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Discovery offers much needed information about how virulent insect-borne diseases cause infection

For decades, scientists have thought the bacteria that cause the bubonic plague hijack host cells at the site of a fleabite and are then taken to the lymph nodes, where the bacteria multiply and trigger severe disease. But UNC School of Medicine researchers discovered that this accepted theory is off base. The bacteria do not use host cells; they traffic to lymph nodes on their own and not in great numbers.

16 Feb 2015

Hospira announces launch of first biosimilar monoclonal antibody in Europe

Hospira, Inc., a world leader in the development of biosimilar therapies, today announced the launch of the first biosimilar monoclonal antibody (mAb), Inflectra (infliximab), in major European markets.

16 Feb 2015

Researchers demonstrate advantages of implanted defibrillator in preventing non-ischaemic heart failure

Sudden cardiac arrest is a possible cause of death in patients with non-ischaemic cardiac muscle weakness, i.e. a type of heart failure caused by genetics or for which no cause is known. Now, researchers at the University Department of Internal Medicine II at the MedUni Vienna (Clinical Department of Cardiology), as part of an international cooperation, have successfully demonstrated the advantages of an implanted defibrillator (ICD) as a means of prevention in patients with moderately restricted cardiac function, and that patients with the condition must be treated as carefully as patients with ischaemic heart failure which has developed following a heart attack, for example.

16 Feb 2015

NTU Singapore setting up new institute to find cures for human diseases

Nanyang Technological University is setting up a new institute to advance research in the life sciences, with a focus on ramping up Singapore's efforts in finding cures for human diseases.

16 Feb 2015

Researchers report first evidence of Seoul hantavirus in wild rats in the Netherlands

In a paper just published in the peer reviewed journal Infection, Ecology & Epidemiology, researchers report discovering the first evidence of Seoul hantavirus (SEOV) in the wild rat population in the Netherlands. The discovery comes on the heels of similar ones in France, Belgium and the United Kingdom in recent years, and has some researchers concerned about the potential spread of the virus to humans.

16 Feb 2015

Researchers discover molecular 'switch' that controls replication, transcription of mitochondria DNA

A team of researchers led by Dmitry Temiakov, PhD, of the Rowan University School of Osteopathic Medicine (RowanSOM), has discovered a molecular 'switch' that controls replication and transcription of mitochondria DNA, a key finding that could influence the development of targeted therapies for cancer, developmental processes related to fertility and aging.

16 Feb 2015

Widely used clinical calculators overrate heart attack risk

Most "risk calculators" used by clinicians to gauge a patient's chances of suffering a heart attack and guide treatment decisions appear to significantly overestimate the likelihood of a heart attack, according to results of a study by investigators at Johns Hopkins and other institutions.

16 Feb 2015

New laser technology shows promise for cancer treatment

Surgeons rely on 200-year-old technology when removing cancer--sight and touch--to determine how much to remove and what to leave alone. Laser technology pioneered at Florida Atlantic University has the promise to help a surgeon better determine if an area is cancer or healthy tissue. Moreover, when combined with laser treatment for cancer, this work lays the groundwork for laser robotic treatment of cancer.

16 Feb 2015

Breast density laws could pose risk of unnecessary procedures for women with breast cancer

Women with dense breast tissue are at increased risk of breast cancer. Dense breast tissue, generally defined as having more fibroglandular than fatty tissue, can make it more difficult for radiologists to detect cancer on screening mammography.

16 Feb 2015

New electronic model holds promise of revolutionizing shared decision-making in doctor's office

Traditional decision aids to help patient-doctor discussions have drawbacks, but a new electronic model developed by McMaster University researchers holds promise of revolutionizing shared decision-making in the doctor's office with the touch of an electronic tablet.

16 Feb 2015

New study indicates that cancer patients rarely push for unnecessary tests, treatments

Physicians often blame patient demands for contributing to high medical costs, however, a new study involving more than 5,000 patient-clinician visits indicates that cancer patients rarely push for unnecessary tests and treatments from their health care providers.

16 Feb 2015

Increasing opioid doses to manage chronic pain may intensify depression

Patients who increased doses of opioid medicines to manage chronic pain were more likely to experience an increase in depression, according to Saint Louis University findings in Pain.

16 Feb 2015

MJC ICM works out general guidelines for intensive care medicine

Frankfurt-based intensive care medical practitioner, Kai Zacharowski, is working on a joint curriculum for Europe.

16 Feb 2015

Techimmuna may help diagnose rheumatoid arthritis

NCBJ POLATOM Radioisotope Centre has just introduced a new product to the nuclear medicine preparations market. Techimmuna will help to diagnose various cases of inflammation, in particular rheumatoid arthritis.

16 Feb 2015

Adult survivors of childhood cancer at risk for pituitary hormone deficiencies

Decades after undergoing cranial irradiation for childhood cancer, St. Jude Children's Research Hospital investigators found that adult survivors of pediatric cancer remain at risk for pituitary hormone deficiencies that may diminish their health and quality of life.

16 Feb 2015

Short-term cognitive behavioral therapy reduces suicide attempts among at-risk soldiers

Short-term cognitive behavioral therapy dramatically reduces suicide attempts among at-risk military personnel, according to findings from a research study that included investigators from The University of Texas Health Science Center at San Antonio.

16 Feb 2015

R. Bryan Miller Symposium to spotlight special focus on rare disease research

The University of California, Davis Department of Chemistry will spotlight a special focus on rare disease research with this year's 15th annual R. Bryan Miller Symposium. Experts in rare diseases will gather at the UC Davis Conference Center March 5 for a conference highlighting the opportunities and challenges in applying cutting edge technologies and "precision medicine" to better treat conditions that together affect millions of people, especially children.

16 Feb 2015

Novartis receives priority review status from FDA for heart failure medicine LCZ696

Novartis announced today that the US Food and Drug Administration has granted priority review for LCZ696, an investigational medicine for the treatment of heart failure with reduced ejection fraction (HFrEF). The designation is intended to accelerate the review of therapies that offer a significant improvement in the safety or effectiveness of the treatment, prevention or diagnosis of a serious condition.

16 Feb 2015

Consortium formed to develop program to improve health outcomes for Ebola patients

Scripps Translational Science Institute will lead a consortium of four partners to develop a program through which wearable, wireless health sensors, a wireless vital signs monitoring platform and advanced analytics technology will be tested in a new "precision medicine" approach designed to improve health outcomes for Ebola patients, increase the safety of health care workers and reduce risk of spreading the virus to others.

16 Feb 2015

Researchers develop novel strategy in fight against cancer

A team of researchers led by Associate Professor Caroline Lee from the Yong Loo Lin School of Medicine at the National University of Singapore, in collaboration with Associate Professor Song Jianxing of the Department of Biological Sciences at the NUS Faculty of Science, has developed a novel strategy in the fight against cancer.

15 Feb 2015

Medicine News and Research

Discovery offers much needed information about how virulent insect-borne diseases cause infection

Hospira announces launch of first biosimilar monoclonal antibody in Europe

Researchers demonstrate advantages of implanted defibrillator in preventing non-ischaemic heart failure

NTU Singapore setting up new institute to find cures for human diseases

Researchers report first evidence of Seoul hantavirus in wild rats in the Netherlands

Researchers discover molecular 'switch' that controls replication, transcription of mitochondria DNA

Widely used clinical calculators overrate heart attack risk

New laser technology shows promise for cancer treatment

Breast density laws could pose risk of unnecessary procedures for women with breast cancer

New electronic model holds promise of revolutionizing shared decision-making in doctor's office

New study indicates that cancer patients rarely push for unnecessary tests, treatments

Increasing opioid doses to manage chronic pain may intensify depression

MJC ICM works out general guidelines for intensive care medicine

Techimmuna may help diagnose rheumatoid arthritis

Adult survivors of childhood cancer at risk for pituitary hormone deficiencies

Short-term cognitive behavioral therapy reduces suicide attempts among at-risk soldiers

R. Bryan Miller Symposium to spotlight special focus on rare disease research

Novartis receives priority review status from FDA for heart failure medicine LCZ696

Consortium formed to develop program to improve health outcomes for Ebola patients

Researchers develop novel strategy in fight against cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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