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DFG approves establishment of new CRCs; research topics range from modern prostheses to political reforms to marine bacteria

The DFG has approved the establishment of 17 new Collaborative Research Centres as of 1 January 2010. This decision was made recently by the relevant Grants Committee in Bonn.

1 Dec 2009

Portuguese scientists identify a molecular mechanism that can lead to metastases in breast cancers

Portuguese scientists identified a molecular mechanism that can lead to metastases (spread of the cancer from the original site to other remote parts of the body) in breast cancers. Abnormally high levels of P-cadherin - an adhesion molecule that enables cells to bind together - occur in about a third of all breast cancers and are associated with poor prognosis.

1 Dec 2009

Amgen to present updated data on Nplate at the 2009 ASH meeting

Amgen Inc. today announced that it will present updated long-term safety and efficacy data for Nplate® (romiplostim) in adult chronic immune (idiopathic) thrombocytopenic purpura (ITP). Additionally, Amgen will present the first Nplate study in a pediatric setting as well as in patients with myelodysplastic syndromes (MDS) at the 2009 American Society of Hematology (ASH) Annual Meeting and Exposition (Dec. 5 - 8, 2009).

1 Dec 2009

Comprehensive investigation employing FRET to study amino acid transporter GAT1 reported

In the December 2009 issue of the Journal of General Physiology (www.jgp.org), Moss et al. report a comprehensive investigation employing F-rster resonance energy transfer (FRET) to study the {gamma}-amino acid (GABA) transporter GAT1, a member of the family that includes transporters for neurotransmitters dopamine (DAT), serotonin (SERT), norepinephrine (NET) and glycine (GlyT).

1 Dec 2009

Translational Medicine Graduate Training Program awarded $700,000 HHMI grant

The Graduate Training Program in Translational Medicine at the University of North Carolina at Chapel Hill has been awarded a four-year, $700,000 "Med into Grad" renewal grant from the Howard Hughes Medical Institute.

1 Dec 2009

Researchers devise a way to deliver right therapy directly to tumors using aptamers

Finding and treating a tumor without disturbing normal tissue presents challenges - sometimes the most effective therapies can be invasive and harsh.

1 Dec 2009

High-frequency ultrasound with elastography improves skin cancer diagnosis

High-frequency ultrasound with elastography can help differentiate between cancerous and benign skin conditions, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

1 Dec 2009

Intelliject announces an exclusive license with sanofi-aventis for epinephrine auto-injector

Intelliject, Inc. today announced an exclusive license with sanofi-aventis U.S. for a novel epinephrine auto-injector, in the U.S. and Canada territory. Under the license, sanofi-aventis U.S. shall be responsible for manufacturing and commercialization.

1 Dec 2009

University of Navarra Hospital launches clinical trials to assess the efficacy of immunotherapy treatment

The University of Navarra Hospital has launched a series of clinical trials in order to assess the efficacy of an immunotherapy treatment. This approach involves the application of personalised vaccines -produced from healthy and tumour cells from the patient him or herself- and designed to combat glioblastomas, one of the most aggressive and frequent malignant tumours.

1 Dec 2009

ChemGenex Pharmaceuticals to present updated clinical data from its clinical trials with Omapro

ChemGenex Pharmaceuticals Limited announced today that updated clinical data from several of its clinical trials with Omapro™ (omacetaxine mepesuccinate) will be presented at the upcoming 51st American Society of Hematology Annual Meeting in New Orleans, Louisiana.

1 Dec 2009

Phase 1 study of preventive HIV vaccine testing a novel delivery mechanism completed

A Phase 1 study of a preventive HIV vaccine testing a novel delivery mechanism known as electroporation – the use of electrical pulses to increase the immune responses elicited by DNA vaccines – was recently completed in New York City.

1 Dec 2009

New research shows people who feel lonely spread that feeling to others

Loneliness, like a bad cold, can spread among groups of people, research at the University of Chicago, the University of California-San Diego and Harvard shows.

1 Dec 2009

Drinking sugar-sweetened cola a week prior to pregnancy elevates diabetes during pregnancy

Researchers from LSU Health Sciences Center New Orleans School of Public Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Harvard School of Public Health, Brigham and Women's Hospital, and Harvard Medical School, have found for the first time that drinking more than 5 servings of sugar- sweetened cola a week prior to pregnancy appears to significantly elevate the risk of developing diabetes during pregnancy.

1 Dec 2009

Phi Health launches high-performance MRI system at RSNA 2009

Phi Health, a healthcare technology company, announced at the RSNA 2009 Annual Meeting in Chicago, IL, November 29, 2009 – December 4, 2009, that it is introducing Memex, a proprietary high-performance, yet low-cost 1.5T MRI system.

1 Dec 2009

Neurotoxic heavy metal can slow the progression of Lou Gehrig's disease

New discoveries have been made about how an elevated level of lead, which is a neurotoxic heavy metal, can slow the progression of amyotrophic lateral sclerosis, or Lou Gehrig's disease - findings that could point the way to a new type of therapy.

1 Dec 2009

Reductionist model provides new insights on HIV infection

A major obstacle to HIV research is the virus's exquisite specialisation for its human host - meaning that scientists' traditional tools, like the humble lab mouse, can deliver only limited information. Now, a team of researchers writing in BioMed Central's open access Journal of Biology have made an ingenious assault on this problem by creating a mouse that has key features of HIV infection without being infected with HIV.

1 Dec 2009

Clinical trials of personalised vaccines to fight glioblastomas

The University of Navarra Hospital has launched a series of clinical trials in order to assess the efficacy of an immunotherapy treatment. This approach involves the application of personalised vaccines —produced from healthy and tumour cells from the patient him or herself— and designed to combat glioblastomas, one of the most aggressive and frequent malignant tumours.

30 Nov 2009

Tripep completes phase I clinical study of its ChronVac-C hepatitis C virus DNA vaccine

Inovio Biomedical Corporation, a leader in DNA vaccine design, development and delivery, announced today that its partner Tripep AB of Sweden has completed its phase I clinical study of its ChronVac-C hepatitis C virus DNA vaccine delivered using Inovio’s electroporation technology.

30 Nov 2009

BioMarin Pharmaceutical receives FDA orphan drug designation for 3,4-DAP

BioMarin Pharmaceutical Inc. announced today that the Food and Drug Administration (FDA) has granted orphan drug designation for 3,4-diaminopyridine (3,4-DAP), amifampridine phosphate, for the rare autoimmune disease Lambert Eaton Myasthenic Syndrome (LEMS). 3,4-DAP has previously received orphan drug designation in the E.U.

30 Nov 2009

NOVAVAX completes patient enrollment in its trivalent seasonal influenza VLP vaccine Phase II study

Novavax, Inc. announced today it has completed enrollment in the Phase II clinical study of its trivalent seasonal influenza (2008/2009 recommended strains) VLP vaccine candidate in healthy adults 60 years of age or older (older adults). This randomized, double-blind, active-controlled study is comparing the safety, tolerability and immunogenicity of two different doses (15 mcg and 60 mcg) of Novavax's trivalent seasonal influenza VLP vaccine to a commercially available trivalent inactivated vaccine, TIV (Fluzone®).

30 Nov 2009

Cell News and Research

DFG approves establishment of new CRCs; research topics range from modern prostheses to political reforms to marine bacteria

Portuguese scientists identify a molecular mechanism that can lead to metastases in breast cancers

Amgen to present updated data on Nplate at the 2009 ASH meeting

Comprehensive investigation employing FRET to study amino acid transporter GAT1 reported

Translational Medicine Graduate Training Program awarded $700,000 HHMI grant

Researchers devise a way to deliver right therapy directly to tumors using aptamers

High-frequency ultrasound with elastography improves skin cancer diagnosis

Intelliject announces an exclusive license with sanofi-aventis for epinephrine auto-injector

University of Navarra Hospital launches clinical trials to assess the efficacy of immunotherapy treatment

ChemGenex Pharmaceuticals to present updated clinical data from its clinical trials with Omapro

Phase 1 study of preventive HIV vaccine testing a novel delivery mechanism completed

New research shows people who feel lonely spread that feeling to others

Drinking sugar-sweetened cola a week prior to pregnancy elevates diabetes during pregnancy

Phi Health launches high-performance MRI system at RSNA 2009

Neurotoxic heavy metal can slow the progression of Lou Gehrig's disease

Reductionist model provides new insights on HIV infection

Clinical trials of personalised vaccines to fight glioblastomas

Tripep completes phase I clinical study of its ChronVac-C hepatitis C virus DNA vaccine

BioMarin Pharmaceutical receives FDA orphan drug designation for 3,4-DAP

NOVAVAX completes patient enrollment in its trivalent seasonal influenza VLP vaccine Phase II study

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