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New molecular sensor could identify zinc-related diseases

Scientists have developed a new molecular sensor that can reveal the amount of zinc in cells, which could tell us more about a number of diseases, including type 2 diabetes. The research, published today in Nature Methods, opens the door to the hidden world of zinc biology by giving scientists an accurate way of measuring the concentration of zinc and its location in cells for the first time.

30 Aug 2009

Research journal to host a webinar on apoptotic signalling in normal and cancer cell biology

The business office of Science, the world's leading peer-reviewed research journal, is producing a webinar on "Apoptotic Signaling in Normal and Cancer Cell Biology" to be broadcast live online at 12 noon ET (4:00 GMT) September 22, 2009, sponsored by Promega.

29 Aug 2009

Astrocytes play a key role in the generation of fMRI signals

Functional magnetic resonance imaging (fMRI) is a technique widely used in studying the human brain. However, it has long been unclear exactly how fMRI signals are generated at brain cell level. This information is crucially important to interpreting these imaging signals. Scientists from the Academy of Finland's Neuroscience Research Programme (NEURO) have discovered that astrocytes, support cells in brain tissue, play a key role in the generation of fMRI signals.

29 Aug 2009

Two human biomarker assays that play a key role in the early detection of kidney damage provide assistance in drug development

Geneuity Clinical Research Services announces the recent validation and use in clinical trials of two human biomarker assays that play a key role in the early detection of kidney damage.

29 Aug 2009

Antibiotic functioning as an off switch being developed for gene therapy of Parkinson's disease

A common antibiotic can function as an "off switch" for a gene therapy being developed for Parkinson's disease, according to University of Florida researchers writing online in advance of September's Molecular Therapy.

29 Aug 2009

Scientists study the impact of nerve growth factors for treating Parkinson's disease

Scientists in the Academy of Finland's Neuroscience Research Programme have reported promising new results with potential implications for the treatment of Parkinson's disease. They have been studying the impacts of nerve growth factors in the treatment of PD, and their latest results show that a certain growth factor can be used to halt the progress of damage brought on by a nerve poison and possibly even restore the function of damaged cells.

28 Aug 2009

Facet Biotech And Trubion to jointly develop and commercialize the TRU-016 SMIP protein therapeutic

Facet Biotech Corporation (Nasdaq: FACT) and Trubion Pharmaceuticals, Inc. (Nasdaq: TRBN) today announced an agreement for the joint worldwide development and commercialization of TRU-016, a product candidate in phase 1 clinical development for chronic lymphocytic leukemia (CLL).

28 Aug 2009

Researches report new results that may help in better treament for patients with Parkinson's disease

28 Aug 2009

ASHG 2009 Annual Meeting to discuss the cutting-edge developments in human genetics and genomics research

The world's top scientists and clinicians in the human genetics field will gather in Honolulu, Hawaii to present their latest research findings at the 59th Annual Meeting of the American Society of Human Genetics, from Tuesday, October 20, through Saturday, October 24, 2009, at the Hawaii Convention Center.

28 Aug 2009

Study on basic mechanisms that control fertility in worms may help to know how some woman regain their fertility after cancer treatment

Scientific dogma has long asserted that females are born with their entire lifetime's supply of eggs, and once they're gone, they're gone. New findings by researchers at Fred Hutchinson Cancer Research Center, published online Aug. 27 in Science, suggest that in nematode worms, at least, this does not hold true.

28 Aug 2009

Albert Einstein College of Medicine receives $11.2 million NIH grant to study genes associated with longevity

The National Institutes of Health (NIH) has awarded Albert Einstein College of Medicine of Yeshiva University a five-year, $11.2 million grant to study the impact of damage to DNA on aging and disease. Research funded by this grant, and conducted by a consortium of scientists, could reveal the role of genome maintenance systems in delaying aging and will begin to explore novel interventions to maintain health in old age.

28 Aug 2009

Urine LAM-ELISA's sensitivity of 50.7% in identifying TB disappoints

Urine LAM-ELISA does not appear to be useful as an independent diagnostic test for pulmonary tuberculosis (TB). A trial of the new diagnostic, described in the open access journal BMC Infectious Diseases found that it was only capable of identifying 50.7% of TB cases.

28 Aug 2009

Study reveals the mechanisms of sodium tungstate in treating diabetes

The molecular mechanisms of tungstate activity in diabetes have been uncovered. Researchers writing in the open access journal BMC Genomics have identified the pathways through which sodium tungstate improves pancreatic function and beta cell proliferation.

28 Aug 2009

Enzymes could be targeted to kill dangerous pathogens

Researchers at Burnham Institute for Medical Research (Burnham), University of Texas Southwestern Medical Center and University of Maryland have demonstrated that an enzyme that is essential to many bacteria can be targeted to kill dangerous pathogens.

28 Aug 2009

Iowa researchers modify siRNA for impacting targeted cells in cancer treatment

Small interfering RNA (siRNA), a type of genetic material, can block potentially harmful activity in cells, such as tumor cell growth. But delivering siRNA successfully to specific cells without adversely affecting other cells has been challenging.

28 Aug 2009

TRAF6 protein can activate a cell signalling molecule associated with cancer

The mainstay immune system protein TRAF6 plays an unexpected, key role activating a cell signaling molecule that in mutant form is associated with cancer growth, researchers at The University of Texas M. D. Anderson Cancer Center report in the Aug. 28 edition of Science.

28 Aug 2009

Comprehensive review on the pharmacology of sigma receptors published in Journal of Pharmacology Therapeutics

Anavex Life Sciences Corp. ("ANAVEX" or the "Company") reports the publication of a comprehensive review of the pharmacology of sigma receptors and their possible clinical application in the peer-reviewed Journal of Pharmacology Therapeutics.

28 Aug 2009

Abbott to partner with Pfizer to develop a companion diagnostic test for non-small cell lung cancer

Abbott announced today that it has entered into an agreement with Pfizer Inc to develop a molecular diagnostic test intended to screen non-small cell lung cancer (NSCLC) tumors for the presence of gene rearrangements.

28 Aug 2009

AVI BioPharma's peptide-conjugated PMO chemistry to be discussed at two upcoming scientific meetings

AVI BioPharma, Inc., a developer of RNA-based drugs, today announced that Hong Moulton, Ph.D., Director of Discovery Research, will give oral presentations highlighting improved analogues of AVI's phosphorodiamidate morpholino oligomer (PMO) chemistry at two upcoming scientific meetings.

28 Aug 2009

Medical journal article highlights the challenges faced by healthcare providers for treating patients with non-healing wounds

Cardium Therapeutics today reported that a recent medical journal article highlights the challenges facing healthcare providers with respect to finding optimal treatments for patients with non-healing wounds.

28 Aug 2009

Cell News and Research

New molecular sensor could identify zinc-related diseases

Research journal to host a webinar on apoptotic signalling in normal and cancer cell biology

Astrocytes play a key role in the generation of fMRI signals

Two human biomarker assays that play a key role in the early detection of kidney damage provide assistance in drug development

Antibiotic functioning as an off switch being developed for gene therapy of Parkinson's disease

Scientists study the impact of nerve growth factors for treating Parkinson's disease

Facet Biotech And Trubion to jointly develop and commercialize the TRU-016 SMIP protein therapeutic

Researches report new results that may help in better treament for patients with Parkinson's disease

ASHG 2009 Annual Meeting to discuss the cutting-edge developments in human genetics and genomics research

Study on basic mechanisms that control fertility in worms may help to know how some woman regain their fertility after cancer treatment

Albert Einstein College of Medicine receives $11.2 million NIH grant to study genes associated with longevity

Urine LAM-ELISA's sensitivity of 50.7% in identifying TB disappoints

Study reveals the mechanisms of sodium tungstate in treating diabetes

Enzymes could be targeted to kill dangerous pathogens

Iowa researchers modify siRNA for impacting targeted cells in cancer treatment

TRAF6 protein can activate a cell signalling molecule associated with cancer

Comprehensive review on the pharmacology of sigma receptors published in Journal of Pharmacology Therapeutics

Abbott to partner with Pfizer to develop a companion diagnostic test for non-small cell lung cancer

AVI BioPharma's peptide-conjugated PMO chemistry to be discussed at two upcoming scientific meetings

Medical journal article highlights the challenges faced by healthcare providers for treating patients with non-healing wounds

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