Immune Response News and Research

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Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research from The University of Texas MD Anderson Cancer Center.

22 Feb 2020

New Endothelial Cell Atlas can be used to improve treatments for many diseases

New surprising knowledge on endothelial cells in a dozen different murine tissues is now available in an open access, user-friendly, database for professionals.

20 Feb 2020

Researchers identify a protein that aids in colorectal cancer metastasis

A protein that helps colorectal cancer cells spread to other parts of the body could be an effective treatment target.

20 Feb 2020

Vaccine for COVID-19 coronavirus could soon be a reality

A team of researchers from the University of Texas at Austin and the National Institutes of Health have managed to make significant progress in the development of a vaccine against the fast-spreading and virulent COVID-19/Novel coronavirus that started in Wuhan, Hubei province of China in December 2019 and is still infecting thousands.

19 Feb 2020

How malaria evades the body’s immune response

Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes. In 2018, there were over 200 million cases of malaria worldwide. Now, a team of researchers found evidence that the malaria parasite can detect a molecule released by approaching immune cells, using it to protect itself and evade the attack by the body’s immune system.

19 Feb 2020

Potential method for better treatment of premature babies

A new study published in the journal Immunology in February 2020 reports the discovery of a process that occurs in the body naturally, but which enhances the production of type 3 innate lymphoid cells (ILCs) in the lung alveoli of premature babies. These are sentinel cells that keep the mucosal surfaces clean and healthy. They are crucial to building resistance to infection within the human body.

18 Feb 2020

Scientists use toxin from rattlesnake venom for chronic pain

Rattlesnake (Crotalus adamanteus) is the largest venomous snake in North America, reaching 8 feet and weighing up to 10 pounds. In the past, medical experts believe that the toxin in rattlesnake venom, crotoxin, is a promising compound for the treatment of chronic pain.

18 Feb 2020

Plant-based diets improve heart health via the gut microbiome

A new study published in February 2020 in the Journal of the American College of Cardiology reports that a reduced intake of animal-based foods and a diet based on plants can result in a lower risk of coronary heart disease (CHD) by influencing the gut microbiome pattern to favor beneficial species.

17 Feb 2020

Immune system may target other remote areas of the brain to improve stroke recovery

New University of Kentucky research shows that the immune system may target other remote areas of the brain to improve recovery after a stroke.

17 Feb 2020

Simple blood test measures the body's immune response to improve ovarian cancer diagnosis

Researchers have developed a simple blood test that measures the body's own immune response to improve diagnosis of ovarian cancer.

17 Feb 2020

Novel formulation allows use of toxin from rattlesnake venom to control neuropathic pain

Crotoxin, extracted from the venom of the South American rattlesnake Crotalus durissus terrificus, has been studied for almost a century for its analgesic, anti-inflammatory and antitumor activities and as an even more powerful muscle paralyzer than botulinum toxin.

16 Feb 2020

Research reveals new pathogenic mechanism for influenza NS1 protein

Influenza is a deadly virus, with about 290,000 to 650,000 deaths worldwide each year. When pandemics hit, the toll can soar: The Spanish flu of 1918 caused 40 million to 50 million deaths, the Asian flu of 1957 caused 2 million deaths, and the Hong Kong flu of 1968 caused 1 million deaths.

16 Feb 2020

Immune cells count each other in order to decide whether to attack

A new study published in the journal Nature Communications in February 2020 shows that immune cells consult and coordinate with each other at the site of activity to bring about a balanced but adequate reaction and stave off the threat.

13 Feb 2020

Acid reflux drug may be a promising therapy to reduce preterm birth

Lansoprazole, an over-the-counter acid reflux drug that is often taken by pregnant women, may be a promising therapy to reduce preterm birth, according to a computational drug repurposing study that also tested several of the drugs in mice.

13 Feb 2020

Macrophages consult with neighbors before making decisions

Many people consult their friends and neighbors before making a big decision. It turns out that cells also are consulting their neighbors in the human body.

13 Feb 2020

Yale scientists enlist most unlikely ally in efforts to treat glioblastoma

Glioblastomas are relentless, hard-to-treat, and often lethal brain tumors. Yale scientists have enlisted a most unlikely ally in efforts to treat this form of cancer -- elements of the Ebola virus.

12 Feb 2020

Researchers engineer probiotics to safely deliver immunotherapies to tumors

Researchers at Columbia Engineering have engineered probiotics to safely deliver immunotherapies within tumors.

12 Feb 2020

UChicago researchers develop first accurate mouse model of celiac disease

Researchers at the University of Chicago have developed the first truly accurate mouse model of celiac disease. The animals have the same genetic and immune system characteristics as humans who develop celiac after eating gluten. This provides a vital research tool for developing and testing new treatments for the disease.

12 Feb 2020

NETRF announces $3.5 million in research grants to improve neuroendocrine tumor treatment

The Neuroendocrine Tumor Research Foundation, Boston, MA, today announced $3.5 million in neuroendocrine tumor research grants to fund 12 projects around the world in pursuit of more precise treatments for this uncommon cancer affecting an estimated 171,000 Americans.

12 Feb 2020

Individual response to Ebola predicted by new method

The Ebola virus produces widely varying reactions, from asymptomatic illness to death, in people depending on the individual's susceptibility. But what drives this difference in response? A new study published in the journal Cell Reports on February 2020 goes one step further in understanding how the immune system reacts to the virus causing varying levels of severity of disease between cases.

11 Feb 2020