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Research pinpoints critical age for improving children's cardiovascular health

Cardiovascular disease (CVD) is a critical public health concern, with risk factors such as high blood pressure, abnormal blood sugar levels, elevated cholesterol, and obesity beginning in childhood.

18 Dec 2024

Understanding metformin's mechanism in reducing blood sugar

Millions of people take metformin, a Type 2 diabetes medication that lowers blood sugar. The "wonder drug" has also been shown to slow cancer growth, improve COVID outcomes and reduce inflammation. But until now, scientists have been unable to determine how, exactly, the drug works.

18 Dec 2024

New insights into Sjögren's disease pathogenesis and treatment

Researchers at NYU College of Dentistry and NYU Grossman School of Medicine are closer to understanding what drives the autoimmune disorder Sjögren's disease, thanks to new discoveries about the role of calcium signaling, regulatory T cells, and interferon.

18 Dec 2024

AI-based aging clocks offer insights into health and lifespan

Researchers at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London have conducted a comprehensive study to evaluate artificial intelligence based aging clocks, which predict health and lifespan using data from blood.

18 Dec 2024

Sleep disruptions may increase brain volume in the hippocampus

People with breathing problems during sleep may have a larger hippocampus, the area of the brain responsible for memory and thinking, according to a study published in the December 18, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

18 Dec 2024

New approach in fighting leukemia with double-modified natural killer cells

Various forms of blood cancer exist – all of which are grouped together under the term leukemia. One common form of leukemia is acute myeloid leukemia (AML), characterized by a degradation of early blood cell precursors, i.e. stem cells and the precursor cells that develop from them.

18 Dec 2024

Could microalgae fermentation create the superfoods of the future?

Microalgae fermentation unlocks sustainable and nutritious food production, offering bioactive peptides with antidiabetic properties but faces challenges in consumer acceptance.

18 Dec 2024

Clinical trial to evaluate minimally invasive procedure for women with pelvic venous disease

A multicenter randomized, controlled clinical trial aims to test whether a minimally invasive treatment can relieve chronic pelvic pain and improve the quality of life for women with pelvic venous disease (PeVD).

18 Dec 2024

Modified lipid nanoparticles for targeted mRNA delivery to the brain

Penn Engineers have modified lipid nanoparticles (LNPs) - the revolutionary technology behind the COVID-19 mRNA vaccines - to not only cross the blood-brain barrier (BBB) but also to target specific types of cells, including neurons.

18 Dec 2024

Nutraceuticals: exploring potential benefits and challenges of an unregulated healthcare frontier

Nutraceuticals offer potential health benefits, from migraine relief to cognitive support, but safety and regulatory issues must be addressed for effective use.

18 Dec 2024

Study reveals gaps in gestational diabetes diagnosis in pregnant women

Research investigating testing methods for gestational diabetes suggests that over half of pregnant women with the condition are not being diagnosed with the current NHS blood test process, leading to unnecessary complications for mother and baby.

17 Dec 2024

Heat waves pose unique threats to people with Parkinson's and dementia

As 2024 is set to end as Earth's hottest year on record – breaking the previous record set in 2023– a UCLA Health researcher says people living with neurodegenerative diseases will be uniquely vulnerable to worsening heat waves because of a higher risk of heat-related complications.

17 Dec 2024

Huntsman Cancer Institute joins innovative clinical trials program for blood cancers

Huntsman Cancer Institute at the University of Utah (the U) has joined other institutions in an innovative clinical trials program designed to match patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) with a clinical trial specifically designed for the genetic signature of their disease.

17 Dec 2024

Researchers receive NIH grant to study dementia caused by cerebral small vessel disease

Researchers at Washington University School of Medicine in St. Louis have been awarded $7.5 million from the National Institutes of Health (NIH) to investigate a form of dementia caused by cerebral small vessel disease, the second-leading cause of dementia after Alzheimer's disease.

17 Dec 2024

Breakthrough pig kidney transplant ends dialysis for Alabama woman

An Alabama woman is free from dialysis and in better health after surgeons at NYU Langone Health performed a gene-edited pig kidney transplant last month.

17 Dec 2024

A comprehensive review of atrial fibrillation

In the U.S., atrial fibrillation (AF), a heart condition that causes an irregular heartbeat in the upper chambers of the heart, affects up to one in three people in their lifetime.

17 Dec 2024

Knowing the risks, Americans still sip sugary beverages daily

Health knowledge about sugar-sweetened beverages (SSBs) does not significantly reduce high SSB consumption, which is driven more by taste, habits, and marketing.

17 Dec 2024

Scientists discover key protein that helps cancer cells evade CAR T cell therapy

Scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, have collared a tricky culprit that helps cancer cells evade CAR T cell therapy.

17 Dec 2024

Researchers uncover key mechanisms in blood vessel formation

The formation of blood vessels is a complex process involving the interplay of proteins and mechanic forces.

17 Dec 2024

New blood test offers non-invasive way to detect heart transplant rejection

A blood test can show whether a new heart is tolerated by the recipient and not rejected. This has been shown in a thesis from the University of Gothenburg, Sweden.

17 Dec 2024