific DNA methylation changes and characteristics in bipolar disorder

A research collaboration based in Kumamoto University, Japan has revealed the DNA methylation status of gene transcriptional regulatory regions in the frontal lobes of patients with bipolar disorder (BD).

9 Jun 2021

FDA releases draft guidance on measuring patient-reported outcomes in cancer clinical trials

The following quote is attributed to Richard Pazdur, M.D., director of the FDA's Oncology Center of Excellence and acting director of the Office of Oncologic Diseases in the FDA's Center for Drug Evaluation and Research.

9 Jun 2021

Research News and Research

Local anesthetic procaine inhibits SARS-CoV-2 in vitro

New article explains the pros and cons of nasal vaccines

Study offers new perspective on disproportionate impact of COVID-19

Deep neural network model can accurately predict the brain age of healthy patients

Rapamycin targets gut cells to alter the way DNA is stored

Free virtual event highlights new inventions on point-of-care medical technologies

Study: 20% of patients with unexplained sudden cardiac death have rare genetic variants

Efforts to prevent smoking, obesity could delay the need for angioplasty and stenting

Socially engaged older women higher odds of experiencing emotional abuse or mistreatment

High sensation-seeking personality trait confers susceptibility to drug addiction

New X-ray scanner could revolutionize cancer surgery, pathology, drug inspection

Study reports on the immunogenicity of single-shot COVID-19 vaccine against SARS-CoV-2 variants

Cysteine persulfide found to be a new culprit in antibacterial resistance

Nose-to-brain: Nasal delivery of biopharmaceuticals to the brain

Trained dogs can accurately identify COVID-19 by scent

Review of COVID-19's long-term effects

Warmer conditions are not enough to prevent COVID-19 transmission, research shows

Study: COVID-19 vaccines safe for IBD patients

Research clarifies neuron-specific DNA methylation changes and characteristics in bipolar disorder

FDA releases draft guidance on measuring patient-reported outcomes in cancer clinical trials

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