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Genentech submits vemurafenib NDA for BRAF V600 mutation-positive metastatic melanoma

Genentech, a member of the Roche Group, today announced that the company submitted a New Drug Application for vemurafenib to the U.S. Food and Drug Administration for people with BRAF V600 mutation-positive metastatic melanoma, and that Roche submitted a Marketing Authorization Application to the European Medicines Agency for vemurafenib in the same indication.

11 May 2011

Novel ultrasound-targeted microbubble-destruction technology advances cure for prostate cancer

Cancer researchers are a step closer to finding a cure for advanced prostate cancer after effectively combining an anti-cancer drug with a viral gene therapy in vivo using novel ultrasound-targeted microbubble-destruction (UTMD) technology.

11 May 2011

GenoLogics enhances LIMS software for next-generation genomics labs

GenoLogics, a leading provider of laboratory information management system (LIMS) software for next-generation genomics labs, today announced a detailed product roadmap for its eponymous LIMS, designed to provide the scalability, adaptability and usability features necessary for mainstream adoption of the most advanced sequencing technologies while supporting existing genotyping platforms.

11 May 2011

Plexxikon seeks vemurafenib marketing approval from FDA and EMA for melanoma treatment

Plexxikon Inc., a member of the Daiichi Sankyo Group, today announced that applications for market approval for vemurafenib for the treatment of metastatic melanoma have been submitted to the U.S. Food and Drug Administration and the European Medicines Agency.

11 May 2011

Zebrafish research identifies undiscovered high-risk genetic features in T-cell acute lymphocytic leukemia

Leukemia is the most common childhood cancer; it also occurs in adults. Now researchers working with zebrafish at Huntsman Cancer Institute (HCI) at the University of Utah have identified previously undiscovered high-risk genetic features in T-cell acute lymphocytic leukemia (T-ALL), according to an article published online May 9, 2011, in the cancer research journal Oncogene.

11 May 2011

Second subject enrolled in human embryonic stem cell therapy trial for subacute thoracic spinal cord injury

Researchers at Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine and The Rehabilitation Institute of Chicago (RIC) recently enrolled their first subject in a national clinical research trial of a human embryonic stem cell-based therapy for participants with a subacute thoracic spinal cord injury.

11 May 2011

Protein critical to formation of new blood vessels could lead to therapies to starve cancerous tumors

UT Southwestern Medical Center researchers have discovered a protein that guides blood vessel development and eventually might lead to a treatment to keep cancer cells from spreading.

11 May 2011

Scientists unravel how genetic defects can help predict risk of sudden cardiac death

Sudden cardiac death is always a shocking, tragic event, especially when it occurs at a young age. But, for the first time, scientists are unraveling how genetic defects can help predict the risk of dying suddenly in individuals with one of the leading causes of this unfortunate phenomenon.

11 May 2011

Long non-coding RNA promotes melanoma cell survival and invasion

Traditionally, RNA was mostly known as the messenger molecule that carries protein-making instructions from a cell's nucleus to the cytoplasm. But scientists now estimate that approximately 97 percent of human RNA doesn't actually code for proteins at all. A flurry of research in the past decade has revealed that some types of non-coding RNAs switch genes on and off and influence protein function.

11 May 2011

UCLA researchers amp up power of killer CD8 T-cells to fight melanoma

Researchers with UCLA's Jonsson Comprehensive Cancer Center have discovered a way to amp up the power of killer T-cells, called CD8 cells, making them more functional for longer periods of time and boosting their ability to multiply and expand within the body to fight melanoma, a new study has found.

11 May 2011

MTTI obtains exclusive license for novel fluorescence dyes from Massachusetts General Hospital

Molecular Targeting Technologies, Inc., announced that it has obtained an exclusive license from the Massachusetts General Hospital for novel fluorescence dyes developed by Scott Hilderbrand, Ph.D. Fangwei Shao, Ph.D., and Ralph Weissleder, Ph.D. M.D.

11 May 2011

Allos, Mundipharma enter strategic collaboration to co-develop FOLOTYN

Allos Therapeutics, Inc. and Mundipharma International Corporation Limited today jointly announced that the companies have entered into a strategic collaboration agreement to co-develop FOLOTYN (pralatrexate injection).

11 May 2011

Micromet first quarter total revenues decrease to $5.5 million

Micromet, Inc., a biopharmaceutical company focused on the development and commercialization of next-generation antibodies for the treatment of cancer, today announced its financial results for the first quarter ended March 31, 2011.

10 May 2011

New study finds nitric oxide gas appears to affect source of sickle cell pain crises

Nitric oxide gas appears to directly impact the source of the classic, disabling pain crises of sickle cell disease, Georgia Health Sciences University researchers report.

10 May 2011

Researchers identify mitochondrial proteins that can affect human ageing

Mitochondria are the body's energy producers, the power stations inside our cells. Researchers at the University of Gothenburg, Sweden, have now identified a group of mitochondrial proteins, the absence of which allows other protein groups to stabilise the genome. This could delay the onset of age-related diseases and increase lifespan.

10 May 2011

Study confirms LcS-fermented milk reduces fever linked with acute norovirus gastroenteritis

The Laboratory Department for Probiotics Research at the Juntendo University Graduate School of Medicine studied supplementation of probiotic fermented milk containing Lactobacillus casei strain Shirota in elderly individuals living at a nursing home and confirmed reduced fever associated with acute norovirus gastroenteritis.

10 May 2011

Geron comments on recent European telomerase peptide cancer vaccine patents

Geron Corporation today commented on a ruling from the European Patent Office with regard to its European patent 084139, and the issuance of a second Geron patent covering telomerase peptides, EP1783139.

10 May 2011

Scientists decipher how hair stem cells can communicate with each other

In one of the first studies to look at the population behavior of a large pool of stem cells in thousands of hair follicles - as opposed to the stem cell of a single hair follicle - Keck School of Medicine of USC scientists deciphered how hair stem cells in mice and rabbits can communicate with each other and encourage mutually coordinated regeneration, according to an article published in the April 29 edition of the journal Science.

10 May 2011

UH chemist receives prestigious Sloan award for next-generation computer memory

Investigating the building blocks for next-generation computer memory has earned a University of Houston chemist his third Tier One research award.

10 May 2011

Mary Ann Liebert's peer-reviewed journal highlights latest developments in ocular gene therapy

Disorders of the eye are excellent targets for gene therapy because the ocular environment is readily accessible, relatively easy to monitor, and sequestered from the rest of the body.

10 May 2011

Cell News and Research

Genentech submits vemurafenib NDA for BRAF V600 mutation-positive metastatic melanoma

Novel ultrasound-targeted microbubble-destruction technology advances cure for prostate cancer

GenoLogics enhances LIMS software for next-generation genomics labs

Plexxikon seeks vemurafenib marketing approval from FDA and EMA for melanoma treatment

Zebrafish research identifies undiscovered high-risk genetic features in T-cell acute lymphocytic leukemia

Second subject enrolled in human embryonic stem cell therapy trial for subacute thoracic spinal cord injury

Protein critical to formation of new blood vessels could lead to therapies to starve cancerous tumors

Scientists unravel how genetic defects can help predict risk of sudden cardiac death

Long non-coding RNA promotes melanoma cell survival and invasion

UCLA researchers amp up power of killer CD8 T-cells to fight melanoma

MTTI obtains exclusive license for novel fluorescence dyes from Massachusetts General Hospital

Allos, Mundipharma enter strategic collaboration to co-develop FOLOTYN

Micromet first quarter total revenues decrease to $5.5 million

New study finds nitric oxide gas appears to affect source of sickle cell pain crises

Researchers identify mitochondrial proteins that can affect human ageing

Study confirms LcS-fermented milk reduces fever linked with acute norovirus gastroenteritis

Geron comments on recent European telomerase peptide cancer vaccine patents

Scientists decipher how hair stem cells can communicate with each other

UH chemist receives prestigious Sloan award for next-generation computer memory

Mary Ann Liebert's peer-reviewed journal highlights latest developments in ocular gene therapy

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