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Unveiling INST10's role in neural development and cell identity

The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular "bridge" complex demonstrate a new level of detail in the understanding of early neural development - which is fundamental for the further understanding of neurodevelopmental syndromes.

27 Nov 2024

Epigenetic profiles of blood cancer cells could aid in diagnosis and treatment

Research in biomedical laboratories has been changing significantly in recent years, to the point that test tubes have given way to computers on many occasions.

27 Nov 2024

McMaster University develops fast and easy test for bacteria detection in fluids

A novel new test for bacteria in fluids makes it as easy as observing a color change to confirm the presence of disease-causing pathogens, promising much easier diagnostic tests and greater food safety.

26 Nov 2024

Routine health checks for heart disease risk did not recover fully after the pandemic

Routine screening to detect risk factors for heart disease dropped sharply during the COVID-19 pandemic in England, and some key measurements, such as blood pressure readings, may still lag behind pre-pandemic levels.

26 Nov 2024

Late-liver-stage malaria vaccine delivers 89% protection and boosts cellular immunity

Genetically attenuated malaria parasites with extended liver-stage arrest (GA2) showed 89% protection in a clinical trial, surpassing earlier vaccine candidates and highlighting the potential of cellular immunity.

26 Nov 2024

Scientists develop method to study malaria's sticky proteins

Scientists have unveiled a new tool for studying the highly variable traits that allow malaria parasites to stick to red blood cells and evade the immune system.

26 Nov 2024

Cardiovascular disease risk linked to early brain decline in men

Men with cardiovascular disease risk factors, including obesity, face brain health decline a decade earlier - from their mid 50s to mid 70s - than similarly affected women who are most susceptible from their mid 60s to mid 70s, suggest the findings of a long term study, published online in the Journal of Neurology Neurosurgery & Psychiatry.

26 Nov 2024

Emory University Hospital performs first U.S. implant of novel ventricular assist device

On Nov. 18, the heart failure and transplantation team at Emory University Hospital (EUH) made history, performing the first-ever surgical implantation in the United States of a brand-new type of ventricular assist device (VAD), which provides crucial care to patients with failing hearts.

26 Nov 2024

Research highlights key health benefits of drinking more water

Public health recommendations generally suggest drinking eight cups of water a day. And many people just assume it's healthy to drink plenty of water.

26 Nov 2024

Placental defects linked to congenital heart defects

Congenital heart defects are the most common form of human birth defect, but we still don't fully understand what causes them.

26 Nov 2024

Innovative tool enhances the accuracy of predicting survival outcomes for liver failure patients

Researchers have unveiled a groundbreaking advancement in liver failure care: the CATCH-LIFE-MELD score (Chinese Acute-on-Chronic Liver Failure Consortium (CATCH-LIFE)-MELD score).

26 Nov 2024

First U.S. trial uses non-viral CRISPR to correct sickle cell mutation

UCSF Benioff Children's Hospital Oakland is enrolling patients in an innovative clinical trial that seeks to cure sickle cell disease.

26 Nov 2024

Machine learning tool detects early signs of Alzheimer's in mice

Subtle signs of Alzheimer's disease can emerge decades before a diagnosis - often in the form of irregular behaviors that reflect very early stages of brain dysfunction.

26 Nov 2024

Tirzepatide cuts diabetes risk by 90% in obese patients, study shows

Tirzepatide, a new injectable weight-loss drug with the trade name Zepbound, reduced the risk of diabetes in patients with obesity and prediabetes by more than 90% over a three-year period, compared with placebo, according to the results of a new study led by investigators at Weill Cornell Medicine, NewYork-Presbyterian, Yale School of Medicine and other institutions.

26 Nov 2024