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Sorafenib, sunitinib provide no benefit to patients with locally advanced kidney cancer

Findings from a federally funded study suggest that patients with locally advanced kidney cancer should not be treated with either adjuvant (post-surgery) sorafenib or sunitinib. The average period to disease recurrence was similar between those who received sorafenib or sunitinib after surgery (5.6 years) and those treated with placebo (5.7 years).

25 Feb 2015

Researchers develop revolutionary approach to treat drug-resistant tumors

In greater than 90 percent of cases in which treatment for metastatic cancer fails, the reason is that the cancer is resistant to the drugs being used. To treat drug-resistant tumors, doctors typically use multiple drugs simultaneously, a practice called combination therapy.

25 Feb 2015

Study: Gene variant linked to increased risk of vincristine-induced peripheral neuropathy in children

Children with acute lymphoblastic leukemia who had a certain gene variant experienced a higher incidence and severity of peripheral neuropathy after receiving treatment with the cancer drug vincristine, according to a study in the February 24 issue of JAMA.

25 Feb 2015

Direct brain responsive neurostimulator reduces seizures, improves quality of life

Piotr Olejniczak, MD, PhD, LSU Health New Orleans Professor of Neurology and Director of the Epilepsy Center, contributed to a study of the long-term effectiveness of the first direct brain responsive neurostimulator for partial onset, or focal, seizures that cannot be controlled with medication.

25 Feb 2015

Researchers find that new targeted drugs can attack weak spots in cancer cells

Scientists have identified weak spots in cancer cells that could be targeted and attacked by new precision drugs.

25 Feb 2015

Discovery demonstrates effect of exercise to prevent chronic health conditions

A researcher at the University of Virginia School of Medicine has magnified a benefit of exercise in mice to provide a "profound" protection from diabetic cardiomyopathy, a potentially deadly heart condition that affects many people with diabetes. The discovery demonstrates the power of exercise to prevent chronic health conditions and suggests that one day some benefits of exercise may come in a pill or bottle.

25 Feb 2015

Investigators define prevalence, associated factors for vasospasm in children with brain injuries

Vasospasm, or severe narrowing of blood vessels, is a dangerous complication observed in children with moderate to severe traumatic brain injury. In a paper recently published in Critical Care Medicine, investigators at Nationwide Children's Hospital have further defined the prevalence, associated factors and time course for vasospasm in children with these brain injuries.

25 Feb 2015

Reslizumab drug appears to reduce risk of severe asthma attacks

An investigational drug appears to cut the risk of severe asthma attacks in half for patients who have difficulty controlling the disorder with standard medications, according to results from two multicenter clinical trials.

25 Feb 2015

Hormone therapy safe for transgender individuals, say BUSM researchers

In the most comprehensive review to date addressing the relative safety of hormone therapy for transgender persons, researchers from Boston University School of Medicine have found that hormone therapy in transgender adults is safe. The findings, which appear in the Journal of Clinical and Translational Endocrinology, may help reduce the barriers for transgender individuals to receive medical care.

25 Feb 2015

Patients battling sleep apnea find relief from Zzoma device

Thousands of patients in the U.S. and Europe battling positional obstructive sleep apnea (OSA) are finding relief from Zzoma, an FDA-cleared medical device designed by physicians at Sleep Specialists, LLC.

25 Feb 2015

PCORI funds five patient-centered comparative effectiveness research studies

The Patient-Centered Outcomes Research Institute Board of Governors today approved awards totaling more than $64 million to fund five large patient-centered comparative effectiveness research (CER) studies that will answer critical clinical questions about care for cancer, back pain, and stroke.

25 Feb 2015

Serous ovarian cancer is more deadly, shows Cancer Research UK study

THE most common type of ovarian cancer is more deadly if it consists of a patchwork of different groups of cells, according to a Cancer Research UK study published today (Tuesday) in PLOS Medicine.

25 Feb 2015

Hair sample tests reveal underreported exposure to tobacco smoke among preemies with lung disease

Public health experts have long known that tobacco smoke exposure (TSE) can be harmful for children with bronchopulmonary dysplasia, a lung disease that often accompanies premature birth.

24 Feb 2015

Eight professional health organizations call for action to reduce firearms injuries, deaths in the U.S.

Leaders from eight professional health organizations, including the American College of Emergency Physicians, and the American Bar Association have issued a call to action to reduce firearms injuries and deaths in the United States.

24 Feb 2015

Agena releases MassARRAY 24-Well System for mass spectrometry-based genetic testing

Agena Bioscience today released the MassARRAY 24-Well System for mass spectrometry-based genetic analysis, adding to its existing MassARRAY portfolio. The new 24-well format is tailored to smaller clinical testing laboratories requiring modest sample throughput, reduced initial hardware costs, and reduced time to result.

24 Feb 2015

MPP, MSD sign licensing agreement for paediatric formulations of raltegravir

The Medicines Patent Pool announced a licence today with MSD, known as Merck in the United States and Canada, for paediatric formulations of raltegravir, a key medicine approved for children living with HIV four weeks of age and older.

24 Feb 2015

Epigenetics and women’s health research: an interview with Professor Steve Conlan, Swansea University

Our research into gynaecological oncology focuses around understanding mechanisms of how genes are regulated or how they become dysregulated in a disease; and also the effects that has on the surface of the endometrium and also the function of the ovaries...

From Chromatrap® - Porvair Sciences Ltd 24 Feb 2015

Diets high in animal proteins can worsen progression of kidney disease

An estimated 26 million people in the United States have chronic kidney disease, which can lead to complete kidney failure. Once the kidneys fail, patients either need to undergo dialysis treatments three times a week or have a kidney transplant to remain alive.

24 Feb 2015

People who exhibit resistance to aspirin may be at risk of more severe strokes

People who exhibit a resistance to aspirin may be more likely to have more severe strokes than people who still respond to the drug, according to a study released today that will be presented at the American Academy of Neurology's 67th Annual Meeting in Washington, DC, April 18 to 25, 2015.

24 Feb 2015

Study reveals how household net worth affects breast cancer care

Household net worth is a major and overlooked factor in adherence to hormonal therapy among breast cancer patients and partially explains racial disparities in quality of care. The findings suggest that physicians, health insurers, and policy makers need to pay more attention to this economic variable to ensure that breast cancer patients receive this potentially life-saving treatment.

24 Feb 2015

Medicine News and Research

Sorafenib, sunitinib provide no benefit to patients with locally advanced kidney cancer

Researchers develop revolutionary approach to treat drug-resistant tumors

Study: Gene variant linked to increased risk of vincristine-induced peripheral neuropathy in children

Direct brain responsive neurostimulator reduces seizures, improves quality of life

Researchers find that new targeted drugs can attack weak spots in cancer cells

Discovery demonstrates effect of exercise to prevent chronic health conditions

Investigators define prevalence, associated factors for vasospasm in children with brain injuries

Reslizumab drug appears to reduce risk of severe asthma attacks

Hormone therapy safe for transgender individuals, say BUSM researchers

Patients battling sleep apnea find relief from Zzoma device

PCORI funds five patient-centered comparative effectiveness research studies

Serous ovarian cancer is more deadly, shows Cancer Research UK study

Hair sample tests reveal underreported exposure to tobacco smoke among preemies with lung disease

Eight professional health organizations call for action to reduce firearms injuries, deaths in the U.S.

Agena releases MassARRAY 24-Well System for mass spectrometry-based genetic testing

MPP, MSD sign licensing agreement for paediatric formulations of raltegravir

Epigenetics and women’s health research: an interview with Professor Steve Conlan, Swansea University

Diets high in animal proteins can worsen progression of kidney disease

People who exhibit resistance to aspirin may be at risk of more severe strokes

Study reveals how household net worth affects breast cancer care

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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