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African AIDS drug trial stopped prematurely

One of the studies in three African countries where women were given an AIDS drug to prevent HIV infection is being stopped because the project is not working, researchers said Monday. These women on the trial were taking a daily dose of the drug Truvada or a look-alike placebo pill and had an equal chance of becoming infected. The ones taking Truvada were expected to have had a much lower infection rate.

19 Apr 2011

Gene mutation in Tibetian Terrier dogs causes hereditary form of Parkinson's disease in humans

University of Missouri researchers believe both man and animal will benefit from their discovery that the same gene mutation found in Tibetan Terrier dogs can also be found in a fatal human neurological disorder related to Parkinson's disease.

19 Apr 2011

Pupil measurements can predict patients' response to cognitive therapy

The scientific foundation of psychiatry is growing rapidly, yet it is a branch of medicine distinctive for the relative absence of biological tests in routine clinical practice.

19 Apr 2011

Cumberland acquires Vanderbilt's ifetroban rights

Cumberland Pharmaceuticals Inc., a specialty pharmaceutical company focused on hospital acute care and gastroenterology markets, today announced that it has entered into an agreement to acquire the rights to ifetroban, a new Phase II development product.

19 Apr 2011

Positive interim anemia response data from YM's CYT387 Phase I/II trial in myelofibrosis

YM BioSciences Inc., today announced that updated interim anemia response data were reported for the first 60 patients enrolled in the Phase I/II trial of its JAK1/JAK2 inhibitor, CYT387, for the treatment of myelofibrosis.

19 Apr 2011

Circassia closes $98 million fundraising for lead allergy programmes

Circassia Ltd, a specialty biopharmaceutical company focused on allergy, today announced that it has closed a GBP60 million fundraising. The funding round was led by Imperial Innovations, and included investments from other existing shareholders, including Invesco Perpetual.

19 Apr 2011

AADSM event to discuss latest advances in sleep-disordered breathing research

Nearly 800 dental sleep medicine professionals from around the world will gather at the 20th Anniversary Meeting of the American Academy of Dental Sleep Medicine, which will take place Saturday, June 11, 2011, at the Hilton Minneapolis in Minneapolis, Minn.

19 Apr 2011

Seattle enters second ADC research collaboration agreement with Genmab

Genmab A/S and Seattle Genetics, Inc. announced today that the companies have entered into a second antibody-drug conjugate research collaboration agreement.

19 Apr 2011

Exacerbate-reverse' approach can identify potential therapy for fatal childhood disease

Many genes that cause human diseases have parallel genes in other organisms, including yeast. Now Columbia University researchers have used an innovative yeast-based screening method to identify a possible treatment for the fatal childhood disease Niemann-Pick C.

19 Apr 2011

National Institute on Aging/Alzheimer's Association update new dementia guidelines

For the first time in 27 years, clinical diagnostic criteria for Alzheimer's disease dementia have been revised, and research guidelines for earlier stages of the disease have been characterized to reflect a deeper understanding of the disorder.

19 Apr 2011

BioSante, Aduro BioTech enter license agreement for GVAX cancer vaccines

Aduro BioTech, a clinical-stage immunotherapy company, has licensed GVAX Pancreas Cancer Vaccine and GVAX Prostate Cancer Vaccine BioSante Pharmaceuticals, Inc. in exchange for milestone and royalty payments after commercialization.

19 Apr 2011

FDA approval of Pipeline Embolization Device offers better options for treatment of large/giant aneurysms

The recent U.S. Food and Drug Administration (FDA) approval of a brain aneurysm device has opened the door for neurosurgeons at Jefferson Hospital for Neuroscience (JHN) to offer advanced treatment to patients suffering from large or giant aneurysms who otherwise have limited, effective options.

19 Apr 2011

BioSante licenses Pancreas and Prostate cancer vaccines to Aduro BioTech

BioSante Pharmaceuticals, Inc. today announced it has licensed its Pancreas Cancer Vaccine and Prostate Cancer Vaccine to Aduro BioTech, a clinical-stage immunotherapy company, solely for use in combination with Aduro's proprietary vaccine platform based on Listeria monocytogenes (Lm).

19 Apr 2011

Journal of Clinical Oncology publishes CytRx tamibarotene Phase 2b trial results in APL

CytRx Corporation, a biopharmaceutical company specializing in oncology, today announced the publication of a case report in the peer-reviewed Journal of Clinical Oncology documenting the use of tamibarotene in the successful treatment of a patient with recurrent advanced-stage acute promyelocytic leukemia.

19 Apr 2011

Bedford Labs launches cancer drug Topotecan Hydrochloride for Injection

Bedford Laboratories, a division of Ben Venue Laboratories, Inc., is pleased to announce the addition of Topotecan Hydrochloride for Injection, 4 mg (base)/vial to its diverse portfolio. Topotecan is AP Bioequivalent to the reference listed drug Hycamtin® (topotecan HCl) for injection by GlaxoSmithKline.

19 Apr 2011

Nerve disorder expert Jack Griffin passes away

Jack Griffin, an internationally acclaimed and admired expert on diseases of the peripheral nervous system, founding director of the Johns Hopkins Brain Science Institute, and former director of Hopkins School of Medicine's Department of Neurology, died Saturday, April 16, after a long battle with bladder cancer. He was 69.

18 Apr 2011

Japan Tobacco and Torii commence ferric citrate Phase 3 clinical program for hyperphosphatemia

Keryx Biopharmaceuticals, Inc., announced today that its Japanese partner, Japan Tobacco Inc. (JT) and Torii Pharmaceutical Co., Ltd., JT's pharmaceutical business subsidiary, has commenced the Phase 3 clinical program of ferric citrate in Japan for the treatment of patients with hyperphosphatemia.

18 Apr 2011

Tweaking gene in satellite cells may increase lifespan of people with muscular dystrophy

Researchers have long questioned why patients with Duchenne muscular dystrophy (DMD) tend to manage well through childhood and adolescence, yet succumb to their disease in early adulthood, or why elderly people who lose muscle strength following bed rest find it difficult or impossible to regain.

18 Apr 2011

Pharma Tech expands agreement for Shasta Genstrip

InstaCare Corp. a leading provider of prescription diagnostics, home testing products for the chronically ill, a leading fulfillment provider of direct to patient diabetes programs, and a leading developer of revolutionary cell phone centric e-health products and technologies, today announced that its operating subsidiary, Pharma Tech Solutions, Inc., has significantly expanded its agreement to control, manage and distribute the novel at-home diagnostic product, the Shasta Genstrip.

18 Apr 2011

Scientists identify networks of genes critical in embryonic-heart development

Scientists at the Gladstone Institutes have identified networks of genes that play an important role in embryonic-heart development, advancing knowledge of how healthy hearts develop-and offering clues about how to combat a common birth defect known as congenital heart disease.

18 Apr 2011

Cell News and Research

African AIDS drug trial stopped prematurely

Gene mutation in Tibetian Terrier dogs causes hereditary form of Parkinson's disease in humans

Pupil measurements can predict patients' response to cognitive therapy

Cumberland acquires Vanderbilt's ifetroban rights

Positive interim anemia response data from YM's CYT387 Phase I/II trial in myelofibrosis

Circassia closes $98 million fundraising for lead allergy programmes

AADSM event to discuss latest advances in sleep-disordered breathing research

Seattle enters second ADC research collaboration agreement with Genmab

Exacerbate-reverse' approach can identify potential therapy for fatal childhood disease

National Institute on Aging/Alzheimer's Association update new dementia guidelines

BioSante, Aduro BioTech enter license agreement for GVAX cancer vaccines

FDA approval of Pipeline Embolization Device offers better options for treatment of large/giant aneurysms

BioSante licenses Pancreas and Prostate cancer vaccines to Aduro BioTech

Journal of Clinical Oncology publishes CytRx tamibarotene Phase 2b trial results in APL

Bedford Labs launches cancer drug Topotecan Hydrochloride for Injection

Nerve disorder expert Jack Griffin passes away

Japan Tobacco and Torii commence ferric citrate Phase 3 clinical program for hyperphosphatemia

Tweaking gene in satellite cells may increase lifespan of people with muscular dystrophy

Pharma Tech expands agreement for Shasta Genstrip

Scientists identify networks of genes critical in embryonic-heart development

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