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Researchers identify potential therapeutic target for glioblastoma

A multicenter team of researchers has identified an enzyme key to the survival and spread of glioblastoma cancer cells that is not present in healthy brain cells, making the enzyme a promising therapeutic target.

4 Nov 2014

Anesthetics can cause long-term memory loss, reveal University of Toronto researchers

Researchers at the University of Toronto's Faculty of Medicine have shown why anesthetics can cause long-term memory loss, a discovery that can have serious implications for post-operative patients.

4 Nov 2014

Scientists obtain first structure of the immature form of HIV

Scientists at the European Molecular Biology Laboratory in Heidelberg, Germany and collaborators from Heidelberg University, in the joint Molecular Medicine Partnership Unit, have obtained the first structure of the immature form of HIV at a high enough resolution to pinpoint exactly where each building block sits in the virus.

4 Nov 2014

UC Davis researchers link increased body fat and lethal drug reactions in mice

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found. The findings, published online today in The Journal of Experimental Medicine, suggest a possible link between body fat and the risk of toxicity from some types of immunotherapy.

3 Nov 2014

U-M receives $1.6 million federal grant to study potential social and environmental links to autism

University of Michigan researchers will use a new $1.6 million federal grant to probe potential social and environmental links to autism, collecting location-specific information from tens of thousands of affected individuals and their families nationwide.

3 Nov 2014

March of Dimes calls for nationwide effort to reduce U.S. preterm births to 5.5% by 2030

The March of Dimes is calling for a nationwide effort to reduce U.S. preterm births to 5.5 percent of all live births by 2030. Seven other developed countries already have preterm birth rates below 6 percent, and 15 have rates below 7 percent.

3 Nov 2014

New policy targeting hospital readmissions for COPD may hurt vulnerable patients, say experts

Last week, the federal government revealed that it will fine more than 2,600 hospitals in the coming year, because too many Medicare patients treated at these hospitals are ending up back in the hospital within 30 days of going home. Two new conditions have been added in this round of penalties: elective hip and knee replacement and chronic lung disease.

3 Nov 2014

New research sheds light on future efforts to eradicate HIV from the body in human patients

Where does HIV hide? Antiretroviral drugs can usually control the virus, but can't completely eliminate it. So any strategy to eradicate HIV from the body has to take into account not only the main group of immune cells the virus targets, called CD4 or helper T cells, but other infected cells as well.

3 Nov 2014

FDA approves Fluzone High-Dose vaccine sBLA to include efficacy data in Prescribing Information

Sanofi Pasteur, the vaccines division of Sanofi, today announced that the U.S. Food and Drug Administration has approved the supplemental biologics license application (sBLA) for Fluzone High-Dose (Influenza Vaccine) to include efficacy data in the Prescribing Information.

3 Nov 2014

Novo Nordisk introduces NovoRapid PumpCart insulin pump

Today, Novo Nordisk launches NovoRapid PumpCart, the first prefilled pump cartridge with an insulin analogue that has been specifically designed for insulin pumps. This new treatment solution, which contains NovoRapid (insulin aspart) – a rapid-acting insulin from Novo Nordisk – is expected to make insulin pump therapy more convenient for people with diabetes and their care staff.

From Novo Nordisk 3 Nov 2014

Researchers to develop new tests to evaluate cognitive growth in people with intellectual disability

Leading researchers, funded through a new, five-year, $3.2 million grant from the National Institutes of Health, are collaborating to develop and evaluate tests designed to measure and track changes in the cognitive functioning of people who typically are difficult to assess accurately: those with an intellectual disability, formerly termed mental retardation.

3 Nov 2014

Wimpy antibody prevents more serious self-inflicted forms of kidney disease, researchers say

An antibody abundant in mice and previously thought to offer poor assistance in fighting against infection may actually play a key role in keeping immune responses in check and preventing more serious self-inflicted forms of kidney disease, researchers say.

3 Nov 2014

Gates Foundation awards US$156 million to support PATH Malaria Vaccine Initiative

In support of a bold quest to rid the world entirely of malaria, the Bill & Melinda Gates Foundation today announced an award of US$156 million to PATH to support the PATH Malaria Vaccine Initiative (MVI) in building new vaccines that will interrupt the cycle of malaria parasite transmission and help realize the "accelerating to zero" agenda. Such vaccines would ensure that parasite reintroduction is prevented by providing what could be called an "immunological bed net."

3 Nov 2014

RDoC research initiative aims to help guide classification of patients in clinical studies

A new effort by the National Institutes of Health will facilitate communication among scientists, clinicians, and the public to reframe mental health research, from diagnosis to treatment. The Research Domain Criteria (RDoC) unit was recently established by the National Institute of Mental Health, part of NIH, to support the development of the institute's RDoC initiative.

31 Oct 2014

Researchers develop mouse model to improve basic research on Ebola treatments, vaccines

Researchers at the University of North Carolina at Chapel Hill and colleagues have developed the first genetic strain of mice that can be infected with Ebola and display symptoms similar to those that humans experience.

31 Oct 2014

Insomnia contributes to deaths caused by motor vehicle crashes, other fatal injuries

New research suggests that insomnia is a major contributor to deaths caused by motor vehicle crashes and other unintentional fatal injuries. The results underscore the importance of the "Sleep Well, Be Well" campaign of the National Healthy Sleep Awareness Project.

31 Oct 2014

PP&AR: 1 out of 4 older Americans experience unwanted medical treatment

Nearly one out of four older Americans say that either they or a family member have experienced excessive or unwanted medical treatment, according to the latest issue of The Gerontological Society of America's Public Policy & Aging Report, which goes on to show that Americans strongly support holding doctors accountable when they fail to honor patients' end-of-life health care wishes.

31 Oct 2014

Study compares five-year DFS and OS rates for patients with AIS and MIA

Lung cancer patients with minimally invasive adenocarcinoma (MIA) have similar, positive five-year disease-free survival (DFS) and overall survival (OS) rates as patients with adenocarcinoma in-situ (AIS), according to research presented today at the 2014 Chicago Multidisciplinary Symposium in Thoracic Oncology.

31 Oct 2014

Diabetes treatment with low-cost generic drug can have positive implications for patient's quality of life

New research from CVS Health finds starting a new diabetes patient on metformin, a generic oral diabetes medicine that helps control blood sugar levels, reduced the need to add on additional treatments to control the condition over time. Although there are many classes of oral diabetes medications, there has historically been little evidence available on the comparative effectiveness of treatments to help patients and providers select an initial diabetes therapy.

31 Oct 2014

LAMA/LABA combination better than monotherapy for severe COPD

Combination treatment with umeclidinium bromide and vilanterol offers clinically meaningful improvements over tiotropium monotherapy for patients with moderate-to-very severe chronic obstructive pulmonary disease, study data show.

31 Oct 2014

Medicine News and Research

Researchers identify potential therapeutic target for glioblastoma

Anesthetics can cause long-term memory loss, reveal University of Toronto researchers

Scientists obtain first structure of the immature form of HIV

UC Davis researchers link increased body fat and lethal drug reactions in mice

U-M receives $1.6 million federal grant to study potential social and environmental links to autism

March of Dimes calls for nationwide effort to reduce U.S. preterm births to 5.5% by 2030

New policy targeting hospital readmissions for COPD may hurt vulnerable patients, say experts

New research sheds light on future efforts to eradicate HIV from the body in human patients

FDA approves Fluzone High-Dose vaccine sBLA to include efficacy data in Prescribing Information

Novo Nordisk introduces NovoRapid PumpCart insulin pump

Researchers to develop new tests to evaluate cognitive growth in people with intellectual disability

Wimpy antibody prevents more serious self-inflicted forms of kidney disease, researchers say

Gates Foundation awards US$156 million to support PATH Malaria Vaccine Initiative

RDoC research initiative aims to help guide classification of patients in clinical studies

Researchers develop mouse model to improve basic research on Ebola treatments, vaccines

Insomnia contributes to deaths caused by motor vehicle crashes, other fatal injuries

PP&AR: 1 out of 4 older Americans experience unwanted medical treatment

Study compares five-year DFS and OS rates for patients with AIS and MIA

Diabetes treatment with low-cost generic drug can have positive implications for patient's quality of life

LAMA/LABA combination better than monotherapy for severe COPD

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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